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Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil
Erik, İshak; Bozdal, Gözde; Şener, Sıla Özlem; Korkmaz, Büşra; Karaoğlu, Şengül Alpay; Terzioğlu, Salih; Yaylı, Nurettin (TUBITAK, 2022)The essential oil (EO) of Cota tinctoria var. tinctoria was analyzed using GC-FID / MS. A total of 51 compounds were determined from this taxon, accounting for 99.79% in hydrodistillation. Monoterpenes were the primary ... -
Dihydroisocoumarins and phenylglycosides from scorzonera longiana, their antimicrobial activities and molecular docking studies
Korkmaz, Büşra; Renda, Gülin; Bozdal, Gözde; Coşkunçelebi, Kamil; Bozdeveci, Arif; Uzuner, Uğur; Yaylı, Nurettin (Wiley, 2023)Five new phenyl dihydroisocoumarin glycosides (1-5) and two known compounds (6-7) were identified from the butanol fraction of Scorzonera longiana. The structures of 1-7 were elucidated based on spectroscopic methods. ... -
Synthesis, antimicrobial activities, and molecular modeling studies of agents for the sortase a enzyme
Tatar Yılmaz, Gizem; Yaylı, Nurettin; Tüzüner, Tamer; Bozdal, Gözde; Salmanlı, Merve; Renda, Gülin; Korkmaz, Büşra; Bozdeveci, Arif; Alpay Karaoğlu, Şengül (Wiley, 2024)Sortase A (SrtA) is an attractive target for developing new anti-infective drugs that aim to interfere with essential virulence mechanisms, such as adhesion to host cells and biofilm formation. Herein, twenty hydroxy, ...