Synthesis and characterisation of some new hybrid molecules containing thiophene, triazole and coumarin rings under microwave conditions
Citation
Yılmaz, F. (2018). Synthesis and characterisation of some new hybrid molecules containing thiophene, triazole and coumarin rings under microwave conditions. Journal of Chemical Research, 7, 361-365. https://doi.org/10.3184/174751918X15314831778603Abstract
In this work, a new series of N'-{[4-amino-5-oxo-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-2-oxo-2H-1-benzopyran-3-carbohydrazides (thiophene-triazole-coumarin hybrid molecules) was synthesised from the reaction of 2-[4-amino-5-oxo-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetohydrazide and 3-(1H-benzotriazol-1-ylcarbonyl)-2H-chromen-2-ones by using microwave irradiation and conventional heating procedures and their results were compared. the reaction was performed using a very small amount of organic solvent and without using a catalyst.