Yazar "Burmaoğlu, Serdar" için listeleme
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Design, synthesis and biological evaluation of novel bischalcone derivatives as potential anticancer agents
Burmaoğlu, Serdar; Göbek, Arzu; Aydın, Büşra Öztürk; Yurtoğlu, Emine; Aydın, Büşra Nur; Yalçın Özkat, Gözde; Hepokur, Ceylan; Şimşek Özek, Nihal; Ayşin, Ferhunde; Altuntaş, Ramazan; Algül, Öztekin (Elsevier, 2021)Building on our previous work that discovered chalcone as a promising pharmacophore for anticancer activity, we have various other chalcone derivatives and have synthesized a series of novel bischalcone to explore their ... -
Design, synthesis, and computational studies of benzimidazole derivatives as new antitubercular agents
Yalçın Özkat, Gözde; Ersan, Ronak H.; Ülger, Mahmut; Ülger, Seda T.; Burmaoğlu, Serdar; Yıldız, İlkay; Algül, Öztekin (Taylor & Francis Ltd., 2022)The increase in the drug-resistant strains of Mycobacterium tuberculosis has led researchers to new drug targets. The development of new compounds that have effective inhibitory properties with the selective vital structure ... -
Synthesis, molecular docking and some metabolic enzyme inhibition properties of biphenyl-substituted chalcone derivatives
Burmaoğlu, Serdar; Kazancıoğlu, Elif Akın; Kazancıoğlu, Mustafa Z.; Sağlamtaş, Rüya; Yalçın Özkat, Gözde; Gülçin, İlhami; Algül, Öztekin (Elsevier, 2022)The new synthesized biphenyl-substituted chalcone derivatives were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes. ...
