Yazar "Özbayer, Cansu" için listeleme
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Akciğer kanserli hastalarda plazma dna metiltransferaz ve metil- CpG'ye bağlanan protein seviyelerinin değerlendirilmesi
Özbayer, Cansu; Üstüner, Derya Akyıldız; Ak, Güntülü Akdoğan; Saydam, Faruk; Metintaş, Muzaffer; Değirmenci, İrfan (2017)Amaç: Akciğer kanseri, akciğer doku hücrelerinin kontrolsüz çoğalmasıyla oluşan ölümcül bir hastalıktır. Çevresel faktörlerle birlikte genetik ve epigenetik değişikliklerin kanser gelişimine neden olduğu bilinmektedir. DNA ... -
Association and haplotype analysis of the PON1, ITGB3 and CYP3A4 genes, strong candidates for familial coronary artery disease susceptibility
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özbayer, Cansu; Ulus, Taner; Özdemir, Mahmut; Ata, Necmi; Güneş, Hasan Veysi (2023)Objective: Genetic predisposition is very common among the patients with coronary artery disease (CAD), a complex and multifactorial disease. Our objective was to determine the possible association between the most ... -
Common variants rs3815188 and rs1043994 on notch3 gene confer susceptibility to lung cancer: A hospital-based case-control study
Yağcı, Emine; Değirmenci, İrfan; Özbayer, Cansu; Ak, Güntulu; Saydam, Faruk; Metintaş, Muzaffer (Begell House Inc, 2019)The Notch signaling pathway is a mechanism that plays a role in the determination of cell fate during cell development. Signals between neighbor cells are amplified through the Notch receptors. Notch activity is related ... -
The CYP 2C19*2 and CYP2C19*17 polymorphisms play a vital role in platelet responsiveness to clopidogrel after percutaneous coronary intervention: a pharmacogenomic study
Saydam, Faruk; Değirmenci, İrfan; Birdane, A.; Ozdemir, M.; Ulus, T.; Özbayer, Cansu; Çolak, E.; Ata, N.; Güneş, H.V. (Elsevier, 2015)Background: Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current guidelines for patients ... -
The CYP2C19*2 and CYP2C19*17 polymorphisms play a vital role in clopidogrel responsiveness after percutaneous coronary intervention: A pharmacogenomics study
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Ulus, Taner; Özbayer, Cansu; Çolak, Ertuğrul; Ata, Necmi; Güneş, Hasan Veysi (Wiley, 2017)Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor. Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current guidelines for patients undergoing ... -
Expression and potential role of miR200b and miR1274a in lung cancer patients
Özbayer, Cansu; Ak, Güntulu Akdoğan; Üstüner, Derya; Saydam, Faruk; Güneş, Hasan Veysi; Metintaş, Muzaffer (Derman Medical Publ, 2017)Aim: Lung cancer (LC) is a fatal disease characterized by uncontrolled proliferation of airway epithelial cells and caused by genetic or environmental factors. LC is one of the most common types of cancer and the leading ... -
Haplotype analyses of CYP2C19*2 and CYP2C19*17 genetic polymorphisms in clopidogrel non-responsiveness after percutaneous coronary intervention with stent implantation
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Özbayer, Cansu; Ata, Necmi; Güneş, Hasan Veysi (Nature Publishing Group, 2018).... -
Investigation of the cyp3a4 and pon1 gene variants in turkish patients with familial coronary artery disease
Saydam, Faruk; Değirmenci, İrfan; Birdane, Alparslan; Özdemir, Mahmut; Özbayer, Cansu; Ata, Necmi; Güneş, Hasan Veysi (Lippincott Williams & Wilkins, 2015)Objective: Coronary artery disease (CAD), a complex multifactorial disorder, has been suggested to be associated by the interaction of both environmental and genetic risk factors. -
miRSNPs of miR1274 and miR3202 genes that target MeCP2 and DNMT3b are associated with lung cancer risk: A study conducted on MassARRAY genotyping
Özbayer, Cansu; Değirmenci, İrfan; Üstüner, Derya; Ak, Güntulu; Saydam, Faruk; Çolak, Ertuğrul; Güneş, Hasan Veysi; Metintaş, Muzaffer (Begell House Inc, 2016)Genetic variants of miRNAs that target DNMTs and MBDs involved in DNA methylation were scanned with current databases, and 35 miRSNPs in 22 miRNA genes were identified. the aim of the study was to determine the association ...
