Determination of protonation constants of some 3-alkyl(aryl)-4-(p-t- butyl(benzyl/benzyliden)amino)-4,5-dihydro-1h-1,2,4-triazole-5-one derivatives in ethanol-water mixtures

Abstract

Stoichiometric protonation constants of some 3-alkyl(aryl)-4-(p-t- butyl(benzyl/benzyliden)amino)-4,5-dihydro-1H-1,2,4-triazole-5-one derivatives were determined potentiometrically in 50% (v/v) ethanol-water mixtures at 25 °C with an ionic strength of 0.10 M. The calculation of the stoichiometric protonation constants was carried out using a PKAS computer program. The effect of solvents composition on the stoichiometric protonation constants are discussed. © 2010 Chemical Society of Ethiopia.