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Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil
Erik, İshak; Bozdal, Gözde; Şener, Sıla Özlem; Korkmaz, Büşra; Karaoğlu, Şengül Alpay; Terzioğlu, Salih; Yaylı, Nurettin (TUBITAK, 2022)The essential oil (EO) of Cota tinctoria var. tinctoria was analyzed using GC-FID / MS. A total of 51 compounds were determined from this taxon, accounting for 99.79% in hydrodistillation. Monoterpenes were the primary ... -
Comprehensive analysis of hedysarum nitidum: identification phytochemical contents, antioxidant potential, antimicrobial properties, cytotoxic effects, and enzyme inhibition activities
Baltürk, Nuray; Badem, Merve; Kanbolat, Şeyda; Yıldırım, Sercan; Şen, Tuğba Mazlum; Bozdal, Gözde; Yalçın, Can Özgür; Kandemir, Ali; Korkmaz, Nuriye; Karaoğlu, Şengül Alpay; Aliyazıcıoğlu, Rezzan (Wiley, 2025)Hedysarum species play a crucial agronomic role due to their high feed quality and ability to enhance soil fertility through nitrogen fixation. Traditionally, they have been used in medicine to boost energy, support the ... -
Dihydroisocoumarins and phenylglycosides from scorzonera longiana, their antimicrobial activities and molecular docking studies
Korkmaz, Büşra; Renda, Gülin; Bozdal, Gözde; Coşkunçelebi, Kamil; Bozdeveci, Arif; Uzuner, Uğur; Yaylı, Nurettin (Wiley, 2023)Five new phenyl dihydroisocoumarin glycosides (1-5) and two known compounds (6-7) were identified from the butanol fraction of Scorzonera longiana. The structures of 1-7 were elucidated based on spectroscopic methods. ... -
Synthesis, antimicrobial activities, and molecular modeling studies of agents for the sortase a enzyme
Tatar Yılmaz, Gizem; Yaylı, Nurettin; Tüzüner, Tamer; Bozdal, Gözde; Salmanlı, Merve; Renda, Gülin; Korkmaz, Büşra; Bozdeveci, Arif; Alpay Karaoğlu, Şengül (Wiley, 2024)Sortase A (SrtA) is an attractive target for developing new anti-infective drugs that aim to interfere with essential virulence mechanisms, such as adhesion to host cells and biofilm formation. Herein, twenty hydroxy, ...