dc.contributor.author | Menteşe, Emre | |
dc.contributor.author | Yılmaz, Fatih | |
dc.contributor.author | Beriş, Fatih Şaban | |
dc.contributor.author | Bekircan, Olcay | |
dc.contributor.author | Kahveci, Bahittin | |
dc.date.accessioned | 2020-12-19T19:58:51Z | |
dc.date.available | 2020-12-19T19:58:51Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Mentese, E., Yilmaz, F., Beris, F.S., Bekircan, O., Kahveci, B. (2015). Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity. Current Microwave Chemistry, 2(1), 32-39. https://doi.org/10.2174/221333560201150212104019 | en_US |
dc.identifier.issn | 2213-3356 | |
dc.identifier.issn | 2213-3364 | |
dc.identifier.uri | https://doi.org/10.2174/221333560201150212104019 | |
dc.identifier.uri | https://hdl.handle.net/11436/3011 | |
dc.description | WOS: 000218527700006 | en_US |
dc.description.abstract | 2-(2-Chlorobenzyl)-1H-benzimidazole (2) was prepared from the reaction of o-phenylenediamine and ethylimido-o-chlorophenylacetate hydrochloride (1) under microwave irradiation. the acetate and hydrazide derivatives of 2(2- chlorobenzyl)-1H-benzimidazole (2) were synthesized respectively. Then, 2-[2-(2-chlorobenzyl)-1H-benzimidazol-1yl]-N-(2,5-dioxopyrrolidin-1-yl) acetamide (5), 5-{[2-(2-chlorobenzyl)-1H-benzimidazol-1-yl]methyl}-1,3,4-oxadiazole2-thiol (6), acetohydrazide (7a-i) and N-phenylhydrazinecarbo thioamide derivatives (8a-c) were synthesized from hydrazide derivatives. Finally, the intramolecular cyclization of N-phenylhydrazinecarbo thioamide derivatives (8a-c) gave the corresponding 1,2,4-triazole-3-thione derivatives (9a-c). the newly synthesized compounds have been tested for their antimicrobial activity against three Gram-positive and three Gram-negative bacterias. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Bentham Science Publ Ltd | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 1,2,4-Triazole | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Benzimidazole | en_US |
dc.subject | Imine function | en_US |
dc.subject | Iminoester hydrochloride | en_US |
dc.subject | Microwave synthesis | en_US |
dc.subject | Oxadiazole | en_US |
dc.title | Microwave-assisted synthesis of some new benzimidazole derivatives with their antimicrobial activity | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Fen - Edebiyat Fakültesi, Kimya Bölümü | en_US |
dc.contributor.institutionauthor | Menteşe, Emre | |
dc.contributor.institutionauthor | Yılmaz, Fatih | |
dc.contributor.institutionauthor | Beriş, Fatih Şaban | |
dc.identifier.doi | 10.2174/221333560201150212104019 | |
dc.identifier.volume | 2 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 32 | en_US |
dc.identifier.endpage | 39 | en_US |
dc.relation.journal | Current Microwave Chemistry | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |