Yazar "Serçinoğlu, Onur" için listeleme
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Computational investigation of peptide binding stabilities of HLA-B*27 and HLA-B*44 alleles
Bunsuz, Asuman; Serçinoğlu, Onur; Özbek, Pemra (Elsevier Ltd, 2020)Major Histocompatibility Complex (MHC) is a cell surface glycoprotein that binds to foreign antigens and presents them to T lymphocyte cells on the surface of Antigen Presenting Cells (APCs) for appropriate immune recognition. ... -
Identification of novel inhibitors of the ABC transporter BmrA
Serçinoğlu, Onur; Şentürk, Duygu; Altınışık Kaya, Fatma Ece; Avcı, Fatma Gizem; Frlan, Rok; Tomašič, Tihomir; Özbek, Pemra; Orelle, Cédric; Jault, Jean-Michel; Sarıyar Akbulut, Berna (Academic Press Inc., 2020)The resistance of microbes to commonly used antibiotics has become a worldwide health problem. A major underlying mechanism of microbial antibiotic resistance is the export of drugs from bacterial cells. Drug efflux is ... -
ProSNEx: a web-based application for exploration and analysis of protein structures using network formalism
Aydınkal, Rasim Murat; Serçinoğlu, Onur; Özbek, Pemra (Oxford Univ Press, 2019)ProSNEx (Protein Structure Network Explorer) is a web service for construction and analysis of Protein Structure Networks (PSNs) alongside amino acid flexibility, sequence conservation and annotation features. ProSNEx ... -
Sequence-structure-function relationships in class I MHC: A local frustration perspective
Serçinoğlu, Onur; Özbek, Pemra (Public Library Science, 2020)Class I Major Histocompatibility Complex (MHC) binds short antigenic peptides with the help of Peptide Loading Complex (PLC), and presents them to T-cell Receptors (TCRs) of cytotoxic T-cells and Killer-cell Immunglobulin-like ...
