Yazar "Akçay, Fatih" için listeleme
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Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes
Yapca, Ömer Erkan; Turan, Mehmet İbrahim; Börekçi, Bünyamin; Akçay, Fatih; Süleyman, Halis (Mashhad Univ Med Sciences, 2014)Objective(s): This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/ reperfusion (I/ R) injury in diabetic rats and evaluated oxidant and antioxidant marker ... -
Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Süleyman, Bahadır; Albayrak, Fatih; Akçay, Fatih (2012)Background: Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and thiamine pyrophosphate, whose antioxidant activity is known, have protective ... -
A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ... -
A comparative investigation of the nephrotoxic effects of various antihypertensive drugs in rats: biochemical and histopathological analysis
Malkoç, İsmail; Altunkaynak, Konca; Turan, Mehmet İbrahim; Gürsan, Nesrin; Hacımüftüoğlu, Ahmet; Akçay, Fatih; Üçüncü, Yılmaz; Süleyman, Halis (Carbone Editore, 2014)Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether ... -
Comparative review of biochemistry and cell anatomy of the hepatic tissue in rats administered some anti hypertensive drug for a long time
Malkoç, İsmail; Çetin, Nihal; Altuner, Durdu; Hacımüftüoğlu, Ahmet; Gürsan, Nesrin; Bakan, Ebubekir; Akçay, Fatih; Süleyman, Halis (2012)The adverse biochemical and structural effects of antihypertensive drugs over a long period (clonidine, methyldopa, rilmenidine, amlodipine, ramipril) on hepatic tissue has been examined in this study. The results are ... -
Examination of the effects of thiamine and thiamine pyrophosphate on doxorubicin-induced experimental cardiotoxicity
Polat, Bülent; Süleyman, Halis; Şener, Ebru; Akçay, Fatih (Sage Publications Inc, 2015)Background and Purpose: To investigate the effect of thiamine and thiamine pyrophosphate on doxorubicin-induced cardiotoxicity biochemically and histopathologically and to examine whether doxorubicin cardiotoxicity is ... -
The investigation of damage in the muscle tissue with the oxidant/antioxidant balance and the extent of postmortem DNA damage in rats
Öztürk, Cengiz; Şener, Mustafa Talip; Şener, Ebru; Yılmaz, İsmail; Akçay, Fatih; Süleyman, Halis (2013)The relationship of the extent of DNA damage and certain components of the oxidant/antioxidant balance in rat femoral muscle tissue with the post-mortem intervals was investigated and examined by making direct comparison ... -
The prevention of ischemia/reperfusion induced oxidative damage by venous blood in rabbit kidneys monitored with biochemical, histopatological and immunohistochemical analysis
Çetin, Nihal; Süleyman, Halis; Şener, Ebru; Demirci, Elif; Gündoğdu, Cemal; Akçay, Fatih (Polish Physiological Soc, 2014)The purpose of this study was to investigate the biochemical, histopathological and immunohistochemical effects of venous blood on ischemia/reperfusion-induced oxidative DNA damage and mutation in rabbit kidneys in comparison ... -
Protective effect of mirtazapine against cisplatin-induced oxidative stress and DNA damage in guinea pig ear
Kuduban, Ozan; Kucur, Cüneyt; Üçüncü, Harun; Şener, Ebru; Süleyman, Halis; Akçay, Fatih (Scientific Publishers India, 2014)Cisplatin ototoxicity is a major dose-limiting factor in the treatment of several neoplastic diseases. Oxidative stress might play an important role of pathogenesis of cisplatin ototoxicity. the aim of this study was to ...
