Yazar "Cüre, Erkan" için listeleme
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Prognostic value of mean platelet volume and neutrophil to lymphocyte ratio in patients with Crimean-Congo Hemorrhagic Fever
Amaç: Kırım-Kongo Kanamalı Ateşi (KKHA) virüsü, Bunyaviridae ailesine üye Nairovirus olup insanlarda ciddi hastalığa neden olur. KKKA enfeksiyonunda pansitopeni, organ yetersizliği ve yaygın damar-içi pıhtılaşma ortaya ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Tümkaya, Levent; Aydın, İbrahim; Kırbaş, Aynur; Efe, Hasan; Kurt, Aysel; Yüce, Süleyman (Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
Kurt, Aysel; Tümkaya, Levent; Yüce, Süleyman; Türüt, Hasan; Cüre, Medine Cumhur; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Pusuroğlu, Gökhan; Cüre, Erkan (Mashhad Univ Med Sciences, 2016)Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ... -
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Özer, Ender; Cüre, Medine Cumhur; Yüce, Süleyman; Kalkan, Yıldıray; Cüre, Erkan (Begell House Inc, 2015)Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ... -
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
Aydın, İbrahim; Kalkan, Yıldıray; Özer, Ezgi Demir; Yücel, Ahmet Fikret; Pergel, Ahmet; Cüre, Erkan; Cüre, Medine Cumhur; Şahin, Dursun Ali (Verduci Publisher, 2014)OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Kalkan, Yıldıray; Yılmaz, Arif; Yüce, Süleyman (Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
Protective effects of infliximab on lung injury induced by methotrexate
Kurt, Aysel; Tümkaya, Levent; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Şehitoğlu, İbrahim; Acıpayam, Ahmet (Elsevier Espana Slu, 2015)Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ... -
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
Erkut, Adem; Cüre, Medine Cumhur; Kalkan, Yıldıray; Balık, Mehmet Sabri; Güvercin, Yılmaz; Yaprak, Esra; Yüce, Süleyman; Şehitoğlu, İbrahim; Cüre, Erkan (Verduci Publisher, 2016)OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ... -
The relationship between atherogenic index and carotid artery atherosclerosis in familial mediterranean fever: A pilot study
İçli, Abdullah; Cüre, Erkan; Uslu, Ali Uğur; Sakız, Davut; Cüre, Medine Cumhur; Özuçan, Miyase; Baykara, Rabia Aydoğan; Karakoyun, Ahmet; Balta, Şevket; Öztürk, Cengiz; Arslan, Şevket; Küçük, Adem (Sage Publications Inc, 2017)Familial Mediterranean fever (FMF) is a disease characterized by chronic inflammation. Atherogenic index of plasma (AIP) is a logarithmic value of the triglyceride to high-density lipoprotein cholesterol ratio and it is a ... -
Relationships between C-kit expression and mean platelet volume in benign, preneoplastic and neoplastic endometrium
Şehitoğlu, İbrahim; Bedir, Recep; Ural, Ülkü Mete; Güçer, Hasan; Yurdakul, Cüneyt; Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Şahin, Figen Kır (Asian Pacific Organization for Cancer Prevention, 2015)Background: c-Kit is a proto-oncogene that encodes a tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker for demonstrating thrombocyte function. We aimed to investigate whether c-kit is expressed ... -
Requests for tumor marker tests in Turkey without indications and frequency of elevation in benign conditions
Cüre, Medine Cumhur; Cüre, Erkan; Kırbaş, Aynur; Yazıcı, Tarkan; Yüce, Süleyman (Asian Pacific Organization Cancer Prevention, 2012)Aims: To investigate the incidence of ordering tests for tumor markers which are used in cancer diagnosis, follow-up treatment and detection of recurrence, the rate of elevation in benign diseases and which clinics order ... -
Rize ilinde erişkin yaş gruplarında Hepatit A seroprevalansı
Amaç: Bu çalışmada Rize ilinde yaş grupları için Hepatit A (HAV) seroprevalansını araştırmayı amaçladık. Bunun yanısıra, “Genişletilmiş Ulusal Bağışıklama Programı’nın” hepatit A aşısı eklenerek başlatıldığı sürecin öncesinde ... -
Serum fibronectin levels in acute and chronic viral hepatitis patients
Ertürk, Ayşe; Cüre, Erkan; Özkurt, Zülal; Parlak, Emine; Cüre, Medine Cumhur (Malaysian Journal of Medical Sciences, 2014)Background: The aim of this study was to investigate the serum fibronectin (FN) levels and liver enzyme activities in patients with acute hepatitis (A, B, C) and chronic viral hepatitis (B, C); determine whether the virus ... -
Serum levels of homocysteine, asymmetric dimethylarginine and nitric oxide in patients with Parkinson's disease
Kırbaş, Serkan; Kırbaş, Aynur; Tufekçi, Ahmet; Cüre, Medine Cumhur; Çakmak, Sevim; Yazıcı, Tarkan; Cüre, Erkan (Taylor & Francis Ltd, 2016)Objectives: Endothelial dysfunction has been implicated as a crucial event in the development of several neurodegenerative diseases. the aim of this study was to investigate the serum homocysteine, asymmetric dimethylarginine ... -
Serum resistin levels may be new prognostic factor of crimean-congo hemorrhagic fever
Ertürk, Ayşe; Cüre, Erkan; Parlak, Emine; Cüre, Medine Cumhur; Yüce, Süleyman; Kızılkaya, Bayram (E-Century Publishing Corp, 2014)Crimean-Congo hemorrhagic fever (CCHF) virus can cause potentially fatal infections in humans. During this disease, cytokines are intensive released. Resistin which is a good marker of inflammation is an adipocytokine ... -
Somatostatin receptor 2 and 5 expressions in gastroenteropancreatic neuroendocrine tumors in Turkey
Yerci, Ömer; Şehitoğlu, İbrahim; Uğraş, Nesrin; Çubukcu, Erdem; Yüce, Süleyman; Bedir, Recep; Cüre, Erkan (Asian Pacific Organization for Cancer Prevention, 2015)Background: Gastroenteropancreatic neuroendocrine tumors (GNs) are slow growing and although their incidence has increased in recent years, they are relatively rarely seen. Somatostatin analogues are used in the treatment ... -
Steatozlu Hastalarda Blink Refleksin Değerlendirilmesi
Cüre, Erkan; Kırbaş, Serkan; Cüre, Medine Cumhur; Tüfekci, Ahmet; Kırbaş, Aynur; Yüce, Süleyman; Oğullar, Sabri (2015)Blink refleks (BR) nöropatileri değerlendirmek için kullanılan yararlı bir elektrodiagnostik yöntemdir. Biz bu çalışmada basit steatozda nöropatinin erken tanısında BR'in rolünü incelemeyi amaçladık. Materyal ve Metod: ... -
Syncope in a patient with spontaneous hemorrhage into a thyroid nodule
Şahin, Serap Baydur; Belice, Tahir; Oğullar, Sabri; Ayaz, Teslime; Cüre, Erkan (Lithographia, 2014)Background: Spontaneous hemorrhage into a thyroid nodule occurs exceedingly rare and rarely a neck hematoma can develop. We report a case of syncope due to spontaneous hemorrhage into a thyroid nodule during anticoagulant ... -
Tear film osmolarity in patients with graves ophthalmopathy
Türkyılmaz, Kemal; Öner, Veysi; Şahin, Serap Baydur; Cüre, Erkan; Cüre, Cumhur; Kola, Mehmet; Durmuş, Mustafa (Tıp Araştırmaları Derneği, 2014)To investigate changes of tear osmolarity in patients with Graves ophthalmopathy (GO). Twenty-three patients with GO (GO group) and 25 healthy controls (control group) were enrolled in the study. GO patients were divided ...