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Molecular docking, synthesis and biological evaluation (enzyme inhibition, antimicrobial and antioxidant) of methoxy benzoin/benzil/stilbenoid derivatives
Yaylı, Nurettin; Kahriman, Nuran; Kılıç, Gözde; Serdaroğlu, Vildan; Aliyazıcıoğlu, Rezzan; Sellitepe, Hasan Erdinç; Karaoğlu, Şengül Alpay; Yılmaz, Gizem Tatar (ACG Publications, 2022)In this study. methoxy benzoin compounds (1-10) were synthesized from the corresponding aromatic aldehydes based on a screening of biological activity. Oxidation and reduction of benzoins (1-10) yielded the corresponding ... -
Synthesis, biological evaluation and molecular docking studies of flavonol-3-O-β-D-glycoside as a potential inhibitor of SARS-CoV-2 main protease (3CLpro) in drug development for COVID-19
Çelik, Gonca; Karaoğlu, Şengül Alpay; Suyabatmaz, Şeyma; Bozdeveci, Arif; Yılmaz, Gizem Tatar; Yaylı, Nurettin; Akpınar, Rahşan; Çiçek, Ayşegül Çopur (Elsevier, 2025)The COVID-19 pandemic began in March 2020 and has affected many countries and infected over a million people. It has had a serious impact on people's physical and mental health, daily life and the global economy. Today, ...
