Yazar "Samancı, Tuğba Çelik" için listeleme
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Biochemical and histopathological investigation of liver tissues on high fat diet fed rats
Samancı, Tuğba Çelik; Gökçimen, Alpaslan; Kuloğlu, Tuncay; Boyacıoğlu, Murat; Kuyucu, Yurdun; Polat, Sait (Galenos Yayıncılık, 2022)Objective: Hepatic steatosis is a common cause of liver disease and has become more prevalent recently. This study was conducted to investigate the biochemical and histopathological changes in the liver tissue high fat ... -
Effects of bone marrow-derived mesenchymal stem cells on doxorubicin-induced liver injury in rats
Samancı, Tuğba Çelik; Gökçimen, Alpaslan; Eren, Mehtap Kılıç; Gürses, Kadri Murat; Pilevneli, Hatice; Kuyucu, Yurdun (Wiley, 2022)Doxorubicin (DOX) is a potent chemotherapeutic agent and has toxic effects on various organs, including the liver. In the current study, we aimed to investigate the effects of bone-marrow-derived mesenchymal stem cell ... -
The effects of TNF-alpha inhibitors on carbon tetrachloride-induced nephrotoxicity
Özdemir, Ali; Tümkaya, Levent; Kalcan, Süleyman; Uyan, Mikail; Karakaya, Ahmet; Demiral, Gökhan; Samancı, Tuğba Çelik; Mercantepe, Tolga; Cüre, Medine Cumhur; Cüre, Erkan (Taylo & Francis Ltd., 2021)Objectives: Carbon tetrachloride (CCl4), employed in various industrial fields, can cause acute damage in renal tissues. This study investigated the therapeutic effect of the TNF-alpha inhibitor Infliximab on TGF-beta and ... -
Evaluation of the protective effect of coenzyme Q10 against x-ray irradiation-induced ovarian injury
Tekin, Yeşim Bayoğlu; Tümkaya, Levent; Mercantepe, Tolga; Topal, Zehra Suzan; Samancı, Tuğba Çelik; Yılmaz, Hülya Kılıç; Rakıcı, Sema Yılmaz; Topçu, Atilla (Wiley, 2024)Aim: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. Methods: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group ... -
The protective effects of ginseng on x-irradiation-induced intestinal damage in rats
Özdemir, Ali; Tümkaya, Levent; Mercantepe, Tolga; Samancı, Tuğba Çelik; Uyan, Mikail; Kalcan, Süleyman; Demiral, Gökhan; Pergel, Ahmet; Kutlu, Eda Yılmaz; Yılmaz, Hülya Kılıç (Springer, 2023)Although radiotherapy is widely employed in the treatment of various malignancies in oncology patients, its use is limited by the toxic effects it causes in surrounding tissues, including the gastrointestinal system. Korean ... -
Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage
Dil, Eyüp; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Yılmaz, Adnan; Samancı, Tuğba Çelik; Yazıcı, Zihni Açar (Verduci Publisher, 2023)OBJECTIVE: Approximately 70% of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of cancer, radiotherapy can also affect and damage surrounding healthy tissues in addition to ...
