dc.contributor.author | Çetinkaya Altuntaş, Seher | |
dc.contributor.author | Avcı, Uğur | |
dc.date.accessioned | 2023-03-02T08:15:34Z | |
dc.date.available | 2023-03-02T08:15:34Z | |
dc.date.issued | 2022 | en_US |
dc.identifier.citation | Çetinkaya Altuntaş, S. & Avcı, U. (2022). Massive bilateral adrenal mass with adrenal insufficiency: a case report of primary adrenal lymphoma. The European Research Journal, 8(1), 126-130. https://doi.org/10.18621/eurj.821870 | en_US |
dc.identifier.issn | 2149-3189 | |
dc.identifier.uri | https://doi.org/10.18621/eurj.821870 | |
dc.identifier.uri | https://hdl.handle.net/11436/7755 | |
dc.description.abstract | Primary Adrenal Lymphoma (PAL) is extremely rare and usually occurs in men in the 6th-7th decade as bilateral,
diffuse large B-cell lymphoma (DLBCL). Here, an 80-year-old patient admitted to the urology outpatient clinic
with flank pain and bilateral adrenal mass detected on ultrasound is presented. Positron Emission TomographyComputed Tomography (PET-CT) was planned for the patient who was referred to the endocrine outpatient
clinic. The PET-CT scan revealed lobulated-contoured masses containing necrotic areas with a size of
7.4×5.5×9.8 cm, 19 Hounsfield Unit (HU), and SUVmax value of 23.9 the right adrenal, and with the size of
8.4×8.7×10.8 cm, 28 HU, SUVmax value of 27.3 in the left adrenal. These masses were reported to be not
compatible with metastasis and suggested a tumor of the adrenal origin or bilateral adrenocortical carcinoma.
In laboratory tests, since Adrenocorticotropic hormone level 291-592 pg/mL (high) and Cortisol level was 7.5-
9.5 mcg/dL (low), bilateral adrenalectomy was performed considering adrenocortical cancer primarily. Diffuse
large B cell lymphoma was determined as the result of the pathology. Postoperative hydrocortisone and
fludrocortisone treatment was initiated for the patient immediately. The patient was transferred to the
hematology inpatient clinic to receive Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and
Prednisolone chemotherapy. In this case report, we aimed to emphasize that the differential diagnosis should
be made well in massive bilateral adrenal masses. Although the diagnosis is challenging, clinicians should be
alert in diagnosing lymphoma in bilateral, massive adrenal masses with adrenal insufficiency. Since this
disease's prognosis is poor and aggressive, a histopathological diagnosis should be obtained, and treatment
should be initiated as soon as possible. | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Adrenal insufficiency | en_US |
dc.subject | non-Hodgkin's lymphoma | en_US |
dc.subject | Primary adrenal lymphoma | en_US |
dc.title | Massive bilateral adrenal mass with adrenal insufficiency: a case report of primary adrenal lymphoma | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Çetinkaya Altuntaş, Seher | |
dc.contributor.institutionauthor | Avcı, Uğur | |
dc.identifier.doi | 10.18621/eurj.821870 | en_US |
dc.identifier.volume | 8 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 126 | en_US |
dc.identifier.endpage | 130 | en_US |
dc.relation.journal | The European Research Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |