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Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
Ceylan, Şule; Bayrak, Hacer; ÖZdemir, Serap Başoğlu; Uygun, Yıldız; Mermer, Arif; Demirbaş, Neslihan; Ülker, Serdar (Walter de Gruyter Gmbh, 2016)Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl) ethanone. Treatment of 4a,b with base afforded ...
