Yazar "Kahveci, Bahittin" için listeleme
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Studies on the protonation constants of some triazoles in ethanol-water mixtures
İslamoğlu, Fatih; Kahveci, Bahittin; Özil, Musa; Akyüz, Emine (Chemical Publishing Co., 2008)Several studies, involving the formation and investigation of biological activities of some triazoles derivatives. These derivatives have weak acidic properties. To gain more information about the effect of solvent on ... -
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
Menteşe, Emre; Güner, Adem; Polatlı, Elifsu; Emirik, Mustafa; Bektaş, Hakan; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2020)The synthesis, docking study, and investigation of the anticancer activities of some coumarin derivatives containing the triazole ring are reported in this study. the newly synthesized compounds were screened for their in ... -
Synthesis and anticancer evaluation of some new 4-amino-3-(p-methoxybenzyl) -4,5-dihydro-1,2,4-triazole-5-one derivatives
Bekircan, Olcay; Küçük, Murat; Kahveci, Bahittin; Bektaş, Hakan (Verlag der Zeitschrift fur Naturforschung, 2008)4-Amino-3-p-methoxybenzyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl-acetic acid ethyl ester (2) was prepared from 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-one (1) and ethyl bromoacetate. Compound 3 was synthesized by the ... -
Synthesis and antimicrobial activity of some new triazole bridged benzimidazole substituted phthalonitrile and phthalocyanines
Kantar, Günay Kaya; Menteşe, Emre; Beriş, Fatih Şaban; Şaşmaz, Selami; Kahveci, Bahittin (Editura Acad Romane, 2018)In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole Newly synthesized ... -
Synthesis and antioxidant activities of some new triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings
Menteşe, Emre; Yılmaz, Fatih; Baltaş, Nimet; Bekircan, Olcay; Kahveci, Bahittin (Taylor & Francis Ltd, 2015)Various triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings (3-6) were synthesized and screened for their antioxidant activities. the structures of the synthesized compounds (2-6) were ... -
Synthesis and evaluation of alpha-glucosidase and pancreatic lipase inhibition by quinazolinone-coumarin hybrids
Menteşe, Emre; Karaali, Nesrin; Akyüz, Gülay; Yılmaz, Fatih; Ülker, Serdar; Kahveci, Bahittin (Springer, 2016)A new series of 2-substituted quinazolin-4(3H)-one derivatives including coumarin nucleus has been synthesized and screened for their lipase and a-glucosidase inhibition properties. Among the synthesized compounds, ... -
Synthesis and molecular docking study of some 5,6-dichloro-2cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease
Menteşe, Emre; Bektaş, Hakan; Sökmen, Bahar Bilgin; Emirik, Mustafa; Çakır, Demet; Kahveci, Bahittin (Pergamon-Elsevier Science Ltd, 2017)A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole ... -
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
Menteşe, Emre; Ülker, Serdar; Kahveci, Bahittin (Springer, 2015)A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ... -
Synthesis of 1,2,4-Triazole derivatives and determination of protonation constant
A microwave irradiation method has been developed for the synhesis of some 1,2,4-triazole derivatives using environmentally benign solvent ethanol in open vessels. Twelve 1,2,4-triazole derivatives were synthesized in good ... -
Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives
Kahveci, Bahittin (MDPI, ST ALBAN-ANLAGE 66, 2005)Iminoester hidroklorürler 1 sentezlenmiştir. Bu bileşikler daha sonra ester etoksikarbonil hidrazonlar 2'ye dönüştürüldü ve bunlardan sırasıyla yeni bir ikame edilmiş 4-amino-4,5-dihidro-lH-1,2,4-triazol-5-onlar, 3 serisi ... -
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
Özil, Musa; Khan, Khalid Mohammed; Baltaş, Nimet; Wadood, Abdul; Samad, Abdus; Kahveci, Bahittin (Elsevier, 2024)We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ... -
Synthesis of new coumarin containing benzimidazole derivatives
Menteşe, Emre; Yılmaz, Fatih; Mutlu, Fatih; Kahveci, Bahittin (Science Reviews 2000 Ltd, 2015)This study describes the synthesis of a new series of benzimidazoles that contain a coumarin moiety. the high yielding synthetic reaction was between hydrazide derivatives of benzimidazoles and 3-(1H-benzotriazol-1-ylcar ... -
Synthesis of new perimidine derivatives from the reaction of 1,8-diaminonapthalene with iminoester hydrochlorides
Kahveci, Bahittin; Karaali, Nesrin; Menteşe, Emre; Yılmaz, Fatih (Science Reviews 2000 Ltd, 2013)An alternative procedure is described for the synthesis of 2-substituted perimidines involving the reaction of 1,8-diaminonapthalene with iminoester hydrochlorides of substituted phenylacetic acids under microwave irradiation. ... -
Synthesis of novel 2,3-disubstituted quinazolin-4(3H)-one derivatives containing hydrazone skeleton as potent urease inhibitors and their antimicrobial activities
Akyüz, Gülay; Beriş, Fatih Şaban; Kahveci, Bahittin; Menteşe, Emre (Wiley, 2019)A new series of quinazolinones containing hydrazone moiety were synthesized, and their inhibitory activities on urease were assessed in vitro. Most of the compounds exhibited potent urease inhibitory activity. Among the ... -
Synthesis of novel triazol compounds containing isatin as potential antibacterial and antifungal agents by microwave and conventional methods
Özil, Musa; Menteşe, Emre; Yılmaz, Fatih; İslamoğlu, Fatih; Kahveci, Bahittin (Sage Publishing, 2011)Microwave irradiation has been used to accelerate the conversion of isatin (1a) and 5-nitroisatin (1b) into their Schiff bases 3-[5?-aryl(alkyl)- 2?,4?-dihydro-1?,2?,4?-triazol-3?-on- 4?-yl]iminoisatin (3a-g) and ... -
Synthesis of some N-alkoxycarbonyl-N"-benzoyl-benzamidrazones(p- toluamidrazones) and 1,3,5-trisubstituted 1,2,4-triazole derivatives from N-benzoylimidates and their antimicrobial and anticancer screening studies
Bekircan, Olcay; Kahveci, Bahittin; Özgümüş, Osman Birol (Wiley, 2007)Some new N-alkoxycarbonyl-N?-benzoyl-benzamidrazones (p-toluamidrazones) 3a-3d, and 1,3,5-trisubstituted 1,2,4-triazole 4a-4h derivatives by starting from N-benzoylbenzimidates or N-benzoyl-p-toluimidates. The structures ... -
Synthesis of some novel 1,2,4-triazol-3-one derivatives bearing the salicyl moiety and their anticonvulsant activities
Kahveci, Bahittin; Menteşe, Emre; Akkaya, Emre; Yılmaz, Fatih; Doğan, İnci Selin; Özel, Arzu (Wiley-V C H Verlag Gmbh, 2014)A series of new 1,2,4-triazole-3-one derivatives bearing the salicyl moiety were synthesized by using microwave irradiation, and their chemical structures were identified by IR, H-1 NMR, C-13 NMR, elemental analysis, and ... -
Synthesis of unsymmetrical 3,5-disubstituted 1,2,4-triazole derivatives with their pKa values
Bekircan, Olcay; İslamoğlu, Fatih; Menteşe, Emre; Kahveci, Bahittin (Chiminform Data S A, 2014)Acylhydrazones (2a-b) were synthesized by the condensation of iminoester hydrochlorides (1a-b) with benzhydrazide. the treatment of acylhydrazones With hydrazine hydrate afforded 4-amino-4H-1,2,4-triazoles. (3a-b). ... -
Synthesis, inhibitory properties on the metabolic enzymes and antioxidant activity of a new series benzimidazole derivatives
Karaali, Nesrin; Atik, Rıdvan; Balta, Nimet; Şaşmaz, Selami; Kahveci, Bahittin (Editura Acad Romane, 2019)In this study, a series of new 1, 2-disubstituted benzimidazole was synthesized starting from 5, 6-dichloro-2-(4-methoxybenzyl)-1H-benzimidazole compound which was converted to the ester and hydrazide derivative, respectively. ... -
Synthesis, molecular docking and biological evaluation of some benzimidazole derivatives as potent pancreatic lipase inhibitors
Menteşe, Emre; Yılmaz, Fatih; Emirik, Mustafa; Ülker, Serdar; Kahveci, Bahittin (Academic Press Inc Elsevier Science, 2018)In this study, a new series of benzimidazole and bisbenzimidazole derivatives were prepared via the reaction of iminoester hydrochlorides and o-phenylenediamines and then screened for their lipase inhibition properties. ...