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1,2,4-Triazole-conjugated fluoroquinolones as potential candidates for new antibacterial agents

dc.contributor.authorCebeci, Yıldız Uygun
dc.contributor.authorKaraoğlu, Şengül Alpay
dc.date.accessioned2024-06-24T07:13:03Z
dc.date.available2024-06-24T07:13:03Z
dc.date.issued2024en_US
dc.identifier.citationUygun Cebeci, Y., & Karaoglu, S. A. (2024). 1,2,4-Triazole-conjugated Fluoroquinolones as Potential Candidates for New Antibacterial Agents. Letters in Organic Chemistry, 21(8), 669-676. https://doi.org/10.2174/0115701786270260231215101046en_US
dc.identifier.issn1570-1786
dc.identifier.issn1875-6255
dc.identifier.urihttps://doi.org/10.2174/0115701786270260231215101046
dc.identifier.urihttps://hdl.handle.net/11436/9113
dc.description.abstractIn this study, synthesis of 1,2,4 triazole-fluoroquinolone hybrid compounds was realized. 7a-d hybrid compound was obtained as a result of mannich reaction with 6a-b triazole compounds norfloxacin and ciprofloxacin. 1H-NMR, 13C-NMR, Mass Spectrometry and Elemental Analysis confirmed the structures of all synthesized compounds. The antimicrobial activities of all compounds were investigated, and it was observed that 7a-d compounds, which are mannich bases, showed excellent activity.en_US
dc.language.isoengen_US
dc.publisherBentham Science Publicationsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFluoroquinolonesen_US
dc.subjectHybride moleculeen_US
dc.subjectTriazoleen_US
dc.subjectMannich baseen_US
dc.subjectSchiff baseen_US
dc.subjectAntibacterialen_US
dc.title1,2,4-Triazole-conjugated fluoroquinolones as potential candidates for new antibacterial agentsen_US
dc.typearticleen_US
dc.contributor.departmentRTEÜ, Fen - Edebiyat Fakültesi, Biyoloji Bölümüen_US
dc.contributor.institutionauthorKaraoğlu, Şengül Alpay
dc.identifier.doi10.2174/0115701786270260231215101046en_US
dc.identifier.volume21en_US
dc.identifier.issue8en_US
dc.identifier.startpage669en_US
dc.identifier.endpage676en_US
dc.relation.journalLetters in Organic Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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