dc.contributor.author | Durmuş, İsmet | |
dc.contributor.author | Kalaycıoğlu, Ezgi | |
dc.contributor.author | Çetin, Mustafa | |
dc.contributor.author | Şahin, Hanife Baykal | |
dc.date.accessioned | 2022-09-08T11:19:37Z | |
dc.date.available | 2022-09-08T11:19:37Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Durmuş, İ., Kalaycıoğlu, E., Çetin, M., Şahin, H. B., & Kırış, T. (2021). Exercise-Based Cardiac Rehabilitation Has a Strong Relationship with Mean Platelet Volume Reduction. Reabilitação Cardíaca Baseada em Exercícios Fortemente Relacionada com Redução do Volume Plaquetário Médio. Arquivos brasileiros de cardiologia, 116(3), 434–440. https://doi.org/10.36660/abc.20190514 | en_US |
dc.identifier.issn | 0066-782X | |
dc.identifier.uri | https://doi.org/10.36660/abc.20190514 | |
dc.identifier.uri | https://hdl.handle.net/11436/6416 | |
dc.description.abstract | Background: Mean platelet volume (MPV), which is a simple measure of platelet activation, has recently become an interesting topic in cardiovascular research. Exercise-based cardiac rehabilitation (CR) is a comprehensive intervention that decreases mortality-morbidity in patients with coronary artery disease (CAD). Studies on the effects of exercise on platelet activation have yielded conflicting results.
Objective: The purpose of this study was to determine the effect of an exercise-based CR programs on MPV in patients with stable CAD.
Methods: The sample was composed of 300 consecutive stable CAD patients. The patients were divided into two groups: CR group (n = 97) and non-CR group (n = 203). Blood analysis was performed. Point-Biserial correlation measures were performed to show correlation between MPV change and CR. A p value of <0.05 was considered statistically significant.
Results: The decrease in MPV was greater in the CR group than in the non-CR group [(-1.10(-1.40-(-0.90)) vs. (-0.10 (-2.00-0.00)); p< 0.001]. Delta MPV had a positive correlation with Delta neutrophil (r = 0.326, p < 0.001), Delta TG (r = 0.439, p < 0.001), Delta LDL-c (r = 0.478, p < 0.001), Delta WBC (r = 0.412, p < 0.001), and Delta CRP (r = 0.572, p < 0.001). A significant correlation was found between Delta MPV% and CR (r=0.750, p<0.001).
Conclusions: We were able to show that exercise-based CR has a strong relationship with MPV reduction in patients with CAD. We consider that decreased platelet activation with exercise-based CR might play an important role in reducing thrombotic risk in patients with stable CAD. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Arquıvos Brasileiros Cardiologia | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Cardiac, rehabilitation | en_US |
dc.subject | Exercise | en_US |
dc.subject | Physical, activity | en_US |
dc.subject | Mean platelet volume | en_US |
dc.subject | Blood platelets | en_US |
dc.subject | Coronary artery disease | en_US |
dc.subject | Echocardiography/methods | en_US |
dc.title | Exercise-based cardiac rehabilitation has a strong relationship with mean platelet volume reduction | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Çetin, Mustafa | |
dc.identifier.doi | 10.36660/abc.20190514 | en_US |
dc.identifier.volume | 116 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 434 | en_US |
dc.identifier.endpage | 440 | en_US |
dc.relation.journal | Arquivos Brasileiros de Cardiologia | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |