dc.contributor.author | Kılıç, Mustafa | |
dc.contributor.author | Kılıç, Betül | |
dc.contributor.author | Aydın, Mehmet Dumlu | |
dc.contributor.author | Kanat, Ayhan | |
dc.contributor.author | Yılmaz, İlhan | |
dc.contributor.author | Eseoğlu, Metehan | |
dc.contributor.author | Gündoğdu, Betül | |
dc.date.accessioned | 2020-12-19T19:40:27Z | |
dc.date.available | 2020-12-19T19:40:27Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Kilic, M., Kilic, B., Aydin, M. D., Kanat, A., Yilmaz, I., Eseoglu, M., & Gundogdu, B. (2019). Paradoxic Relations between Basilar Artery Reconfiguration and Superior Cervical Ganglia Ischemia After Bilateral Common Carotid Artery Ligation. World neurosurgery, 125, e658–e664. https://doi.org/10.1016/j.wneu.2019.01.144 | en_US |
dc.identifier.issn | 1878-8750 | |
dc.identifier.issn | 1878-8769 | |
dc.identifier.uri | https://doi.org/10.1016/j.wneu.2019.01.144 | |
dc.identifier.uri | https://hdl.handle.net/11436/1537 | |
dc.description | Kanat, Ayhan/0000-0002-8189-2877 | en_US |
dc.description | WOS: 000466491700082 | en_US |
dc.description | PubMed: 30716499 | en_US |
dc.description.abstract | BACKGROUND: the relationship between superior cervical ganglia (SCG) ischemia due to bilateral common carotid artery ligation (BCCAL) and basilar artery (BA) reconfiguration was investigated. METHODS: Twenty-three rabbits were randomly divided into 3 groups: group III rabbits underwent BCCAL (n = 13), group II rabbits were sham-operated controls (n = 5), and group I rabbits did not undergo surgery (n = 5). Degenerated neuron densities (DND) within the SCG were correlated with the BA vasodilatation index (VDI). RESULTS: Mean live and DND in SCG of group I rabbits were 11.235 +/- 982/mu m(3) and 11 +/- 3/mu m(3), respectively, with a mean heart rate of 294 +/- 21 beats/min. Mean SCG DND and heart rates were 213 +/- 42/mu m(3) and 242 +/- 17 beats/min for the sham group (group II) rabbits and 1743 +/- 285/mu m(3) and 199 +/- 19 beats/min for the study group (group III) rabbits, respectively. the BA VDI values in the sham group (group II) (1.32 +/- 0.10) and the study group (group III) (0.976 +/- 0.112) significantly differed from those in the control group (group I) (1.65 +/- 0.12; P < 0.005) versus the sham group (group II) (P < 0.0001) versus the BCCAL applied group (group III) and between group II and group III (P < 0.005). CONCLUSIONS: A meaningful and paradoxic correlation was detected between the BA VDI values and degenerated neuron density of SCG after BCCAL. Although a low degenerated neuron density within SCG may provoke excessive sympathetic activity and prevent excessive BA dilatation with steno-occlusive carotid artery diseases, a high degenerated neuron density may cause dangerous vasodilatation of BA. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier Science Inc | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Basilar artery vasodilatation | en_US |
dc.subject | Common carotid artery ligation | en_US |
dc.subject | Degenerated neuron density | en_US |
dc.subject | Superior cervical ganglion | en_US |
dc.title | Paradoxic relations between basilar artery reconfiguration and superior cervical ganglia ischemia after bilateral common carotid artery ligation | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Kanat, Ayhan | |
dc.identifier.doi | 10.1016/j.wneu.2019.01.144 | |
dc.identifier.volume | 125 | en_US |
dc.identifier.startpage | E658 | en_US |
dc.identifier.endpage | E664 | en_US |
dc.relation.journal | World Neurosurgery | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |