Yazar "Metintaş, Muzaffer" için listeleme
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Akciğer kanserli hastalarda plazma dna metiltransferaz ve metil- CpG'ye bağlanan protein seviyelerinin değerlendirilmesi
Özbayer, Cansu; Üstüner, Derya Akyıldız; Ak, Güntülü Akdoğan; Saydam, Faruk; Metintaş, Muzaffer; Değirmenci, İrfan (2017)Amaç: Akciğer kanseri, akciğer doku hücrelerinin kontrolsüz çoğalmasıyla oluşan ölümcül bir hastalıktır. Çevresel faktörlerle birlikte genetik ve epigenetik değişikliklerin kanser gelişimine neden olduğu bilinmektedir. DNA ... -
Common variants rs3815188 and rs1043994 on notch3 gene confer susceptibility to lung cancer: A hospital-based case-control study
Yağcı, Emine; Değirmenci, İrfan; Özbayer, Cansu; Ak, Güntulu; Saydam, Faruk; Metintaş, Muzaffer (Begell House Inc, 2019)The Notch signaling pathway is a mechanism that plays a role in the determination of cell fate during cell development. Signals between neighbor cells are amplified through the Notch receptors. Notch activity is related ... -
Expression and potential role of miR200b and miR1274a in lung cancer patients
Özbayer, Cansu; Ak, Güntulu Akdoğan; Üstüner, Derya; Saydam, Faruk; Güneş, Hasan Veysi; Metintaş, Muzaffer (Derman Medical Publ, 2017)Aim: Lung cancer (LC) is a fatal disease characterized by uncontrolled proliferation of airway epithelial cells and caused by genetic or environmental factors. LC is one of the most common types of cancer and the leading ... -
miRSNPs of miR1274 and miR3202 genes that target MeCP2 and DNMT3b are associated with lung cancer risk: A study conducted on MassARRAY genotyping
Özbayer, Cansu; Değirmenci, İrfan; Üstüner, Derya; Ak, Güntulu; Saydam, Faruk; Çolak, Ertuğrul; Güneş, Hasan Veysi; Metintaş, Muzaffer (Begell House Inc, 2016)Genetic variants of miRNAs that target DNMTs and MBDs involved in DNA methylation were scanned with current databases, and 35 miRSNPs in 22 miRNA genes were identified. the aim of the study was to determine the association ...
