Yazar "Mercantepe, Tolga" için listeleme
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Manyetik Rezonans Kontrast Ajanların Sıçan Beyni Üzerine Etkilerinin Histopatolojik Değerlendirilmesi
Çeliker, Fatma Beyazal; Tümkaya, Levent; Mercantepe, Tolga; Beyazal, Mehmet; Turan, Arzu; Burakgazi, Gülen; Hürsoy, Nur (2023)Amaç: Gadolinyum tabanlı kontrast ajanlar (GBCA), manyetik rezonans görüntülemelerde (MRG) kontrast sağlamak amaçlı kullanılmaktadır. GBKA yapısına bağlı olarak beyin dokusu ve diğer dokularda birikim olduğu ile ... -
Melatonin ameliorates periodontitis related inflammatory stress at cardiac left ventricular tissues in rats
Köse, Oğuz; Bayraktar, Sevda Kurt; Akyıldız, Kerimali; Altın, Ahmet; Arabacı, Taner; Yemenoğlu, Hatice; Korkmaz, Mehmet Zihni; Köse, Taha Emre; Şener, Leyla Türker; Mercantepe, Tolga; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2020)BackgroundThe aim of this experimental rat study was to investigate the potential inflammatory effects of periodontitis on cardiac left ventricular tissue and the therapeutic activity of melatonin on these effects. ... -
Melatonin improves periodontitis-induced kidney damages by decreasing inflammatory stress and apoptosis in rats
Köse, Oğuz; Bayrakdar, Sevda Kurt; Ünver, Büşra; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Arabacı, Taner; Türker Şener, Leyla; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan; Kuluşlu, Göker (Wiley-Blackwell, 2020)Background: Two main aims of this animal study were to inspect the possible effects of periodontitis on the structure and functions of the kidneys and the therapeutic effectiveness of melatonin. Methods: Twenty-four male ... -
Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900 MHz electromagnetic field during early and mid-adolescence
Ikinci, Ayse; Mercantepe, Tolga; Unal, Deniz; Erol, Huseyin Serkan; Sahin, Arzu; Aslan, Ali; Odaci, Ersan (Elsevier, 2016)The effects of devices emitting electromagnetic field (EMF) on human health have become the subject of intense research among scientists due to the rapid increase in their use. Children and adolescents are particularly ... -
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
Batçık, Şule; Tümkaya, Levent; Mercantepe, Tolga; Atak, Mehtap; Topçu, Atilla; Uydu, Hüseyin Avni; Mercantepe, F. (Verduci Editore, 2022)OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ... -
Neuroprotective effects of Vaccinium myrtillus on damage-related brain injury
Özdemir, Abdullah; Mercantepe, Tolga; Erdivanlı, Başar; Şen, Ahmet; Mercantepe, Filiz; Tümkaya, Levent; Uydu, Hüseyin Avni (2023)Traumatic brain injury may trigger the secondary brain injury, which has the potential to be reversible and thus preventable. Anthocyanins are phylotherapeutic plants, which are reported to exhibit anti-inflammatory ... -
A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results
Bozkurt, Aliseydi; Budak, Harun; Erol, Hüseyin Serkan; Can, Serpil; Mercantepe, Tolga; Akın, Yiğit; Özbey, İsa; Çankaya, Murat; Halıcı, Mesut Bünyamin; Çoban, T. Abdülkadir (Taylor & Francis Ltd, 2018)Cystitis is defined as an inflammation of the bladder caused by a bacterial infection, and it can be dangerous and painful when it spreads through the internal organs. in this study, antioxidant effects of hydroxylfasudil ... -
Pathological effects of prenatal exposure to a 900 MHz electromagnetic field on the 21-day-old male rat kidney
Odacı, Ersan; Ünal, Deniz Sönmez; Mercantepe, Tolga; Topal, Zehra Suzan; Hancı, Hatice; Türedi, Sibel; Erol, Hüseyin Serkan; Mungan, Sevdegül; Kaya, Haydar; Çolakoğlu, Serdar (Taylor & Francis Ltd, 2015)We investigated the effects on kidney tissue of 900 megahertz (MHz) EMF applied during the prenatal period. Pregnant rats were exposed to 900 MHz EMF, 1 h/day, on days 13-21 of pregnancy; no procedure was performed on ... -
Pathological findings observed in the kidneys of postnatal male rats exposed to the 2100 MHz electromagnetic field
Bedir, Recep; Tümkaya, Levent; Mercantepe, Tolga; Yılmaz, Adnan (Elsevier Science Inc, 2018)Background. the widespread use by young people of modern communication devices such as mobile phones means that they are particularly exposed to electromagnetic fields (EMF) and other problems. However, few studies have ... -
Pelvic radiation-induced testicular damage: an experimental study at 1 gray
Rakıcı, Sema Yılmaz; Güzel, Ali İrfan; Tümkaya, Levent; Nalkıran, Hatice Sevim; Mercantepe, Tolga (Taylor & Francis Inc, 2020)Therapeutic radiation of the pelvic region has been shown to cause damage to testicular germ cells. in this study we aimed to evaluate the effects of a low therapeutic dose of 1 Gy on the induction of cellular and histological ... -
Periodontitis exacerbates the renal degenerative effects of obesity in rats
Kurt-Bayrakdar, Sevda; Köse, Oğuz; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2021)Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ... -
The potential antioxidant effect of N-acetylcysteine on X-ray ionizing radiation-induced pancreas islet cell toxicity
Yılmaz, Hamit; Mercantepe, Tolga; Tümkaya, Levent; Merca; Yılmaz, Adnan; Rakıcı, Sema Yılmaz (Elsevier, 2023)Purpose Previous research has highlighted the impact of X-ray irradiation-induced organ damage, on cancer patients after radiation therapy. The ionizing radiation-induced oxidative stress causes injury to the pancreatic ... -
Prenatal Dönemde 900Mhz Elektromanyetik Alanın Sıçan Omurilik Dokusu Üzerine Etkilerinin Histopatolojik Olarak İncelenmesi
Mercantepe, Tolga; Tümkaya, Levent; Gökçe, Fatih Mehmet; Uzunok, Barış; Suzan, Zehra Topal; Çınar, Seda; Esmer, Erva (2018)Amaç: Günümüzde yaşantımıza giren ve giderek artan belli bir frekansta elektromanyetik dalga yayılımına neden olan teknolojik cihazlar insanları elektromanyetik alana maruz bırakmaktadır. Bu cihazlar tarafından yayılan ... -
Prenatal effects of a 1,800-MHz electromagnetic field on rat livers
Tümkaya, Levent; Yılmaz, Adnan; Akyıldız, Kerimali; Mercantepe, Tolga; Yazıcı, Zihni Acar; Yılmaz, Hamit (Karger, 2019)The use of devices, including mobile phones, generating electromagnetic fields (EMF) is widespread and is progressively increasing. It has also been shown that EMF may have detrimental effects. This is the first study to ... -
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
Bostan, Semih Alperen; Yemenoğlu, Hatice; Köse, Oğuz; Akyıldız, Kerimali; Mercantepe, Tolga; Saral, Sinan; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2024)Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ... -
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats
Kaya, Habibe Budak; Polat, Beyzagül; Albayrak, Aabdulmecit; Mercantepe, Tolga; Büyük, Başak (Sage Publications Ltd, 2018)Paracetamol (P), one of the most popular and commonly used analgesic and antipyretic agents, causes hepatotoxicity in overdoses. Amlodipine (AML), an L-type calcium channel blocker, has been shown to have anti-inflammatory ... -
Protective effect of astaxanthin against cisplatin-induced gastrointestinal toxicity in rats
Yılmaz, Yeliz; Tümkaya, Levent; Mercantepe, Tolga; Akyıldız, Kerimali (Springer Wien, 2022)Background the aim of the present study was to demonstrate astaxanthin's attenuating effects against cisplatin (CIS)-induced gastrointestinal toxicity in a rat model. Methods Thirty-two Wistar rats (weight 200-250 g) were ... -
The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats
Akça, Görkem; Eren, Hüseyin; Tümkaya, Levent; Mercantepe, Tolga; Horsanali, Mustafa Ozan; Deveci, Ezgi; Yılmaz, Adnan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)Purpose: the aim of this experimental study was to investigate the antioxidant effects of astaxanthin against cisplatin-induced nephrotoxicity in rats. Methods: Forty-eight male Sprague-Dawley rats weighing 264.83 +/- 7.39 ... -
The protective effect of astaxanthin on cisplatin-induced ototoxicity
Terzi, Suat; Özgür, Abdulkadir; Çeliker, Metin; Mercantepe, Tolga; Yılmaz, Adnan; Tümkaya, Levent; Kaya, Şeyma; Demir, Emine; Dursun, Engin (Wroclaw Medical Univercity, 2021)Background. Promising studies have been conducted with many substances to reduce the ototoxic effects of cisplatin, but there is no treatment that completely eliminates the ototoxic effect. Objectives. To determine the ... -
Protective effect of tea grape extract on cisplatin-induced muscle atrophy: A morphological study
Balık, Mehmet Sabri; Tümkaya, Levent; Mercantepe, Tolga; Yılmaz, Adnan; Balık, Gülşah; Topçu, Atilla; Yazıcı, Zihni Açar (Kowsar Publ, 2018)Background: Even though Cisplatin (Cis) is known to be organotoxic, it is used in neoplastic chemotherapy. in skeletal muscles, the toxic effect manifests as atrophy. Objectives: the tea grape extract (TGE) is a sort of ...