Yazar "Sümer, Ayşegül" için listeleme
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Agomelatine reverses scopolamine-ınduced learning and memory impairment in adult rats
Saral, Sinan; Kaya, Ali Koray; Topçu, Atilla; Öztürk, Aykut; Sümer, Ayşegül; Pınarbaş, Esra (Sakarya Üniversitesi, 2021)Amaç: Agomelatin, melatonin reseptör (MT1 ve MT2) agonisti ve serotonin reseptör (5-HT2C) antagonisti olan antidepresan bir ilaçtır. Artan kanıtlar, agomelatinin nöroprotektif ve nöromodülatör etkiye sahip olduğunu ... -
Apelin-13 increased food intake with serum ghrelin and leptin levels in male rats
Saral, Sinan; Alkanat, Mehmet; Sümer, Ayşegül; Canpolat, Sinan (Comenius Univ, 2018)In this study, we aimed to explain the role of apelin-13 on body weight, food and water intake with serum leptin, ghrelin, neuropeptid Y (NPY) and peptid YY (PYY) levels in male rat. Thirty-two Sprague-Dawley male rats ... -
Assessment of some biochemistry parameters in hospitalized patients evaluated with CT and RT-PCR for the diagnosis of Covid-19
Sümer, Ayşegül; Uzun, Lütfiye Nur (2022)It was reported that a new type of coronavirus (2019-nCoV) was the cause of repeated pneumonia cases in Wuhan, Hubei Province, China in December 2019. The aim of this study was to evaluate the laboratory results of the ... -
Autoantibodies against carbonic anhydrase I and II in patients with acute myeloid leukemia
Menteşe, Ahmet; Erkut, Nergiz; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Doğramacı, Şeniz; Alver, Ahmet; Sönmez, Mehmet (2017)Amaç: Kanser, dünyadaki başlıca ölüm nedenlerinden birisi olup, küresel bir toplum sağlığı sorunudur. Organizmanın kendi antijenlerine karşı gelişen otoantikorlar pek çok kanser hastasının serumunda tespit edilmiştir. Son ... -
Carbonic anhydrase I and II autoantibodies in Behcet's disease
Mentese, Ahmet; Alver, Ahmet; Demir, Selim; Sümer, Ayşegül; Özer Yaman, Serap; Karkucak, Murat; Aydın Çapkın, Arzu; Us Altay, Diler; Turan, İbrahim (Publisaude-Edicoes Medicas Lda, 2017)Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a ... -
Chronic restraint stress impairs spatial memory while decreasing hippocampal BDNF levels in rats
Saral, Sinan; Sümer, Ayşegül; Kaya, Ali Koray; Öztürk, Aykut; Topçu, Atilla (İnönü Üniversitesi Tıp Fakültesi, 2022)Aim: This study investigated the potential role of chronic restraint stress (CRS) on spatial memory, recognition memory, brain-derived neurotrophic factor (BDNF) and acetylcholine (ACh) levels in young adult rats. Material ... -
Circulating parameters of oxidative stress and hypoxia in normal pregnancy and HELLP syndrome
Menteşe, Ahmet; Güven, Süleyman; Demir, Selim; Sümer, Ayşegül; Yaman, Serap Özer; Alver, Ahmet; Karahan, Süleyman Caner (Wroclaw Medical Univ, 2018)Background. the HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets) is a complication of severe pre-eclampsia, a condition characterized by oxidative stress elevation caused by disequilibrium between lipid ... -
Detection of autoantibodies against carbonic anhydrase I and II in the plasma of patients with gastric cancer
Menteşe, Ahmet; Fidan, Evren; Alver, Ahmet; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Fidan, Sami; Kavgacı, Halil; Turan, İbrahim (Termedia Publishing House Ltd, 2017)Cancer is the second leading cause of death and gastric cancer is the fourth most common cancer type worldwide. Investigation of autoantibodies in cancer patients has been a popular research area in recent years. the aim ... -
The effect of bee pollen on reproductive and biochemical parameters in methotrexate-induced testicular damage in adult rats
Saral, Özlem; Dokumacıoğlu, Eda; Saral, Sinan; Sümer, Ayşegül; Bulmuş, Özgür; Kaya, Şeyma Özer; Canpolat, Sinan (De Gruyter Open Ltd., 2021)Objectives: Methotrexate (MTX) is an anticancer drug used in chemotherapy. MTX was known for its toxic effects involving most of the organs including testis. Bee pollen is healthy food for human and has antioxidant effect. ... -
The effects of apelin on myometrium contractions in pregnant rats
Kaçar, Emine; Ercan, Zübeyde; Serhatlıoğlu, İhsan; Sümer, Ayşegül; Keleştimur, Haluk; Kutlu, Selim (C M B Assoc, 2018)Apelin, which is a new hormone, is secreted especially in the brain by hypothalamus as well as by many other organs like the stomach, fat tissue, and the heart. For apelin, whose possible effects on many bodily functions ... -
Effects of homocysteine on adipocyte differentiation and CD36 gene expression in 3T3-L1 adipocytes
Menteşe, Ahmet; Alver, Ahmet; Sümer, Ayşegül; Demir, Selim (Springer, 2016)The aim of this study was to investigate the effects of homocysteine (Hcy), a risk factor for cardiovascular diseases, hypertension, stroke and obesity, on expression of CD36 that regulates uptake of oxidized low-density ... -
Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes
Sümer, Ayşegül; Keha, Eşref Edip; Menteşe, Ahmet; Alver, Ahmet (De Gruyter, 2020)Background: Topiramate, an antiepileptic drug, besides its known effects in neurons, is a carbonic anhydrase inhibitor and causes weight loss in treated subjects, but, the mechanisms of weight loss effect have not been yet ... -
Nutrition improves COVID-19 clinical progress
Sümer, Ayşegül; Uzun, Lütfiye Nur; Özbek, Yağmur Demirel; Tok, Hümeyra Hançer; Altınsoy, Canan (Springer, 2022)Nutrition is a basic need and is crucial for the persistence of good health. This awareness has increased since December 2019 during the pandemic that the world is still facing. The importance of nutrition in infectious ... -
Serum carbonic anhydrase I and II autoantibodies in patients with chronic lymphocytic leukaemia
Menteşe, Ahmet; Erkut, Nergiz; Demir, Selim; Yaman, Serap Özer; Sümer, Ayşegül; Erdem, Mehmet; Alver, Ahmet; Sönmez, Mehmet Giray (Termedia Publishing House Ltd, 2018)Cancer is the second most important cause of mortality, and millions of people either have or have had the disease. Leukaemia is one of the most common forms of cancer. Autoantibodies that have developed against the ...
