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Biochemical and histopathologic analysis of the effects of periodontitis on left ventricular heart tissues of rats
Köse, Oğuz; Arabacı, Taner; Gedikli, Semin; Eminoğlu, Didem Özkal; Kermen, Eda; Kızıldağ, Alper; Kara, Hülya; Özkanlar, Seçkin; Yemenoğlu, Hatice (Wiley, 2017)Background and ObjectiveCurrent epidemiological works have suggested that chronic infections, such as periodontitis, are associated with an increased risk of cardiovascular diseases, including hypertrophy and heart failure. ... -
Effects of melatonin on oxidative stress index and alveolar bone loss in diabetic rats with periodontitis
Köse, Oğuz; Arabacı, Taner; Kara, Adem; Yemenoğlu, Hatice; Kermen, Eda; Kızılldağ, Alper; Gedikli, Semin; Özkanlar, Seçkin (Wiley, 2016)Background: the aim of this study is to evaluate the effects of systemic melatonin treatment on serum oxidative stress index (OSI) and alveolar bone loss (ABL) in rats with diabetes mellitus (DM) and periodontitis. Methods: ... -
Immune modulatory and antioxidant effects of melatonin in experimental periodontitis in rats
Kara, Adem; Akman, Sümeyra; Özkanlar, Seçkin; Tozoğlu, Ümmühan; Kalkan, Yıldıray; Çanakcı, Cenk Fatih; Tozoğlu, Sinan (Elsevier, 2013)Melatonin is an important antioxidant, and through its anti-inflammatory effects it can control immune responses, oxidative stress, and defense cell infiltration. Periodontitis is a disease of the oral cavity and the ... -
Influence of experimental periodontitis on cardiac oxidative stress in rats: a biochemical and histomorphometric study
Köse, Oğuz; Arabacı, Taner; Yemenoğlu, Hatice; Özkanlar, Seçkin; Kurt, Nezahat; Gümüşsoy, İsmail; Kara, Adem (Wiley, 2017)Background and ObjectiveThe role of oxidative stress in the process of cardiac remodeling, hypertrophy and heart failure is a current topic. the purpose of this experimental study was to investigate the influences of ... -
Influences of fucoxanthin on alveolar bone resorption in induced periodontitis in rat molars
Köse, Oğuz; Arabacı, Taner; Yemenoğlu, Hatice; Kara, Adem; Özkanlar, Seçkin; Kayış, Şevki; Duymuş, Zeynep Yeşil (Mdpi, 2016)The aim of this study was to evaluate the effects of systemic fucoxanthin treatment on alveolar bone resorption in rats with periodontitis. Thirty rats were divided into control, experimental periodontitis (EP), and ... -
Melatonin prevents radiation-induced oxidative stress and periodontal tissue breakdown in irradiated rats with experimental periodontitis
Köse, Oğuz; Arabacı, Taner; Kızılldağ, Alper; Erdemci, Burak; Eminoğlu, Didem Özkal; Gedikli, Semin; Özkanlar, Seçkin; Zihni Kormaz, Meltem; Albayrak, Mevlüt; Kara, Adem; Kermen, Eda (Wiley, 2017)Background and ObjectiveThe aim of this study was to analyze the biochemical and histochemical effects of radiation therapy and protective melatonin administration on periodontal tissues in rats with experimental periodontitis. ... -
Protective effect of Panax ginseng against serum biochemical changes and apoptosis in kidney of rats treated with gentamicin sulphate
Kalkan, Yıldıray; Kapakin, Kübra Asena Terim; Kara, Adem; Atabay, Tennur; Karadeniz, Ali; Şimşek, Nejdet; Karakuş, Emre; Can, İsmail; Yıldırım, Serap; Özkanlar, Seçkin; Şengül, Emin (Springer Link, 2012)The protective effects of Panax ginseng (PG) on gentamicin sulphate (GS) induced acute nephrotoxicity were investigated in rats. A total of 32 adult Sprague- Dawley rats were randomly divided into 4 equal groups and treated ... -
Therapeutic effects of melatonin on alveolar bone resorption after experimental periodontitis in rats: a biochemical and immunohistochemical study
Arabacı, Taner; Kermen, Eda; Özkanlar, Seçkin; Köse, Oğuz; Kara, Adem; Kızıldağ, Alper; Duman, Şuayip Burak; İbişoğlu, Ebru (Amer Acad Periodontology, 2015)Background: the present study aims to investigate the effects of systemic melatonin administration on alveolar bone resorption in experimental periodontitis in rats. Methods: Twenty-four male Sprague-Dawley rats were divided ...