Yazar "Demiryılmaz, İsmail" için listeleme
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Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Süleyman, Bahadır; Albayrak, Fatih; Akçay, Fatih (2012)Background: Oxidative liver injury occurring with methotrexate restricts its use in the desired dose. Therefore, whether or not thiamine and thiamine pyrophosphate, whose antioxidant activity is known, have protective ... -
A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ... -
Damage induced by paracetamol compared with N-acetylcysteine
Kısaoğlu, Abdullah; Özoğul, Bünyamin; Turan, Mehmet İbrahim; Yılmaz, İsmail; Demiryılmaz, İsmail; Atamanalp, Sabri Selçuk; Bakan, Ebubekir; Süleyman, Halis (Lippincott Williams & Wilkins, 2014)Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol. Methods: Rats for this experiment were divided into the following groups: ... -
The effect of hippophae rhamnoides extract on oxidative damage on rat's gastric tissue depending on Co-implementation of methotrexate and indomethacin
Yılmaz, İsmayıl; Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Üçüncü, Yılmaz; Altuner, Durdu; Kurt, Nezahat; Kunak, Semih C.; Kısaoğlu, Abdullah; Özoğul, Bünyamin; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2014)The effect of Hippophae rhamnoides (HR) extract on oxidative damage on rat's gastric tissue depending on co-implementation of methotrexate (MTX) and indomethacin (IND) was investigated biochemically and histopathologically. ... -
Effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate in rats
Demiryılmaz, İsmail; Uzkeser, Hülya; Çetin, Nihal; Hacımüftüoğlu, Ahmet; Bakan, Ebubekir; Altuner, Durdu (Chemical Publishing Co., 2013)In this study, effect of mirtazapine on gastric oxidative stress and DNA injury created with methotrexate was investigated. Experimental results showed that GSH (nmol/g protein), MDA (?mol/g protein) and MPO (?/g protein) ... -
Effect of thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat kidney
Altuner, Durdu; Çetin, Nihal; Süleyman, Bahadır; Aslan, Zeynep; Hacımuftuoğlu, Ahmet; Gülaboğlu, Mine; İsaoğlu, Neslihan; Demiryılmaz, İsmail; Suleyman, Halis (Wolters Kluwer Medknow Publications, 2013)Objectives: the biochemical effects of thiamine pyrophosphate on ischemia-reperfusion (IR) induced oxidative damage and DNA mutation in rat kidney tissue were investigated, and compared to thiamine. Materials and Methods: ... -
Effects of Hypericum perforatum and Hippophae rhamnoides extracts on indomethacin-induced gastric oxidative stress in rats
Turan, Mehmet İbrahim; Bilen, Habib; Demiryılmaz, İsmail; Özgeriş, Fatma Betül; Baykal, Hüseyin; Türkoğlu, Murat; Süleyman, Halis (Allied Acad, 2013)We investigate the effects of Hypericum perforatum (HP) and Hippophae rhamnoides (HR) extracts on indomethacin-induced gastric injury. Rats were divided into five groups each containing 10 animals. the first group received ... -
The effects of thiamine and thiamine pyrophosphate on alcohol-induced hepatic damage biomarkers in rats
Yılmaz, İsmayil; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Çetin, Nihal; Gül, Mehmet Ali; Süleyman, Halis (Verduci Publisher, 2015)OBJECTIVE: This study examined the effects of thiamine and thiamine pyrophosphate on oxidative damage developing in association with hepatic injury caused by alcohol toxicity in rats and on hepatic injury markers. MATERIALS ... -
The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide
İsaoğlu, Ünal; Yılmaz, Mehmet; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Bilen, Habib; Yapca, Ömer Erkan; Demiryılmaz, İsmail; İsaoğlu, Neslihan; Gül, Mehmet Ali; Kumbasar, Serkan; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2012)The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: ... -
Investigation and histopathological evaluation of the effects of omeprazole on the ischemia-reperfusion induced oxidative damage and DNA mutation in rat ovarian tissue
Demiryılmaz, İsmail; Çetin, Nihal; Yapca, Ömer Erkan; Altuner, Durdu; İsaoğlu, Ünal; Özgeris, Fatma Betül; Çalık, Muhammet; Süleyman, Halis (Chemical Publishing Co., 2013)In this study, the biochemical and histopathological effects of omeprazole on ischemia-reperfusion (I/R) induced oxidative damage in rat ovarian tissue were investigated. The moment that the animals remained motionless in ... -
The protective effect of melatonin and agomelatin against cisplatin-induced nephrotoxicity and oxidative stress in the rat kidney
Yılmaz, İsmayıl; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Süleyman, Bahadır; Turan, Işıl Şiltelioğlu; Altuner, Durdu; Hakan, Alp Hamit; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2013)Cisplatin is used to treat various types of cancers. Its use is limited, however, due to nephrotoxicity, which may result from free radical damage. Evidence exists that melatonin reduces oxidative stress-induced damage. ... -
Protective effect of nimesulide against hepatic ischemia/reperfusion injury in rats: Effects on oxidant/antioxidants, DNA mutation and COX-1/COX-2 levels
Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Kısaoğlu, Abdullah; Gülaboğlu, Mine; Yılmaz, İsmayil; Süleyman, Halis (Polish Acad Sciences Inst Pharmacology, 2014)Background: Nimesulide is a pharmacological agent and selective COX-2 inhibitor. It has anti-inflammatory, analgesic and antipyretic properties. the purpose of this study was to investigate the effect of nimesulide on ...
