Yazar "Güzel, Ali İrfan" için listeleme
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Are there fetal stem cells in the maternal brain?
Demirhan, Osman; Çekin, Necmi; Taştemir, Deniz; Tunç, Erdal; Güzel, Ali İrfan; Meral, Demet; Demirbek, Bülent (Wolters Kluwer Medknow Publications, 2013)Fetal cells can enter maternal blood during pregnancy but whether they can also cross the blood-brain barrier to enter the maternal brain remains poorly understood. Previous results suggest that fetal cells are summoned ... -
Association of paraoxonase-1 L55M and Q192R polymorphisms with PCOS risk and potential risk factors for atherosclerosis
Nalkıran, Hatice Sevim; Şahin, Serap Baydur; Ayaz, Teslime; Nalkıran, İhsan; Güzel, Ali İrfan; Eldeş, Tuğba; Yıldız, Yasin (Future Medicine Ltd, 2019)Aim: To examine the PON1-L55M and-Q192R polymorphisms for polycystic ovary syndrome (PCOS) risk in relation with atherosclerosis risk markers. Methods: Blood samples were collected from 203 women (PCOS [n = 151], control ... -
Chromosomal findings and sequence analysis of target exons of calcium-sensing receptor (CaSR) gene in patients with Sagliker syndrome
Tunç, Erdal; Demirhan, Osman; Sağlıker, Yahya; Yıldız, İsmail; Paylar, Nuray; Güzel, Ali İrfan (2017)Background/aim: Sagliker syndrome (SS) develops as a continuation of chronic kidney disease and secondary hyperparathyroidism conditions. It was thought that there are some genetic predisposition factors leading to SS. The ... -
Clodronate changes neurobiological effects of pulsed magnetic field on diabetic rats with peripheral neuropathy
Mert, Tufan; Öçal, Işıl; Güzel, Ali İrfan; Günay, İsmail (Taylor & Francis Ltd., 2013)Several studies have reported that pulsed magnetic fields (PMFs) can be a choice of therapy for diabetic peripheral neuropathy. However, the exact underlying mechanism of PMF is still not known. The purpose of this study ... -
Cloning and expression of ?-1,3-glucanase gene from Cellulosimicrobium cellulans in Escherichia coli DH5?
Bu çalışmada Cellulosimicrobium cellulans bakterisine ait ?-1,3-glukanaz geni PCR ile amplifiye edilerek pUC18 klonlama vektörüne klonlanmış, böylece pTEG5 ve pTEG11 rekombinant plazmit DNA’lar elde edilmiştir. Rekombinant ... -
Cloning and expression of beta-1,3-glucanase gene from cellulosimicrobium cellulans in escherichia coli DH5a
Özcan, Bahri Devrim; Özcan, Numan; Baylan, Makbule; Güzel, Ali İrfan (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)In this study, beta-1,3-glucanase gene of Cellulosimicrobium cellulans was amplified by PCR and cloned in pUC18 cloning vector to construct the recombinant plasmids pTEG5 and pTEG11. the recombinant plasmids pTEG5 and ... -
Cloning and expression of cellulosimicrobium cellulans ?-1,3-glucanase gene in lactobacillus plantarum to create new silage inoculant for aerobic stability
Bu çalışmada, rekombinant pTEG5 plazmit DNA’sına (pUC18 + Cellulosimicrobium cellulans’ın ?-1,3-glukanaz geni) pLP3537 plazmitinin p353-2 kriptik plazmit bölgesinin aktarılması ile rekombinant pTE353-?G plazmit DNA’sı ... -
Cloning and expression of cellulosimicrobium cellulans beta-1,3-glucanase gene in lactobacillus plantarum to create new silage inoculant for aerobic stability
Özcan, Bahri Devrim; Özcan, Numan; Baylan, Makbule; Güzel, Ali İrfan (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)In this study, the recombinant plasmid pTE353-beta G was created by inserting the p353-2 cryptic plasmid region of pLP3537 into pTEG5 recombinant plasmid contains pUC18 and beta-1,3-glucanase gene of Cellulosimicrobium ... -
Comparison of DNA isolation methods from mammalian sperm cells and development of a new protocol
Nalkıran, Hatice Sevim; Nalkıran, İhsan; Rakıcı, Sema Yılmaz; Tümkaya, Levent; Güzel, Ali İrfan (Effect Publishing Agency ( EPA ), 2021)Sperm DNA tightly packed with protamines makes the DNA isolation procedure from sperm cells long and laborious. Cell lysis is also a challenging step because of the disulfide bonds-rich membranes of the sperm cells. In ... -
Cytogenetic and molecular investigation in children with possible fragile X syndrome
Özer, Onur; Demirhan, Osman; Tunç, Erdal; Bağcı, Hüseyin; Karahan, Dilara; Tanrıerdi, Nilgün; Yılmaz, Bertan; Güzel, Ali İrfan; Keser, İbrahim (2012)Amaç: Kalıtımla geçen mental retardasyonun en yaygın nedeni Frajil X sendromudur (FXS). X kromozomu üzerinde bulunan FMR1 geninde meydana gelen bir mutasyon, bu sendroma yol açmaktadır. Tanı için kromozom analizi ve moleküler ... -
Determination of genotypic and phenotypic characteristics of friedreich's ataxia and autosomal dominant spinocerebellar ataxia types 1, 2, 3, and 6
Boz, Pınar Bengi; Koç, Filiz; Sel, Sabriye Kocatürk; Güzel, Ali İrfan; Kasap, Halil (Aves, 2016)Introduction: This study aimed to analyze the genotypic characteristics of Friedreich's ataxia (FA) and autosomal dominant ataxias [such as spinocerebellar ataxia (SCA) types 1, 2, 3, and 6] using molecular and biological ... -
Effect of conception time and maternal age upon fetal sex ratio in Çukurova population
Tunç, Erdal; Demirhan, Osman; Pazarbaşı, Ayfer; Korkmaz, Deniz Taştemir; Güzel, Ali İrfan; Kasap, Mülkiye; Tuncay Özgünen, Fatma; Yılmaz, Bertan; Kocatürk-Sel, Sabriye (2014)Amaç: Bu çalışmanın amacı, Çukurova ve çevresindeki populasyonda konsepsiyon ayı, ebevynlerin yaşları, mevsimsel değişimler, ebevynlerin alkol ve sigara kullanım durumları gibi çevresel değişkenlerin fetal cinsiyet oranını ... -
The first report described as an important study: The association of mannose-binding lectin gene 2 polymorphisms in children with down syndrome
Background: Mannose-binding lectin gene 2 (MBL2) plays a very important role in the first line of host immune response in Down syndrome (DS). The importance of MBL2 gene polymorphisms in children with DS is unclear, and ... -
Freidreich ataksisi ve spinoserebellar ataksi tip 1, 2, 3 ve 6’nın genotipik ve fenotipik özellikleri
Amaç: Bu çalışmada klinik, elektrofizyolojik bulgular ışığında herediter ataksi olarak değerlendirilen olguların moleküler genetik incelemeleri de dikkate alınarak Freidreich Ataksisi (FA) ve otozomal dominant Spino ... -
Gelişmekte olan fare fetüs beyninde aromataz, östrojen reseptör alfa ve progesteron reseptörünün birbirleriyle olan ilişkileri
Yılmaz, Mehmet Bertan; Erkoç, M. Ali; Kocatürk, Sabriye Sel; Tunç, Erdal; Özpak, Lütfiye; Pazarbaşı, Ayfer; Güzel, Ali İrfan; Alptekin, Davut; Lüleyap, H. Ümit; Demirhan, Osman; Kasap, Mülkiye; Kasap, Halil (2013)Amaç: Bu çalışmadaki amacımız, gonodotropin salgılanması, cinsel dimorfik fetal beyin gelişimi ve yetişkinlerdeki cinsel tercih için çok önemli olan, aromatazın ve östrojen reseptör alfa (Esr1) ve progesteron reseptörlerinin ... -
Genetic variations in OLR1 gene associated with PCOS and atherosclerotic risk factors
Şahin, Serap Baydur; Nalkıran, İhsan; Ayaz, Teslime; Güzel, Ali İrfan; Eldeş, Tuğba; Calapoğlu, Tuğba; Nalkıran, Hatice Sevim (Sage Publications, 2023)Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. The aim of this study was to investigate the association of oxidized low-density lipoprotein receptor 1 (OLR1) gene variations ... -
Investigation of the polymorphism of the myostatin gene by using PCR-RFLP in two tilapia species (Oreochromis aureus and oreochromis niloticus)
Baylan, Makbule; Mazi, Gamze; Özcan, Numan; Özcan, Bahri Devrim; Güzel, Ali İrfan (WFL Publisher Ltd., 2015)The aim of the study was to investigate the restriction fragment length polymorphism (RFLP) of the exon 1–3 fragments from the myostatin gene in two tilapia species, Oreochromis aureus and Oreochromis niloticus. Tissue ... -
Pelvic radiation-induced testicular damage: an experimental study at 1 gray
Rakıcı, Sema Yılmaz; Güzel, Ali İrfan; Tümkaya, Levent; Nalkıran, Hatice Sevim; Mercantepe, Tolga (Taylor & Francis Inc, 2020)Therapeutic radiation of the pelvic region has been shown to cause damage to testicular germ cells. in this study we aimed to evaluate the effects of a low therapeutic dose of 1 Gy on the induction of cellular and histological ... -
Rapid detection of fetal aneuploidies by quantitative fluorescent- polymerase chain reaction for prenatal diagnosis in the turkish population
Güzel, Ali İrfan; Yilmaz, M.B.; Demirhan, O.; Pazarbasi, A.; Kocaturk-Sel, S.; Erkoc, M.A.; Sariturk, C. (0-Belirlenecek, 2012)Prenatal diagnosis is testing for diseases or conditions in a fetus or embryo before it is born. It employs a variety of techniques to determine the health and condition of an unborn fetus. The main goal of this process ... -
The reliability of maternal serum triple test in prenatal diagnosis of fetal chromosomal abnormalities of pregnant Turkish women
Demirhan, Osman; Pazarbaşı, Ayfer; Güzel, Ali İrfan; Taştemir, Deniz; Yılmaz, Bertan; Kasap, Mülkiye; Özgünen, Fatma Tuncay; Evrüke, Cüneyt; Demir, Cansun; Tunç, Erdal; Kocatürk-Sel, Sabriye; Onatoǧlu-Aríkan, Dilge (2011)Aim: The purpose of this article was to evaluate the reliability of maternal serum triple marker screening of alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol for the prenatal diagnosis of fetal ...
