dc.contributor.author | Yılmaz, Fatih | |
dc.contributor.author | Menteşe, Emre | |
dc.contributor.author | Baltaş, Nimet | |
dc.date.accessioned | 2020-12-19T19:49:37Z | |
dc.date.available | 2020-12-19T19:49:37Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Yılmaz, F., Menteşe, E. & Baltaş, N. (2017). Synthesis and Antioxidant Evaluation of Some Novel Benzimidazole Derivatives Containing a Triazole Nucleus. Letters in Drug Design & Discovery, 14(2), 201-208. https://doi.org/10.2174/1570180813666160609082633 | en_US |
dc.identifier.issn | 1570-1808 | |
dc.identifier.issn | 1875-628X | |
dc.identifier.uri | https://doi.org/10.2174/1570180813666160609082633 | |
dc.identifier.uri | https://hdl.handle.net/11436/2311 | |
dc.description | WOS: 000395673500010 | en_US |
dc.description.abstract | Various benzimidazole compounds containing a triazole nucleus were synthesized and screened for their antioxidant activies. the structures of newly synthesized compounds were characterized by H-1 NMR, C-13 NMR and elemental analysis data. Antioxidant features of the synthesized compounds were investigated by different processes such as 2,2-diphenyl picryl hydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and CUPric reducing antioxidant capacity (CUPRAC) methods. Significant antioxidant activity was achieved by some of the synthesized compounds demonstrated as much activity as standards (AA and BHT). Correlation analysis between the CUPRAC antioxidant and ABTS radical scavenging assays revealed positive correlation (R-2=0.926), indicating differing antioxidant activities based on the reaction mechanism. | en_US |
dc.description.sponsorship | Recep Tayyip Erdogan University Scientific Research Project UnitRecep Tayyip Erdogan University [2014.102.02.05]; Recep Tayyip Erdogan UniversityRecep Tayyip Erdogan University | en_US |
dc.description.sponsorship | The authors report no conflicts of interest. This work was supported by Recep Tayyip Erdogan University Scientific Research Project Unit (BAP) under project number: 2014.102.02.05. Authors thank to Recep Tayyip Erdogan University for this support. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Bentham Science Publ Ltd | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 1 | en_US |
dc.subject | 2 | en_US |
dc.subject | 4-triazole | en_US |
dc.subject | Benzimidazole | en_US |
dc.subject | Antioxidant activity | en_US |
dc.subject | CUPRAC | en_US |
dc.subject | ABTS | en_US |
dc.subject | DPPH | en_US |
dc.title | Synthesis and antioxidant evaluation of some novel benzimidazole derivatives containing a triazole nucleus | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümü | en_US |
dc.contributor.institutionauthor | Yılmaz, Fatih | |
dc.contributor.institutionauthor | Menteşe, Emre | |
dc.contributor.institutionauthor | Baltaş, Nimet | |
dc.identifier.doi | 10.2174/1570180813666160609082633 | |
dc.identifier.volume | 14 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 201 | en_US |
dc.identifier.endpage | 208 | en_US |
dc.relation.journal | Letters in Drug Design & Discovery | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |