Yazar "Arpa, Medeni" için listeleme
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Assessment of thiol/disulphide homeostasis in patients with knee osteoarthritis
Devrimsel, Gül; Arpa, Medeni; Beyazal, Münevver Serdaroğlu; Erel, Özcan (CSIR-National Institute of Science Communication and Policy Research (CSIR-NIScPR), 2021)Our aim was to explore the thiol/disulphide homeostasis and the link with functional status in patients who have knee OA. Sixty knee OA patients and 50 healthy individuals were enrolled in this study. We measured serum ... -
Association of serum interleukin-17 and Interleukin-23 levels with disease activity, function, mobility, enthesitis index in patients with ankylosing spondylitis
Beyazal, Münevver Serdaroğlu; Tayfun, Aliekber; Devrimsel, Gül; Yıldırım, Murat; Arpa, Medeni (Georg Thieme Verlag, 2022)Aim: More and more studies have demonstrated that the interleukin (IL)-23/IL-17 axis is highly associated with immune dysfunction and activated autoimmune inflammation. The purposes of this study were to determine the serum ... -
A comparison study of dual-energy spectral CT and 18F-FDG PET/CT in primary tumors and lymph nodes of lung cancer
Kupik, Osman; Metin, Yavuz; Eren, Gülnihan; Metin, Nurgül Orhan; Arpa, Medeni (Turkish Society of Radiology, 2021)PURPOSE We aimed to investigate whether there is a correlation between dual-energy spectral computed tomography (DESCT) and 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) parameters ... -
Development of hepatocellular carcinoma in patients with chronic hepatitis C who had sustained viral response following direct-acting antiviral therapy
Ebik, Berat; Aygan, Mustafa; Tuncel, Elif Tuğba; Kaçmaz, Hüseyin; Ekin, Nazım; Arpa, Medeni; Yalçın, Kendal (Kare Publishing, 2022)Background and Aim: Several studies have suggested that treatment with direct-acting antivirals (DAAs) in patients with chronic hepatitis C virus (HCV) may be associated with an increased risk of developing hepatocellular ... -
Did diet compliance and remission reduce oxidative stress in celiac patients?
Ebik, Berat; Bacaksız, Emin; Uzel, Ali; Akkuzu, Mustafa Zanyar; Yavuz, Ahmet; Kaçmaz, Hüseyin; Aslan, Nihat; Arpa, Medeni; Neşelioğlu, Salim; Erel, Özcan (Associacao Medica Brasileira, 2024)OBJECTIVE: We aimed to examine the effect of remission status on thiol–disulfide homeostasis in celiac patients and thus to indirectly determine the effect of oxidative stress and inflammation caused by non-compliance with ... -
Do volume-based and metabolic 18F FDG PET/CT parameters identify groups at risk for poor prognosis in patients with newly diagnosed metastatic and non-metastatic non-small cell lung cancer?
Kupik, Osman; Bozkurt, Mehmet; Asa, Sertaç; Eren, Gülnihan; Gündoğdu, Hasan; Arpa, Medeni (Akad Doktorlar Yayinevi, 2020)To determine the relationship between F-18 FDG PET/CT parameters of the primary tumor/nodal metastasis/distant metastasis and overall survival (OS) of patients with newly diagnosed non-small cell lung cancer (NSCLC). Data ... -
Dynamic thiol/disulphide balance in patients undergoing hypotensive anesthesia in elective septoplasties
Kazancıoğlu, Leyla; Batçık, Şule; Arpa, Medeni; Erdivanlı, Başar; Özergin Coşkun, Zerrin; Erdivanlı, Özlem Çelebi; Bahçeci, İlkay; Kazdal, Hızır; Erel, Özcan; Neşelioğlu, Salim (Wiley-Hindawi, 2021)Objective We aimed to investigate the effects of hypotensive anaesthesia on oxidative stress with serum thiol/disulphide balance in patients undergoing elective septoplasty procedures under general anaesthesia. Methods ... -
The effect of high serum lipid level on benign gallbladder diseases
Uyan, Mikail; Şen, Bayram; Arpa, Medeni; Okçu, Oğuzhan (Effect Publishing Agency ( EPA ), 2022)There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
Topçu, Atilla; Öztürk, Aykut; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
Deniz, Esra; Topçu, Atilla; Öztürk, Aykut; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
Evaluating serum elastin levels in striae gravidarum
Gürlek, Beril; Ural, Ülkü Mete; Tuğcugil, Sibel; Arpa, Medeni; Önal, Özgür (Walter de Gruyter Gmbh, 2020)Objective: Striae gravidarum (SG) is the most common dermatological defect in pregnancy leading to cosmetic anxiety with unknown etiopathogenesis. the aim of the study was to analyze the relation between serum elastin ... -
Evaluation of choroidal thickness and retinal vessel density with serum HIF-1α and TNF-α level in patients with OSAS
Sağır, Büşra; Okutucu, Murat; Arpa, Medeni; Fındık, Hüseyin; Uzun, Feyzahan; Aslan, Mehmet Gökhan; Şahin, Ünal; Kaim, Muahmmet (Taylor & Francis Ltd., 2024)Purpose: To reveal changes in choroidal thickness, retinal vessel density, and serum HIF-1α and TNF-α levels in obstructive sleep apnea syndrome (OSAS) and their correlation. Methods: This prospective case-control study ... -
Evaluation of periostin, fibronectin and tenascin-C in patients chronic otitis media with cholesteatoma
Birinci, Mehmet; Terzi, Suat; Demir, Emine; Çeliker, Metin; Okcu, Oğuzhan; Arpa, Medeni; Çelebi, Özlem; Özergin, Zerrin; Dursun, Engin (Springer, 2022)Background: Although many studies have investigated the mechanisms of cholesteatoma formation, its pathogenesis remains unclear. The aim of this study was to evaluate the levels of periostin, fibronectin and tenascin-C, ... -
Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome
Okutucu, Murat; Arpa, Medeni (Springer, 2023)Purpose: To evaluate serum semaphorin 3A (Sema3A) and interleukin 6 (IL-6) levels in pseudoexfoliation syndrome (PXS) patients to determine whether these mediators play a role in the systemic manifestations of PXS. Methods: ... -
Evaluation of thiol-disulfide homeostasis in active ankylosing spondylitis patients
Arpa, Medeni; Şen, Bayram; Beyazal, Münevver Serdaroğlu; Erel, Özcan (Ediciones Doyma, S.L., 2021)Introduction and objectives: The etiopathogenesis of ankylosing spondylitis (AS), which is a chronic, progressive, inflammatory, systemic disease, has not been fully elucidated yet. Thiol-disulfide homeostasis, a component ... -
Evaluation of thiol/disulfide homeostasis in bronchiectasis
Özyurt, Songül; Özçelik, Neslihan; Kara, Bilge Yılmaz; Arpa, Medeni; Metin, Yavuz; Erel, Özcan; Neşelioğlu, Salim (Hindawi, 2022)Purpose. Thiols are sulfhydryl-containing organic compounds that have an important role in preventing cellular oxidative stress. This study compares the blood oxidative stress marker levels in bronchiectasis cases during ... -
Factors affecting mortality in COVID-19 patients treated with tocilizumab
Cüre, Osman; İlkkılıç, Kadir; Şen, Bayram; Arpa, Medeni; Aydın, Esra; Avcı, Uğur; Tüfekçi, Damla; Polat, Hatice Beyazal; Kızılkaya, Bayram (Yuzuncu Yil Universitesi Tip Fakultesi, 2024)The aim of our study was to evaluate the risk factors associated with mortality in COVID-19 patients. During March 2020 to March 2022, 136 patients who were treated with tocilizumab in the service and intensive care unit ... -
FOBTs with lower detection limits increase the colonoscopy rates
Şen, Bayram; Okcu, Oğuzhan; Arpa, Medeni; Akdoğan, Remzi Adnan (Türk Klinik Biyokimya Derneği, 2023)Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, ...