dc.contributor.author | Öksüz, Mustafa | |
dc.contributor.author | Yüce, Serdar | |
dc.contributor.author | Koçak, Ömer Faruk | |
dc.contributor.author | Canbaz, Yasin | |
dc.contributor.author | Rağbetli, Murat Çetin | |
dc.contributor.author | Mercantepe, Tolga | |
dc.date.accessioned | 2020-12-19T20:17:09Z | |
dc.date.available | 2020-12-19T20:17:09Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Öksüz, M., Yüce, S., Koçak, Ö. F., Canbaz, Y., Rağbetli, M. Ç., & Mercantepe, T. (2015). Effects of ozone pretreatment on viability of random pattern skin flaps in rats. Journal of plastic surgery and hand surgery, 49(5), 300–305. https://doi.org/10.3109/2000656X.2015.1047452 | en_US |
dc.identifier.issn | 2000-656X | |
dc.identifier.uri | https://doi.org/10.3109/2000656X.2015.1047452 | |
dc.identifier.uri | https://hdl.handle.net/11436/4343 | |
dc.description.abstract | Background: Medical ozone is a chemical agent that consists of three oxygen atoms and has antioxidant, angiogenic and vasodilator effects. This study evaluated the effects of medical ozone pre-treatment on flap survival. Materials and methods: Rats were divided into four groups of 10 rats each and a 9 × 3 cm McFarlane flap was used. Sham group: Neither surgical nor ozone pretreatment was used. Control group: No pretreatment was used after surgery. Preoperative ozone group: Preoperative 1 mg/kg ozone was given intraperitoneally for 7 days. No pretreatment was used after surgery. Postoperative ozone Group: Postoperative 1 mg/kg ozone was given intraperitoneally for 7 days. After postoperative 1 week, all groups were evaluated by surface area measurement, histopathology and electron microscopy. Results: With the experimental McFarlane flap model, the experimental groups had better surface area measurements, along with histopathological and electron microscopic results when compared with the control group. Conclusion: Medical ozone had positive effects on flap survival due to its antioxidant, angiogenic and vasodilator qualities. © 2015 Informa Healthcare. | en_US |
dc.description.sponsorship | Declaration of interest: This study was supported by the office of scientific research projects of Yüzüncü Yıl University. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor and Francis Ltd | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Flap necrosis | en_US |
dc.subject | McFarlane flap | en_US |
dc.subject | Ozone pre-treatment | en_US |
dc.title | Effects of ozone pretreatment on viability of random pattern skin flaps in rats | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Mercantepe, Tolga | |
dc.identifier.doi | 10.3109/2000656X.2015.1047452 | |
dc.identifier.volume | 49 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 300 | en_US |
dc.identifier.endpage | 305 | en_US |
dc.relation.journal | Journal of Plastic Surgery and Hand Surgery | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |