Dislipidemide Ceviz veya Ceviz Suyunun Yeri

Abstract

Amaç: Bu çalışmada dislipidemi tedavisinde ceviz, ceviz suyu kürleri ve diyetin etkilerinin karşılaştırılması amaçlandı. Gereç ve Yöntem: Hastanemize başvuran, dislipidemisi olan 90 hasta araştırmamıza alındı. Rastgele 30’arlı üç grup oluş- turuldu. Alışılmış diyete ek olarak, birinci gruba her sabah 30 gram ceviz yemeleri, ikinci gruba her sabah 30 gr ceviz suyu içmeleri ve üçüncü gruba dislipidemi diyeti önerildi. Dört hafta sonra lipid parametreleri kontrol edildi. Bulgular: %55.6’sı kadın %44.4’ü erkek olan hastaların or- talama yaşı 49.1±13.3 idi. Ceviz kürü verilen grubun çalışma başında alınan ilk lipid düzeyleri sırasıyla total kolesterol: 246±39.8 mg/dl, LDL-k: 131.8±30.9 mg/dl, HDL: 44.3±14.7 mg/dl, TG: 147±99.1 olarak bulundu. Dört hafta sonra alınan kontrol düzeyleri; T-chol: 242±34.4 mg/dl, LDL-k: 134.7±28.2 mg/dl, HDL: 41.5±16.1 mg/dl, TG: 154±78.9 mg/dl idi. Arada- ki fark istatistiksel olarak anlamlı değildi (p>0.05). Ceviz suyu içen grubun ilk bakılan lipid düzeyleri; T-chol: 251.3±35.5 mg/dl, LDL-k: 129.9±32.3 mg/dl, HDL: 41.8±13.7 mg/dl, TG: 167±74.4 mg/dl olarak bulundu. Kontrol değerler; T-chol: 248±36.1 mg/dl, LDL: 125.3±31.9 mg/dl, HDL: 42.9±14 mg/ dl, TG: 174±68.7mg/dl olup aradaki fark istatistiksel olarak anlamlı değildi (p>0.05). Sadece diyet önerdiğimiz grubun ilk bakılan lipid düzeyleri; T-chol: 255.4±35.1mg/dl, LDL-k: 142.5±33.7 mg/dl, HDL: 43.8±17.3 mg/dl, TG: 158.8±79.6 mg/ dl olup, kontrol değerler; T-chol: 231.5±25.6 mg/dl, LDL-k: 119±28.1 mg/dl, HDL: 44.1±15.2 mg/dl, TG: 140.5±63.4 mg/dl olup aradaki fark istatistiksel olarak anlamlı bulundu (p<0.05). Sonuç: Cevizin dislipidemide tedavi amaçlı kullanımı yö- nünde bir sonuca varmak için daha geniş kapsamlı çalışma- lara ihtiyaç vardır. Dislipidemik hastalara diyetin önemini vurgulamanın halen en geçerli tedavi yöntemi olduğu düşüncesindeyiz.

Background: The aim of the present study was to evaluate the effects of walnut, walnut j uice, and diet on dyslipidemia. Methods: A total of 90 patients with dyslipidemia who applied to our hospital were included and randomly divided into 3 groups. In addition to routine diet, 30 grams of walnut were ad- ministered each morning to the 1st group, 30 grams of walnut j uice were administered to the 2nd group and a diet tailored for dyslipidemia was administered to the 3rd group. Lipid param- eters were checked after 4 weeks. Results: Mean age of patients, 55.6% of whom were female and 44.4% of whom were male, was 49. 1± 13.3 years. The first lipid levels of the first group were: total cholesterol (T-chol) 246±39.8 mg/dL, low-density lipoprotein (LDL) 13 1.8±30.9 mg/dL, high-density lipoprotein (HDL) 44.3± 14.7 mg/dL, and triglycerides (TG) 147±99. 1. After 4 weeks, control levels were: T-chol 242±34.4 mg/dL, LDL 134.7±28.2 mg/dL, HDL 4 1.5± 16. 1 mg/dL, and TG 154±78.9 mg/dL. Difference was not statisti- cally significant (p >0.05). Lipid levels of the 2nd group were: T- chol 25 1.3±35.5 mg/dL, LDL 129.9±32.3 mg/dL, HDL 4 1.8± 13.7 mg/dL, and TG 167±74.4 mg/dL. Control levels were T-chol 248±36. 1 mg/dL, LDL 125.3±3 1.9 mg/dL, HDL 42.9± 14 mg/dL, and TG 174±68.7 mg/dL. Difference was not statistically sig- nificant (p >0.05). Lipid levels of the group to which the diet was administered were: T-chol 255.4±35. 1 mg/dL, LDL 142.5±33.7 mg/dL, HDL 43.8± 17.3 mg/dL, and TG 158.8±79.6 mg/dL. Con- trol levels were: T-chol 23 1.5±25.6 mg/dL, LDL 119±28. 1 mg/ dL, HDL 44. 1± 15.2 mg/dL, and TG 140.5±63.4 mg/dL. Differ- ence was statistically significant (p >0.05). Conclusion: More ex tensive studies are needed to j udge the suitability of walnut in treating dyslipidemia. Results demon- strate that diet is still the best treatment.