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Plasma homocysteine levels in dry eye patients

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Date

2013

Author

Şekeryapan, Berrak
Öner, Veysi
Kırbaş, Aynur
Türkyılmaz, Kemal
Durmuş, Mustafa

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Citation

Sekeryapan, B., Oner, V., Kirbas, A., Turkyilmaz, K., & Durmus, M. (2013). Plasma homocysteine levels in dry eye patients. Cornea, 32(5), e94–e96. https://doi.org/10.1097/ICO.0b013e31826f326b

Abstract

Purpose: To compare plasma homocysteine levels between patients with dry eye disease and normal control subjects. Methods: Plasma homocysteine (enzyme immunoassay), vitamin B12, and folate levels were determined in 38 patients with dry eye and in 38 controls. Results: Characteristics of the dry eye and control groups were similar. the mean plasma homocysteine level was 16.38 +/- 6.98 mmol/L in the dry eye group and 14.39 +/- 5.11 mu mol/L in the control group (P = 0.10, t test). Hyperhomocysteinemia was present in the 43.9% of the dry eye patients and 33.3% of the controls (P = 0.43, chi(2) test). There were no statistical differences between dry eye and control groups regarding plasma vitamin B12 and folate levels (P = 0.72 and P = 0.69, respectively, t test). Conclusions: Plasma homocysteine levels in dry eye patients may be inadequate to give homocysteine a role in pathogenesis. However, in ocular diseases like glaucoma, plasma homocysteine levels are significantly higher, and associated dry eye disease may cause an additional increase in plasma homocysteine levels.

Source

Cornea

Volume

32

Issue

5

URI

https://doi.org/10.1097/ICO.0b013e31826f326b
https://hdl.handle.net/11436/3344

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  • PubMed İndeksli Yayınlar Koleksiyonu [2443]
  • Scopus İndeksli Yayınlar Koleksiyonu [6032]
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  • TF, Temel Tıp Bilimleri Bölümü Koleksiyonu [700]
  • WoS İndeksli Yayınlar Koleksiyonu [5260]



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