Diagnostic value of serum thiobarbituric acid reactive substances levels in pediatric acute appendicitis

Abstract

Purpose: This study aims to show the diagnostic value of Serum Thiobarbituric Acid Reactive Substances in pediatric appendicitis. Method: Eighty-five pediatric patients hospitalized in the pediatric surgery ward with acute appendicitis and a control group of 50 pediatric patients with unspecific abdominal pain were included in this prospective case-control study. Forty-five patients whose pathology specimens confirmed acute appendicitis made up the final appendicitis group. Results: Patients with appendicitis had higher Serum Thiobarbituric Acid Reactive Substances (p<0.001) levels than the control group. In receiver operating characteristic analysis, areas under the curve were 0.654 for Serum Thiobarbituric Acid Reactive Substances. Conclusion: Serum Thiobarbituric Acid Reactive Substances test of patients with appendicitis provides limited accuracy in the diagnosis of appendicitis.