dc.contributor.author | Kahveci, Bahittin | |
dc.contributor.author | Yılmaz, Fatih | |
dc.contributor.author | Menteşe, Emre | |
dc.contributor.author | Ülker, Serdar | |
dc.date.accessioned | 2020-12-19T19:57:17Z | |
dc.date.available | 2020-12-19T19:57:17Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Kahveci, B., Yilmaz, F., Mentese, E., Ulker, E. (2015). Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities. Chemistry of Heterocyclic Compounds, 51(5), 447-456. https://doi.org/10.1007/s10593-015-1714-5 | en_US |
dc.identifier.issn | 0009-3122 | |
dc.identifier.issn | 1573-8353 | |
dc.identifier.uri | https://doi.org/10.1007/s10593-015-1714-5 | |
dc.identifier.uri | https://hdl.handle.net/11436/2834 | |
dc.description | WOS: 000358138200005 | en_US |
dc.description.abstract | By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly in terms of easy work-up and good yields. All newly synthesized compounds were screened for their antimicrobial activity and lipase inhibition. Most of the compounds were found to be effective on Escherichia coli. N'-{[4-Amino-3-(2-bromobenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-6-bromo-2-oxo-2Hchromene-3-carbohydrazide and N'-{[4-amino-3-(3,4-dichlorobenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-6-bromo-2-oxo-2H-chromene-3-carbohydrazide had a good effect on lipase inhibition. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Benzotriazole | en_US |
dc.subject | Coumarin | en_US |
dc.subject | 1,2,4-triazol-3-one | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Catalyst-free reaction | en_US |
dc.subject | Lipase inhibition | en_US |
dc.subject | Microwave irradiation | en_US |
dc.title | Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümü | en_US |
dc.contributor.institutionauthor | Yılmaz, Fatih | |
dc.contributor.institutionauthor | Menteşe, Emre | |
dc.contributor.institutionauthor | Ülker, Serdar | |
dc.identifier.doi | 10.1007/s10593-015-1714-5 | |
dc.identifier.volume | 51 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 447 | en_US |
dc.identifier.endpage | 456 | en_US |
dc.relation.journal | Chemistry of Heterocyclic Compounds | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |