Yazar "Ceylan, Şule" için listeleme
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Antibacterial and antioxidant activities of traditional medicinal plants from the Erzurum region of Turkey
Ceylan, Şule; Çetin, Serkan; Camadan, Yasemin; Saral, Özlem; Özsen, Özge; Tutuş, Ahmet (Springer London Ltd, 2019)Background in this study, 13 different extracts were investigated which are grown in the region of Erzurum. Objective the aim of this study was to screen various plant extracts that are known and used for medicinal purposes ... -
Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus
Bektaş, Hakan; Ceylan, Şule; Demirbaş, Neslihan; Alpay-Karaoğlu, Şengül; Sökmen, Bahar Bilgin (Birkhauser Boston, 2013)2-[6-(Morpholin-4-yl)pyridin-3-ylamino]acetohydrazide (4) was obtained starting from 6-morpholin-4-ylpyridin-3-amine (2) via the formation of ester (3) and then converted to the corresponding Schiff bases (5, 6) with the ... -
Chemical composition of essential oil by SPME and evaluation of antimicrobial, antioxidant activities of Quercus inectoria gall
Ceylan, Şule; Yardımcı, Şehmuz Semih; Camadan, Yasemin; Saral, Özlem; Batur, Özge Özsen (University of Life Sciences in Lublin, 2021)Quercus infectoria galls have been utilized to cure widespread illnesses. In line with it, this paper aims to investigate the chemical combination of the volatile oils obtained from galls of Q. infectoria and evaluate their ... -
Chemical composition, antimicrobial, and antioxidant activities of medicinal plants nutsedge and fenugreek
Ceylan, Şule; Camadan, Yasemin; Saral, Özlem; Batur, Özge Özsen (North Carolina State University, 2022)Purple nutsedge roots (Cyperus rotundus L.) and fenugreek seeds (Trigonella foenum-graecum L.) have been traditionally used as food and to treat common ailments. After extraction by solid-phase microextraction (SPME), the ... -
Conventional and microwave irradiated synthesis, biological activity evaluation of highly substituted indole-triazole hybrids
Cebeci, Yıldız Uygun; Ceylan, Şule; Karaoğlu, Şengül Alpay (Elsevier, 2022)In the present study, a series of new indole-3-carbaldehyde embedded triazole derivatives have been synthesized. 4-{[(1E)-1H-indol-3-ylmethylidene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) were converted to ... -
Conventional and microwave-assisted synthesis of novel 1,2,4-triazole derivatives containing tryptamine skeleton and evaluation of antimicrobial activity
Cebeci, Yıldız Uygun; Ceylan, Şule; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Bentham Science Publishing, 2021)1,2,4-Triazole-3-one (3) obtained from tryptamine was transformed to the corresponding carbox(thio)amides via several steps (6a-d). Their reaction with sodium hydroxide performed the 1,2,4triazole derivatives (7a-d). ... -
An efficient microwave-assisted synthesis of novel quinolone-triazole and conazole-triazole hybrid derivatives as antimicrobial and anticancer agents
Cebeci, Yıldız Uygun; Ceylan, Şule; Karaoğlu, Şengül Alpay; Altun, Muhammed (Wiley, 2022)1,2,4-Triazole-fluoroquinolone and 1,2,4-triazole-conazole hybrids are designed, synthesized, and investigated in vitro against a variety of common diseases. The structure of the newly synthesized compounds are characterized ... -
Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
Ceylan, Şule; Bayrak, Hacer; ÖZdemir, Serap Başoğlu; Uygun, Yıldız; Mermer, Arif; Demirbaş, Neslihan; Ülker, Serdar (Walter de Gruyter Gmbh, 2016)Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl) ethanone. Treatment of 4a,b with base afforded ... -
Microwave-assisted synthesis of novel mannich base and conazole derivatives containing biologically active pharmacological groups
Cebeci, Yıldız Uygun; Ceylan, Şule; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay (Bentham Science Publishers, 2021)Background: The aim of this study was to synthesize new Mannich bases and conazol derivatives with biological activity by the microwave-assisted method. Introduction: 1,2,4-Triazole-3-one (3) acquired from tryptamine was ... -
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
Ceylan, Şule; Bayrak, Hacer; Özdemir, Serap Başoğlu; Uygun, Yıldız; Mermer, Arif; Demirbaş, Neslihan; Ülker, Serdar (Bentham Science Publ Ltd, 2016)Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. the acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ... -
Syntheses and biological activities of new hybrid molecules containing different heterocyclic moieties
Ceylan, Şule; Bektaş, Hakan; Bayrak, Hacer; Demirbaş, Neslihan; Karaoğlu, Şengül Alpay; Ülker, Serdar (Wiley, 2013)4-Aryl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-(thi)oles 5-7, obtained starting from nicotinic acid hydrazide were converted to the corresponding Mannich bases 12-24 by the reaction with several heterocyclic amines in the ... -
Synthesis and antimicrobial activity of new piperazine-based heterocyclic compounds
Özdemir, Serap Başoğlu; Cebeci, Yıldız Uygun; Bayrak, Hacer; Mermer, Arif; Ceylan, Şule; Demirbaş, Ahmet; Karaoğlu, Şengül Alpay; Demirbaş, Neslihan (Walter de Gruyter Gmbh, 2017)The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. the synthesis of conazole analogs 10a-f ... -
Synthesis and antimicrobial, antiproliferative evaluation of novel quinolone and conazole analogues via conventional and microwave techniques
Ceylan, Şule; Cebeci, Yıldız Uygun; Karaoğlu, Şengül Alpay; Altun, Muhammed (Wiley, 2021)1,2,4-Triazole-3-one (3), acquired from cinnamaldehyde was converted to the corresponding carbox(thio)amides via several steps (6 a-c). Their reaction with sodium hydroxide gave the 1,2,4-triazole derivatives (7 a-c). ... -
Synthesis and characterization of some azole derivatives as potential biological and anticancer agents
Uygun Cebeci, Yıldız; Ceylan, Şule; Altun, Muhammed; Karaoğlu, Şengül Alpay (Wiley, 2023)The treatment of 4-{[(1E)-(2,4-dichlorophenyl)methylene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (2) was synthesized from 4-amino-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (1). Then ethyl (4-{[(1E)-(2,4-dichl ... -
Synthesis of some new hybride molecules containing several azole moieties and investigation of their biological activities
Ceylan, Şule; Bayrak, Hacer; Demirbaş, Ahmet; Ülker, Serdar; Alpay-Karaoğlu, Şengül; Demirbaş, Neslihan (Maik Nauka/Interperiodica/Springer, 2014)1,2,4-Triazole-3-one prepared from tryptamine was converted to the corresponding carbothioamides by several steps. Their treatment with ethyl bromoacetate or 4-chlorophenacyl bromide produced the corresponding 5-oxo-1,3- ... -
Yaban mersininin (Vaccinium myrtillus L.) farklı çözücü ekstraktlarındaki antioksidan ve antimikrobiyal aktivitelerinin belirlenmesi
Ceylan, Şule; Saral, Özlem; Özcan, Mehmet; Harşıt, Burhan (2017)Bu çalışmada Giresun ilinde yetişen yaban mersininin (Vaccinium myrtillus L.) meyve ve yaprağı, hem yaş hem de kurutulmuş halinin dört farklı çözücüdeki ekstraktları (etanol, aseton, su ve dietil eter) ayrı ayrı incelenmiştir. ...
