FEF, Kimya Bölümü Koleksiyonu: Recent submissions
Now showing items 141-160 of 481
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Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
(Wiley-V C Verlag GMBH, 2021)The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ... -
New potential monotherapeutic candidates for helicobacter pylori: Some pyridinazo compounds having both urease enzyme inhibition and anti-helicobacter pylori effectiveness
(Springer, 2021)To contribute to the monotherapeutic approach to Helicobacter pylori, some new pyridinazo compounds containing natural phenols such as eugenol and guaiacol were synthesized and their antioxidant capacities, urease enzyme ... -
Recent advances on smart glycoconjugate vaccines in infections and cancer
(Wiley, 2021)Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, ... -
Emerging glyco-based strategies to steer immune responses
(Wiley, 2021)Glycan structures are common posttranslational modifications of proteins, which serve multiple important structural roles (for instance in protein folding), but also are crucial participants in cell-cell communications and ... -
The cardioprotective mechanism of phenylaminoethyl selenides (PAESe) against doxorubicin-Induced cardiotoxicity involves frataxin
(Frontiers Media, 2021)Doxorubicin (DOX) is an anthracycline cancer chemotherapeutic that exhibits cumulative dose-limiting cardiotoxicity and limits its clinical utility. DOX treatment results in the development of morbid cardiac hypertrophy ... -
Toxic efficacy of Cuscuta campestris Yunck. (Solanales: Convolvulaceae) and Lupinus albus L. (Fabales: Fabaceae) plant crude extracts against nymphs and adults of Orosanga japonica (Melichar, 1898) (Hemiptera: Ricaniidae) under laboratory conditions
(Entomological Society of Turkey, 2021)The planthopper, Orosanga japonica (Melichar, 1898) (Hemiptera: Ricaniidae), is an important agricultural pest of grapevine, kiwifruit and tea in Asia and in some countries of Eastern Europe. The efficacy of the crude ... -
Properties of antioxidant and anti-inflammatory activity and phenolic profiles of şevketi bostan (cnicus benedictus l.) cultivated in aegean region from Turkey
(2017)The aim of this work was to evaluate the phenolic profiles and anti-inflammatory, antioxidant and gastro-protective activities of Cnicus benedictus L., a type of milk thistle cultivated in Turkey. The total phenolic content ... -
Non-enzymatic phenol determination in river water over modified electrode with poly(3-methylthiophene)
(2016)T his paper describes non-enzymatic phenol determination using poly(3methylthiophene) coated Pt electrode. Modified electrode was prepared on Pt disc surface in dichloromethane medium containing 500 mM 3-methylthiophene ... -
Water-soluble phthalocyanines containing azo dye; microwave-assisted synthesis and photochemical properties of ZnPcs
(Bilimsel Teknik Araştırma Konseyi Türkiye- TÜBİTAK, 2014)Novel water-soluble metallophthalocyanines (M: Co, Ni, Cu, Zn) containing azo dye were characterized. The structures were confirmed by IR, UV/vis, 1 H NMR, 13C NMR, mass spectroscopy, and elemental analysis. Photochemical ... -
Microwave-assisted synthesis and biological evaluation of some coumarin hydrazides
(2018)In this work, 15 different coumarin hydrazides were successfully synthesized and screened for their antioxidant and antilipase activities. To do this, firstly, salicylaldehyde derivatives and Meldrum's Acid were reacted ... -
Synthesis of some new benzimidazole derivatives containing chlorine and investigation of their antioxidant and anti-urease activities
(2018)In this work, the synthesis of a 2-substituted benzimidazole compound containing chlorine (1) was carried out and then converted to the ester (2) and hydrazide (3) derivatives respectively. In the next steps, the hydrazide ... -
Preparation of bentonite-cysteine (Bent-Cys) Micro-composite affinity sorbents for ferritin adsorption
(2007)his study focused on developing bentonite-cysteine micro-composite «affinity sorbents (Bent-Cys) (38-105 |am) for Ferritin adsorption from aqueous solutions. The pseudo-specific affinity ligand L-cysteine was immobilized ... -
Polianilin-poli(3-Metiltiyofen)-poli(3,3'- diaminobenzidin) elektrot üzerinden dopac tayini
(2015)Dopaminin önemli metaboliti olan 3,4-dihidroksifenilasetik asit (DOPAC) önemli bir biyolojik moleküldür [1]. Dopamin ile birlikte DOPAC; şizofreni [2], epilepsi [3], Parkinson [4], alzhemier [5] gibi nörolojik bozuklukların ... -
Bazı yeni potansiyel biyolojik 4-(Arylidenamino)-2, 4-dihidro-3H- 1,2,4-Triazol-3-one bileşiklerinin mikrodalga- destekli sentezi ve pKa değerlerinin belirlenmesi
(2016)Bu çalışmada,sekiz yeni bazı potansiyel biyolojik aktif 4-(arilidenamino)-2,4-dihidro-1H-1,2,4-triazol-3-on bileşikleri mikrodalga yöntemi kullanılarak sentezlendi. Bu bileşiklerin yapıları farklı spektroskopik yöntemle ... -
Isolation, production, and characterization of an extracellular lipase from Trichoderma harzianum isolated from soil
(2011)Bu çalışma, Trichoderma harzianum lipazının karakterizasyonu hakkında ilk rapordur. Yeni bir suş olan Trichoderma harzianum IDM14D topraktan izole edildi. İzole edilen bu suş, lipaz üretimi için çalkalamalı kültürde 30 ... -
Microwave-assisted synthesis of some benzimidazole derivatives containing imine function
(2015)Benzimidazol modern ilaç keşfinde önemli bir farmakofordur. Birçok benzimidazole türevi yeni ilaç adayı bileşikler elde etmek amacıyla organik kimyacılar tarafından sentezlenmektedir. Bu çalışmada, imin fonksiyonu içeren ... -
Evaluation of antioxidant activity of bee products of different bee races in Turkey
(2019)Bee products with high bioactive properties have a very important place in human nutrition. Biochemical properties of these products such as honey, pollen, and propolis vary according to flora, season, bee race, and ... -
Comparison of phenolic profiles and antioxidant activity of three Ornithogalum L. species
(2019)Background: Aboveground parts and bulbs of Ornithogalum species are consumed as food and used in traditional medicine in worldwide. Objective: It is aimed to report the antioxidant capacity and phenolic compounds content ... -
PaCaHa inhibits proliferation of human cancer cells in vitro
(2016)Background/aim: The aim of this study was to investigate the antiproliferative and cytotoxic effects of a newly synthesized molecule named paracetamol acetohydroxamic acid (PaCaHa) on human neoplastic cell lines. Materials ... -
Synthesis and characterization of polycarbazol - polyaniline copolymer in dichloromethane solution
(2015)Aromatik heterohalkalı organik molekülün yükseltgenmesi ile elektrot yüzeyinde veya çözeltide iletken polimerler sentezlenebilmektedir. Polipirol, politiyofen, polianilin, polifuran, polifenilenvinilen, politiyanaften, ...