Yazar "Serdaroğlu, Vildan" için listeleme
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Diastereoselective synthesis, characterization, investigation of anticancer, antibacterial activities, in silico approaches and DNA/BSA binding affinities of novel pyrimidine-sugar derivatives
Kahriman, Nuran; Serdaroğlu, Vildan; Aydın, Ali; Türkmenoğlu, Burçin; Usta, Asu (Elsevier, 2023)Eighteen novel carbohydrate conjugates (1-9) and their tetra-O-acetyl derivatives (10-18) were synthesized in total and evaluated for their biological properties, including antimicrobial and anticancer functions, and ... -
Molecular docking, synthesis and biological evaluation (enzyme inhibition, antimicrobial and antioxidant) of methoxy benzoin/benzil/stilbenoid derivatives
Yaylı, Nurettin; Kahriman, Nuran; Kılıç, Gözde; Serdaroğlu, Vildan; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Karaoğlu, Şengül Alpay; Yılmaz, Gizem Tatar (ACG Publications, 2022)In this study. methoxy benzoin compounds (1-10) were synthesized from the corresponding aromatic aldehydes based on a screening of biological activity. Oxidation and reduction of benzoins (1-10) yielded the corresponding ... -
New pyrimidine-N-β-D-glucosides: synthesis, biological evaluation, and molecular docking investigations
Kahriman, Nuran; Peker, Kıvanç; Serdaroğlu, Vildan; Aydın, Ali; Türkmenoğlu, Burçin; Usta, Asu; Yaylı, Nurettin (Scientific Technical Research Council Turkey, TÜBİTAK, 2023)In this study, syntheses of new pyrimidine-coupled N-beta-glucosides and tetra-O-acetyl derivatives were carried out. All glycoconjugates were investigated in comparison with known chemotherapeutic agents in terms of their ... -
Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA binding affinities
Kahriman, Nuran; Peker, Kıvanç; Serdaroğlu, Vildan; Aydın, Ali; Usta, Asu; Fandaklı, Seda; Yaylı, Nurettin (Academic Press Inc Elsevier Science, 2020)A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives were designed and synthesized by employing methyl substituted azachalcones. These novel compounds were evaluated and compared to the ... -
Synthesis and biological evaluation of new 2,4,6-trisubstituted pyrimidines and their N-alkyl derivatives
Kahriman, Nuran; Serdaroğlu, Vildan; Peker, Kıvanç; Aydın, Ali; Usta, Asu; Fandaklı, Seda; Yaylı, Nurettin (Academic Press Inc Elsevier Science, 2019)A series of new 2,4,6-trisubstituted pyrimidines and their N-alkyl bromide derivatives were prepared based upon methoxy substituted azachalcones as the starting materials. All newly synthesized compounds were screened for ... -
Synthesis of novel pyrazolines, their boron-fluorine complexes, and investigation of antibacterial, antioxidant, and enzyme inhibition activities
Kahriman, Nuran; Haşimoğlu, Zeynep; Serdaroğlu, Vildan; Beriş, Fatih Şaban; Barut, Burak; Yaylı, Nurettin (Wiley-V C H Verlag Gmbh, 2017)3,5-disubstituted-2-pyrazoline derivatives (4-6), their boron-fluorine complexes (boron (3-(2'-aminophenyl), 5-(2'-/3'-/4'-pyridyl) pyrazoline, BOAPPY) (7-9) and boron 1,2'-diazaflavone complex (BODAF) (11) were synthesized ...