Yazar "Emirik, Mustafa" için listeleme
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Acetate bridged dinuclear Cu(II) complexes with ferrocene based benzimidazol ligands: Synthesis, spectroscopy, electrochemistry, DFT calculations and catecholase activity
Karaoğlu, Kaan; Emirik, Mustafa; Menteşe, Emre; Zengin, Ali; Serbest, Kerim (Pergamon-Elsevier Science Ltd, 2016)Two new benzimidazole ligands, 1-[(E)-ferrocenylmethylidenehydrazino]-2-{5,6-dichloro-2-[(o-chloro-phenyl)methyl]-1,3-diaza-1H-inden-1-yl}-1-ethanone (1) and 1-[(E)-ferrocenylmethylidenehydrazino]-2-{2-[p-(trifluoromethy ... -
Adsorption of Reactive Red 120 from aqueous solutions by cetylpyridinium-bentonite
Tabak, Ahmet; Baltaş, Nimet; Afşin, Beytullah; Emirik, Mustafa; Çağlar, Bülent; Eren, Erdal (Wiley, 2010)BACKGROUND: The removal of Reactive Red 120 (RR 120) from aqueous solutions using cetylpyridinium modified Resadiye bentonite (CP-bentonite) prepared by ion exchange was investigated with particular reference to the effects ... -
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
Güven, Okan; Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin; Akyüz, Gülay (Wiley, 2023)This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ... -
Binuclear Cu(II), Ni(II) and Zn(II) complexes of hydrazone Schiff bases: Synthesis, spectroscopy, DFT calculations, and SOD mimetic activity
Zengin, Ali; Serbest, Kerim; Emirik, Mustafa; Özil, Musa; Menteşe, Emre; Faiz, Özlem (Elsevier, 2023)Two new salicylaldimine-based N-heterocyclic hydrazone ligands, N'-[(2-hydroxyphenyl) methylene]2-(2-phenyl-1H-benzimidazol-1-yl)acetohydrazone (H 2 L 1 ) and 2-[2-(3-chlorobenzyl)-1H-benzimidazol-1yl]-N'-[(2-(hydroxyimi ... -
Chalcone-based dipolar cycloaddition of novel heteroaromatic compounds: Their anticancer examination
Kınalı, Mehmet; Çöl, Sümeyye; Çoban, Canan Çakır; Türk, Mustafa; Aydın, Gökay; Emirik, Mustafa; Baran, Arif (Elsevier, 2023)In this study, new chalcone-isoxazole-based hybrid derivatives (12, 13, 18, and 21) and chalcone-triazole hybrid molecules (26) were synthesized using the click chemistry approach. Among these hybrid molecules, 12, 13, 21, ... -
Comparison of electrostatic potential obtained from different atomic point charges calculation methods for a large set of molecules
Emirik, Mustafa; Yılmaz, Sevil Savaşkan (World Stientific Publishing, 2021)The Electrostatic Potential is of great importance in chemical reactivity since it is closely related to many of molecular properties. Despite the fact that there are significant improvements in the quantum mechanical ... -
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
Menteşe, Emre; Emirik, Mustafa; Sökmen, Bahar Bilgin (Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
Özil, Musa; Tuzcuoğlu, Özge; Emirik, Mustafa; Baltaş, Nimet (Wiley-V C Verlag GMBH, 2021)The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ... -
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
Menteşe, Emre; Yılmaz, Fatih; Menteşe, Meltem; Beriş, Fatih Şaban; Emirik, Mustafa (Wiley, 2024)In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ... -
Ferrocenyl-substituted dinuclear Cu(II) complex: Synthesis, spectroscopy, electrochemistry, DFT calculations and catecholase activity
Emirik, Mustafa; Karaoğlu, Kaan; Serbest, Kerim; Menteşe, Emre; Yılmaz, İsmail (Elsevier Science Bv, 2016)A new ferrocenyl-substituted heterocyclic hydrazide ligand and its Cu(II) complex were prepared. the DFT calculations were performed to determine the electronic and molecular structures of the title compounds. the electronic ... -
Heteroligand bivalent transition metal complexes with an azo-oxime ligand and 1,10-phenanthroline: Synthesis, spectroscopy, thermal analysis, DFT calculations and SOD-mimetic activities
Serbest, Kerim; Dural, Turan; Emirik, Mustafa; Zengin, Ali; Faiz, Özlem (Elsevier B.V., 2021)Novel mononuclear heteroligand transition metal complexes: [M(HL)(phen)2]ClO4, (M: Mn(II) for 1, Ni(II) for 2), [M(HL)(phen)(ClO4)], (Ni(II) for 3, Cu(II) for 4, Zn(II) for 5) with 2-[(E)-(hydroxyimino)methyl]-4-[(E)-phe ... -
In silico inhibition potential of artemisinin derivatives against SARS-CoV-2 main protease
Emirik, Mustafa (TUBİTAK Scientific & Technical Research Council Turkey, 2021)The outbreak of COVID-19 caused by the SARS-CoV-2 virus has recently affected millions worldwide. The natural compounds obtained from medicinal plants have been proven to be the source of many treatments throughout history. ... -
Iron(III) complexes derived from azo-containing salicylaldoxime ligands: Synthesis, structures and biological evaluations
Serbest, Kerim; Dural, Bayram; Çöl Ayaz, Melek; Zengin, Ali; Emirik, Mustafa (TUBİTAK Scientific & Technical Research Council Turkey, 2021)Two novel mononuclear Fe(III) complexes derived from azo-containing salicylaldoxime ligands were synthesized and characterized by elemental analyses, spectroscopic data i.e. IR, 1H NMR, UV-Vis, electrospray ionization mass ... -
Metabolite profiling of Althaea officinalis by HPLC-DAD-MS with in silico and in vitro analysis for therapeutic potential
Turumtay, Emine Akyüz; Demir, Adem; Çetiz, Mehmet Veysi; Uudağ, Emre Berk; Baltaş, Nimet; Yaman, Burak; Yaman, Mehmet; Emirik, Mustafa; Turumtay, Halbay (Springer, 2023)Althaea officinalis L. has been widely used traditionally as an herbal tea and for the treatment of cough, mucous membrane irritation, colds, and inflammation. Parts of the plant extracts were analyzed using HPLC-DAD and ... -
Metal catalyst-free β-amination of branched rac-C8N-type such as C7N carbasugars via intramolecular aza-michael addition: Biological evolution, DFT studies and ADME properties
Baran, Arif; Savran, Tahir; Aydın, Gökay; Emirik, Mustafa (Elsevier, 2025)In this study, a new stereospecific strategy for the preparation of C8N aminocyclohexenols such as C7N, validamine analogs were developed from starting compound 4 via intramolecular aza-michael β-amination reaction between ... -
Molecular docking studies and synthesis of novel bisbenzimidazole derivatives as inhibitors of alpha-glucosidase
Özil, Musa; Emirik, Mustafa; Beldüz, Ali; Ülker, Serdar (Pergamon-Elsevier Science Ltd, 2016)A series of bisbenzimidazole derivatives starting from o-phenylenediamine and 4-nitro-o-phenylenediamine were prepared with oxalic acid. Most of the reactions were conducted using both the microwave and conventional methods ... -
Mononuclear Cu(II) complex of an oxime ligand derived from N-Heterocyclic hydrazide: Synthesis, spectroscopy, electrochemistry, DFT calculations and catecholase activity
Zengin, Ali; Karaoğlu, Kaan; Emirik, Mustafa; Menteşe, Emre; Serbest, Kerim (Elsevier Science Bv, 2019)A new oxime derivative N-heterocyclic hydrazide ligand, N'-[(1E,2E)-2-(hydroxyimino)-1-methylpropylidene]-2-[(4-methyl-5-phenyl-4H-1,2,4-triazol-3-1)thio] acetohydrazide (1) and its mono-nuclear copper(II) complex (1a) ... -
New 1,3,4-thiadiazol derivatives: Synthesis, computational study and X-Ray
Ünlüer, Dilek; Düğdü, Esra; Emirik, Mustafa; ŞAhin, Onur; Ünver, Yasemin; Sancak, Kemal (Elsevier, 2020)In this study, 4-hydroxyphenyl-3H-1,2,4-triazol-3-one derivatives (la-d), cyanomethoxyphenyl-3-alkyl/aryl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-acetonitriles (2a-d) and bis amino-1,3,4-thiadiazol-5-alkyl/aryl-2,4-dihydro-3H ... -
New chalcone derivatives with Schiff base-thiophene: Synthesis, biological activity, and molecular docking studies
Ünver, Yasemin; Tuluk, M.; Kahriman, Nuran; Emirik, Mustafa; Bektaş, Ersan; Direkel, Şahin (Maik Nauka/Interperiodica/Springer, 2019)New thiophene chalcones 3, 6 and thiophene Schiff base-chalcone derivatives 4a-4d, 7a-7d are synthesized. Structures of the compounds are confirmed by H-1 and C-13 NMR, and IR spectra. According to antimicrobial and ... -
A novel ferrocenyl naphthoquinone fused crown ether as a multisensor for water determination in acetonitrile and selective cation binding
Dağdevren, Metin; Yılmaz, İsmail; Yücel, Barış; Emirik, Mustafa (Amer Chemical Soc, 2015)A multisensor which is based on a novel multifunctional triad molecule, ferrocenyl naphthoquinone fused crown ether (Fc-cnq) bearing ferrocene, quinone, and crown ether functional groups together, was synthesized and ...
