Yazar "Kukula, Osman" için listeleme
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Effect of thiamine pyrophosphate on oxidative damage to the oropharyngeal, nasal and cochlear tissues induced by doxorubicin in guinea pigs
Erhan, Ertuğrul; Turan, Fatih; Terzi, Suat; Çeliker, Metin; Mammadov, Renad; Malkoç, İsmail; Kukula, Osman; Çankaya, Murat (Colegio Farmaceuticos Provincia de Buenos Aires, 2017)Doxorubicin (DOX) inhibits the enzyme tyaminpyrophosphokinase (TPK). Hence the synthesis of thiamine pyrophosphate (TPP) which is the active metabolite of thiamine stops. This leads to oxidative damage. in the literature, ...
