Green protocol: Catalyst-free synthesis of 2-substituted benzimidazoles under ultrasound irradiation

Abstract

The synthesis of 2-substituted benzimidazoles from the reaction of o-phenylenediamine and an imino ester hydrochloride with ultrasound irradiation is reported. The procedure has an eco-friendly and simple workup with good yield in a short time. © 2018 Science Reviews 2000 Ltd. All rights reserved.