Yazar "Tutar, Lütfi" için listeleme
-
HSP inhibitor sensitize resistant MCF-7 cells to doxorubicin through suppressing HSP90AB4P pseudogene and HSPB1 expression
Coşkun, Kübra Açıkalın; Tutar, Lütfi; Abay, Elif Cansu; Gülüm, Levent; Çelik, Ayşe Büşranur; Gümüş, Mehmet; Koca, İrfan; Tutar, Yusuf (Bentham Science Publishers, 2025)Introduction: Doxorubicin, a first-line chemotherapeutic agent, often faces resistance in breast cancer subtypes, leading to treatment failure. HSPs (Heat shock proteins), especially HSP90, and their pseudogenes like ... -
Metabolite-induced apoptosis by gundelia tournefortii in A549 lung cancer cells: A cytotoxic and gene expression study
Yüksel, Aysun; Celayir, Damla Nur; Tunoğlu, Ezgi Nurdan Yenilmez; Tutar, Lütfi; Tutar, Yusuf (MDPI, 2025)Background/Objectives: Gundelia tournefortii (Kenger) is a traditional medicinal plant and exhibits potential anticancer properties. This study investigates the cytotoxic and apoptotic effects of its water extract on human ... -
Non-genetic heterogeneity and immune subtyping in breast cancer: Implications for immunotherapy and targeted therapeutics
Hassan, Mudassir; Tutar, Lütfi; Sarı Ak, Duygu; Rasul, Azhar; Basheer, Ejaz; Tutar, Yusuf (Elsevier, 2024)Breast cancer (BC) is a complex and multifactorial disease, driven by genetic alterations that promote tumor growth and progression. However, recent research has highlighted the importance of non-genetic factors in shaping ...
