dc.contributor.author | Polat, Hatice Beyazal | |
dc.contributor.author | Beyazal, Münevver Serdaroğlu | |
dc.date.accessioned | 2020-12-19T19:41:47Z | |
dc.date.available | 2020-12-19T19:41:47Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Polat, H. B., & Beyazal, M. S. (2018). The effect of cholecystectomy on 25-hydroxyvitamin D levels and bone mineral density in postmenopausal women. Archives of osteoporosis, 13(1), 61. https://doi.org/10.1007/s11657-018-0458-0 | en_US |
dc.identifier.issn | 1862-3522 | |
dc.identifier.issn | 1862-3514 | |
dc.identifier.uri | https://doi.org/10.1007/s11657-018-0458-0 | |
dc.identifier.uri | https://hdl.handle.net/11436/1829 | |
dc.description | Serdaroglu Beyazal, Munevver/0000-0001-5903-5708 | en_US |
dc.description | WOS: 000432875900002 | en_US |
dc.description | PubMed: 29790021 | en_US |
dc.description.abstract | Vitamin D deficiency has been reported in patients with gastrointestinal disorders. Little is known on the potentially deleterious effect of cholecystectomy on vitamin D levels and osteoporosis. We found that 25-hydroxyvitamin D levels and bone mineral density were lower in patients with prior cholecystectomy. Purpose the influence of bile salts on vitamin D absorption is well-known, and increased incidence of vitamin D deficiency has been reported in patients with gastrointestinal disorders. Little is known on the potentially deleterious effect of cholecystectomy on vitamin D levels and osteoporosis. Herein, we aimed to investigate the effects of cholecystectomy on vitamin D levels and osteoporosis in postmenopausal women. Methods the study group comprised 50 postmenopausal women who had previously undergone cholecystectomy; the control group comprised 50 age-matched postmenopausal women. Serum vitamin D, calcium, and phosphorus levels were determined. Bone mineral density (BMD) was determined using dual-energy X-ray absorptiometry. Results the study group had significantly higher parathyroid hormone levels (94.4 +/- 45.1 vs. 69.2 +/- 37.5, p < 0.001) but significantly lower 25-hydroxyvitamin D levels (16.3 +/- 7.6 vs. 19.8 +/- 8.7, p = 0.03). Compared with the control group, the BMDs of both the lumbar spine (-1.5 +/- 1.0 vs. -0.9 +/- 1.0, p = 0.004) and femur (-0.5 +/- 0.8 vs. 0.19 +/- 1.1, p = 0.001) were significantly lower in the study group. Body mass index [B = 0.81 (CI 0.67-0.98), p = 0.03] and prior cholecystectomy [B = 7.9 (CI 1.0-71.7), p = 0.04] were independent predictors of osteoporosis. Conclusion in postmenopausal women, prior cholecystectomy is associated with lower serum 25-hydroxyvitamin D levels and BMD. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Springer London Ltd | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Osteoporosis | en_US |
dc.subject | Cholecystectomy | en_US |
dc.subject | Vitamin D | en_US |
dc.subject | Postmenopausal women | en_US |
dc.title | The effect of cholecystectomy on 25-hydroxyvitamin D levels and bone mineral density in postmenopausal women | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Polat, Hatice Beyazal | |
dc.contributor.institutionauthor | Beyazal, Münevver Serdaroğlu | |
dc.identifier.doi | 10.1007/s11657-018-0458-0 | |
dc.identifier.volume | 13 | en_US |
dc.identifier.issue | 1 | en_US |
dc.relation.journal | Archives of Osteoporosis | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |