Kurum Yazarı "Mercantepe, Filiz" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
-
Circadian clock on ionizing radiation-induced testicular injury
Çiftel, Serpil; Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Çiftel, Enver (AVES, 2024)Objective: This research focuses on the interaction between the circadian clock and the damage caused to testicular tissue by x-ray ionizing radiation. By examining the links between circadian rhythms and radiation -induced ... -
Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats
Çiftel, Serpil; Mercantepe, Filiz; Mercantepe, Tolga; Çiftel, Enver; Klisic, Aleksandra (Springer, 2024)Scalding burns are a common form of thermal injury that often leads to systemic complications. Pro-inflammatory cytokines like interleukin-6 (IL-6) and the activation of signal transducer and activator of transcription 3 ... -
The effect of anti-tumor necrosis factor therapy on the plasma atherogenic index in rheumatic diseases
Cüre, Osman; Kızılkaya, Bayram; Çiftel, Serpil; Mercantepe, Filiz (Mary Ann Liebert Inc., 2024)Background: The risk of atherosclerosis is increased in individuals with rheumatological disease. The objective of this study is to examine the heightened susceptibility to atherosclerosis in persons afflicted with ... -
Effect of fibromyalgia on demographic, biochemical, metabolic and inflammatory profiles: a single-centre retrospective study
Cüre, Osman; Kızılkaya, Bayram; Çiftel, Serpil; Klisic, Aleksandra; Çiftel, Enver; Mercantepe, Filiz (Pisa, Italy : Pacini editore, 2024)Objectives: The objective of this study is to ascertain the disparities in demographic features and biochemical profiles between individuals diagnosed with fibromyalgia (FM) and a control group of healthy individuals. Methods: ... -
The effects of coenzyme Q10 (CoQ10) on Ionizing radiation- induced pancreatic β-cell injury
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz (AVES, 2023)Objective: This study investigated the antioxidant effect of coenzyme Q10 on ionizing radiation induced oxidative damage in pancreatic & beta;-cells. Methods: Twenty-four male rats were assigned to 4 groups. Group 1 ... -
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Akyıldız, Kerimali; Çiftel, Serpil; Yılmaz, Adnan (Karger, 2023)Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
Effects of gadolinium-based MRI contrast agents on liver tissue
Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Suzan, Zehra Topal; Çınar, Seda; Akyıldız, Kerimali; Mercantepe, Filiz; Yılmaz, Adnan (Wiley, 2018)BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ... -
Effects of infliximab against methotrexate toxicity in splenic tissue via the regulation of CD3, CD68, and C200R in rats
Mercantepe, Tolga; Tümkaya, Levent; Mercantepe, Filiz (Karger, 2018)Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ... -
The effects of N-acetylcysteine on radiotherapy-induced small intestinal damage in rats
Mercantepe, Filiz; Topçu, Atilla; Rakıcı, Sema; Tümkaya, Levent; Yılmaz, Adnan (Sage Publications Ltd, 2019)Six million cancer patients worldwide receive radiotherapy, either alone or in combination with other cancer treatments annually. the purpose of this study was to investigate, at the structural and molecular levels, the ... -
Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats
Eren, Hüseyin; Mercantepe, Tolga; Tümkaya, Levent; Mercantepe, Filiz; Dil, Eyüp; Horsanali, Mustafa Ozan; Yılmaz, Adnan (Academic Press Inc Elsevier Science, 2020)..... -
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
Çiftel, Serpil; Tümkaya, Levent; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Mercantepe, Tolga (Springer, 2024)Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ... -
Interleukins: Pathogenesis in non-alcoholic fatty liver disease
Rafaqat, Saira; Gluscevic, Sanja; Mercantepe, Filiz; Rafaqat, Sana; Klisic, Aleksandra (MDPI, 2024)Inflammatory cytokines have been implicated as crucial contributors to the onset and progression of non-alcoholic fatty liver disease (NAFLD). The exact mechanisms by which interleukins (ILs) contribute to NAFLD may vary, ... -
An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats
Topçu, Atilla; Mercantepe, Filiz; Rakıcı, Sema; Tümkaya, Levent; Uydu, Hüseyin Avni; Mercantepe, Tolga (Springer, 2019)According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ... -
The potential antioxidant effect of N-acetylcysteine on X-ray ionizing radiation-induced pancreas islet cell toxicity
Yılmaz, Hamit; Mercantepe, Tolga; Tümkaya, Levent; Merca; Yılmaz, Adnan; Rakıcı, Sema Yılmaz (Elsevier, 2023)Purpose Previous research has highlighted the impact of X-ray irradiation-induced organ damage, on cancer patients after radiation therapy. The ionizing radiation-induced oxidative stress causes injury to the pancreatic ... -
Prevalence of sensitization to airborne allergens among elderly population
Dursun, Adile Berna; Mercantepe, Filiz; Ayhan, Vehbi (Mosby-Elsevier, 2016)RATIONALE: Although the elderly population steadily increasing in all over the world, there is limited data on the prevalence of atopic sensitization in this population. The aim of the study is to investigate the prevalence ... -
Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury
Mercantepe, Filiz; Mercantepe, Tolga; Topçu, Atilla; Yılmaz, Adnan; Tümkaya, Levent (Springer, 2018)Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ... -
Protective effects of beta glucan in brain tissues of post-menopausal rats: a histochemical and ultra-structural study
Selli, Jale; Ünal, Deniz; Mercantepe, Filiz; Akaras, Nurhan; Kabayel, Rabia; Ünal, Bünyami; Atilay, Hilal (Taylor & Francis Ltd, 2016)Decline of estrogen during menopause has been associated with numerous significant changes that have been linked to many pathophysiological complications. in addition, ovarian hormone deficiency increases the production ... -
Protective effects of estrogen and bortezomib in kidney tissue of post-menopausal rats: an ultrastructural study
Mercantepe, Tolga; Ünal, Deniz; Selli, Jale; Mercantepe, Filiz; Ünal, Bünyamin; Karabıyık, Tuba Nur (Taylor & Francis Ltd, 2016)Purpose: Symptoms and disorders related to menopause and its associated estrogen deficiency have become a considerable health concern worldwide. Ovarian hormone depletion/estrogen deficiency can be usefully studied using ...