Microwave-assisted synthesis of some 1H-1,2,4-triazol-3-one derivatives
Citation
Karaali, N., Mentese, E., Yilmaz, F., Usta, A., Kahveci, B. (2013). Microwave-assisted synthesis of some 1H-1,2,4-triazol-3-one derivatives. South African Journal of Chemistry-Suid-Afrikaanse Tydskrif Vir Chemie, 66, 72-76.Abstract
4-Amino-5-(methyl/ethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one were synthesized from the reaction of (methyl/ethyl)-ester ethoxycarbonyl hydrazone with hydrazine hydrate and then, converted to corresponding Schiff bases using 9H-fluorene-3-carbaldehyde. Ester, hydrazide and oxadiazole derivatives were synthesized starting from Schiff bases in three steps. All reactions occurred under conventional conditions and microwave irradiation. the obtained results were compared.