dc.contributor.author | Horsanali, Mustafa Ozan | |
dc.contributor.author | Eren, Hüseyin | |
dc.contributor.author | Dil, Eyüp | |
dc.contributor.author | Kazaz, İlke Onur | |
dc.contributor.author | Uzun, Hakkı | |
dc.date.accessioned | 2022-10-10T07:26:19Z | |
dc.date.available | 2022-10-10T07:26:19Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Horsanali, M. O., Eren, H., Dıl, E., Kazaz, I. O., & Uzun, H. (2021). A novel prognostic risk factor for patients undergoing radical prostatectomy: Triglyseride-glucose index. International journal of clinical practice, 75(5), e13978. https://doi.org/10.1111/ijcp.13978 | en_US |
dc.identifier.issn | 1368-5031 | |
dc.identifier.issn | 1742-1241 | |
dc.identifier.uri | https://doi.org/10.1111/ijcp.13978 | |
dc.identifier.uri | https://hdl.handle.net/11436/6687 | |
dc.description.abstract | Background: Obesity and metabolic syndrome are growing health problems in western countries. Recently reported triglyseride-glucose (TyG) index is a reliable and accessible indicator of metabolic syndrome. TyG index could be used as a indicator of a prognostic risk factor for metabolic syndrome-related cancers.
Objectives: To investigate the prognostic role of TyG index on oncological outcomes in patients undergoing radical prostatectomy.
Design, Setting and Participants: Data from 200 men who underwent radical prostatectomy were used.
Outcome Measurements and Statsitical Analyse: TyG was calculated based on TyG index = Ln [TG (mg/dL) FPG (mg/dL)/2] formula. Patients were divided into two groups according to the 8.55 level as cut-off value for TyG index. Laboratory results, oncological outcomes and survivals were comparised statistically between groups.
Results: Mean ages of patients were 64.32 +/- 6.1 years and median follow-up time was 61.6 +/- 35 (range 4-140) month. Biochemical recurrens was observed in 42 (21%) patients. Positive correlation between TyG index, body mass index, waist circumference, prostate biopsy gleason score, clinical T stage, positive surgical margin, pathological T stage and biochemical recurrence were observed. There was no statistical significance in terms of survival between groups.
Conclusion: Association between TyG index and prostate cancer may facilitate to predict unfavorable prognostic factors of radical prostatectomy. Increased TyG index may use as a predictive marker of positive surgical margin status before radical prostatectomy, BCR, advanced cT and pT stages after radical prostatectomy or worse biopsy gleason score in clinical practice. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | A novel prognostic risk factor for patients undergoing radical prostatectomy: Triglyseride-glucose index | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Eren, Hüseyin | |
dc.contributor.institutionauthor | Dil, Eyüp | |
dc.contributor.institutionauthor | Uzun, Hakkı | |
dc.identifier.doi | 10.1111/ijcp.13978 | en_US |
dc.identifier.volume | 75 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | e13978 | en_US |
dc.relation.journal | International Journal of Clinical Practice | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |