Başlık için Biyomühendislik Bölümü Koleksiyonu listeleme
Toplam kayıt 42, listelenen: 14-33
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Development of all-solid-state antidiabetic drug metformin-selective microsensor and its electrochemical applications
(Wiley-V C H Verlag Gmbh, 2020)In this study, all-solid-state type potentiometric PVC membrane selective microsensor was developed for Metformin (MET) which is an antidiabetic drug active substance. Metformin-tetraphenylborate (MET-TPB) ion-pair was ... -
Development of MoS2 and Au nanoparticle including disposable CEA-based immuno-cytosensor platforms
(Springer, 2022)In this study, an electrochemical biosensor for determination of Carcinoembryonic antigen (CEA) biomarker using human breast ductal adenocarcinoma (MCF-7) and human ovarian adenocarcinoma (SK-OV-3) cancer cells was presented. ... -
Development of new cyclophilin d receptor inhibitors for the treatment of multiple sclerosis
(Ankara University, 2022)Objective: In this study, it was aimed to carry out computational studies for the development of new molecules for the inhibition of the cyclophilin D (CypD) receptor, which causes the disability of mitochondrial function ... -
Discovery of 5-(or 6)-benzoxazoles and oxazolo[4,5-b]pyridines as novel candidate antitumor agents targeting hTopo II alpha
(Elsevier, 2021)Discovery of novel anticancer drugs which have low toxicity and high activity is very significant area in anticancer drug research and development. One of the important targets for cancer treatment research is topoisomerase ... -
Drug repositioning approach for the treatment of ankylosing spondylitıs
(Ankara University, 2022)Objective: In this study, it was aimed to determine an FDA-approved molecule that inhibits the IL-17 receptor, which is an important target for the prevention of inflammation in Ankylosing Spondylitis (AS), using the ... -
Effects of extractive ammonia pretreatment on the ultrastructure and glycan composition of corn stover
(Frontiers Media Sa, 2019)Lignocellulosic biomass is highly recalcitrant and requires a pretreatment step to improve the enzyme accessibility and fermentable sugar yields during enzymatic hydrolysis. Our previous studies demonstrated the rearrangement ... -
Electrochemical evaluation of titanium (IV) oxide/polyacrylonitrile electrospun discharged battery coals as supercapacitor electrodes
(Wiley-V C H Verlag Gmbh, 2020)The TiO(2)nanoparticles are electrospun with polyacrylonitrile (PAN) polymer solution onto the discharged battery coal (DBC) electrode and the results are evaluated as a supercapacitor. the morphology and chemical composition ... -
An electrochemical immuno-cytosensor modified with nanofibers for the determination of a carcinoembryonic antigen
(Springer, 2024)In this study, La0.25Fe0.75FeO3 (PNp)perovskite nanoparticle was synthesized using the sol–gel method. PNp-coated polyacrylonitrile (PAN) nanofibers were prepared by electrospinning on the pencil graphite electrode (PGE) ... -
Electrochemical properties of coumarin 500 encapsulated in a liquid crystal guided electrospun fiber core and their supercapacitor application
(Amer Chemical Soc., 2022)Here, we first report a study on coumarin 500 and liquid crystal including polyacrylonitrile nanofibers in terms of synthesis, characterizations, and supercapacitor performances. SEM, POM, FTIR, and DSC measurements showed ... -
Evaluation of waste human hair as graphene oxide and examination of some characteristic properties
(TUBITAK, 2020)In this study, graphene oxide was synthesized from activated carbon obtained from waste hair for the first time using Modified Hummers method. the Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy ... -
Graphene-metallic nanocomposites as modifiers in electrochemical glucose biosensor transducers
(Iop Publishing Ltd, 2016)Graphene sheets and three different graphene-metallic nanocomposites including graphene-copper (graphene-Cu), graphene-nickel (graphene-Ni) and graphene-platinum (graphene-Pt) were prepared and characterized in the first ... -
Identification of novel inhibitors of the ABC transporter BmrA
(Academic Press Inc., 2020)The resistance of microbes to commonly used antibiotics has become a worldwide health problem. A major underlying mechanism of microbial antibiotic resistance is the export of drugs from bacterial cells. Drug efflux is ... -
In silico studies to develop new GSK3 beta inhibitors effective in the 's disease
(Bentham Science Publications, 2022)Background: Alzheimer's disease affects a large part of the world's population by prolonging the human life span and becoming an economic burden in the health system. Therefore, its treatment becomes more and more important ... -
In silico studies to develop new GSK3β inhibitors effective in the alzheimer's disease
(Bentham Science Publishers, 2022)Background: Alzheimer's disease affects a large part of the world’s population by prolonging the human life span and becoming an economic burden in the health system. Therefore, its treatment be-comes more and more important ... -
Mentha longifolia ssp. longifolia essential oil components as novel carbonic anhydrase isoform II and IX inhibitors: biological and molecular docking studies
(Bentham Science Publications, 2023)Background: Medicinal plant oils are used in the treatment of various human diseases due to their phytochemical components. Recently, enzyme inhibition studies have been increasing in cosmetics, the food industry, and ... -
Micro-Sized glucose biosensor based on composite pH sensor
(2018)Today's scientific and technical advances have led to significant advances in biosensor technology, leading to widespread use of biosensors in areas such as food technology, the environment, pharmaceuticals and clinical ... -
Molecular modeling strategies of cancer multidrug resistance
(Elsevier, 2021)Cancer remains a leading cause of morbidity and mortality worldwide. Hence, the increase in cancer cases observed in the elderly population, as well as in children and adolescents, makes human malignancies a prime target ... -
MoS2/Chitosan/GOx-Gelatin modified graphite surface: Preparation, characterization and its use for glucose determination
(Elsevier, 2021)Graphene-like new generation of two dimensional (2D) nanomaterials, in particular the family of transition metal dichalcogenides (TMDCs) have been attracting a wide range of research interest. Among the family of TMDCs, ... -
MS hastalığının tedavisine yönelik yeni Sfingosin-1-Fosfat reseptör modülatörlerinin geliştirilmesi
(Konya Teknik Üniversitesi, Mühendislik ve Doğa Bilimleri Fakültesi, 2022)Hesaplamalı ilaç tasarımı; ilaç geliştirme prosesini hızlandırmakla birlikte maliyeti de düşürerek tıp mühendisliğinin önde gelen alanlarından birine dönüşmüştür. MS hastalığı ölümle sonuçlanmasının yanı sıra, hastalarda ... -
Plant biomass: insights from imaging cell walls using molecular probes
(2016)Cell walls are an important and growing subject of research in plant biology. In the last decade, there has been an increasing interest in using cell walls as feedstock for the production of second generation biofuels. ...