• The prognostic impact of Her2 status in early triple negative breast cancer: a Turkish Oncology Group (TOG) study 

  Özyurt, Neslihan; Alkan, Ali; Gülbağcı, Burcu; Seyyar, Mustafa; Aydın, Esra; Şahbazlar, Mustafa; Türker, Mehmet; Kınıkoğlu, Oğuzcan; Yerlikaya, Tahir; Dinç, Gülhan; Aytaç, Ali; Kalkan, Ziya; Ebinç, Senar; Gültürk, İlkay; Keskinkılıç, Merve; İşleyen, Zehra Sucuoğlu; Çağlayan, Dilek; Türkel, Alper; Şakalar, Teoman; Sekmek, Serhat; Yıldırım, Nilgün; Koçak, Sinem; Okutur, Kerem; Özveren, Ahmet; Dursun, Bengü; Kitaplı, Sait; Eren, Orhan Önder; Beypınar, İsmail; Hacıbekiroğlu, İlhan; Çabuk, Devrim; Karaman, Elanur; Acar, Ömer; Paydaş, Semra; Eryılmaz, Melek Karakurt; Demir, Bilgin; Oruç, Zeynep; Yılmaz, Mesut; Biricik, Fatih Selçuk; Salim, Derya Kıvrak; Tanrıverdi, Özgür; Doğan, Mutlu (Nature Research, 2024)

  The studies evaluating the impact of Her2 levels in neoadjuvant setting have conflicting data. The aim of the study was to evaluate the prognostic impact of Her2 status in early triple negative breast cancer(TNBC). In the ...

• Knowledge about metabolic dysfunction-associated steatotic liver disease among the medical professionals from countries in the MENA region 

  Alqahtani, Saleh A.; Yılmaz, Yusuf; El-Kassas, Mohamed; Alswat, Khalid; Mawardi, Mohamed; Sanai, Faisal M.; Abaakhail, Faisal; Alghamdi, Saad; Al-Hamoudi, Waleed K; Nader, Fatema; Younossi, Zobair M. (Elsevier, 2024)

  Introduction and Objectives: Given the substantial burden of metabolic dysfunction-associated steatotic liver disease (MASLD), there is an urgent need to assess knowledge and awareness levels among physicians. We assessed ...

• Comparison of the effectiveness of thymoquinone, St. John Wort oil and silver sulfadiazine in experimental burn wounds 

  Canbaz, Yasin; Karakol, Perçin; Erten, Remzi; Mercantepe, Tolga; Alp, Hamit Hakan; Canbaz, Esra Turan; Turel, İdris; Rağbetli, Murat Çetin; Yüce, Serdar (Oxford University Press, 2024)

  We aimed to compare the effectiveness of thymoquinone (TQ), the most important bioactive component of black cumin, St. John wort (SJW) oil, a traditional medicinal plant used in burns, and silver sulfadiazine (AgSD), a ...

• The impact of HER2-low status on pathological complete response and disease-free survival in early-stage breast cancer 

  Şen, Gülin Alkan; Aydın, Esra; Guliyev, Murad; Öztaş, Nihan Şentürk; Değerli, Ezgi; Demirci, Nebi Serkan; Turna, Zeynep Hande; Demirelli, Fuat Hulisi (BMC, 2024)

  BackgroundThe HER-2 status of breast cancer (BC) has been classified as negative or positive for a long time. Given the efficacy of novel anti-HER2-targeted antibody drug conjugates (ADCs) in HER2-low BC, a distinct subgroup ...

• Uric acid to albumin ratio as a predictive marker for intracoronary thrombus severity in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) 

  Duman, Hakan; İpek, Emrah; Durak, Hüseyin; Şahin, Müjgan Ayşenur; Ergül, Elif; Yılmaz, Ahmet Seyda; Bakırcı, Eftal Murat (Int Scientific Information, 2024)

  Background: This study assessed the association between a novel inflammatory marker, uric acid (UA)-to-albumin ratio (UAR), and preprocedural intracoronary artery thrombus (ICAT) in ST elevation myocardial infarction ...

• Spleen stiffness measurement improves non-invasive prediction of clinically significant portal hypertension in primary biliary cholangitis 

  Manfredi, G. F.; Ergenç, İ.; Cittone, M. G.; Bertetto, R.; De Benedittis, C.; Yapıcı, H. Basri; Pirisi, M.; Yılmaz, Yusuf; Rigamonti, C. (Elsevier, 2024)

  ...

• Impact of comorbid polycystic ovary syndrome on clinical and laboratory parameters in female adolescents with metabolic dysfunction-associated steatotic liver disease: a cross-sectional study 

  Keskin, Murat; Arsoy, Hanife Aysegül; Kara, Özlem; Sarandol, Emre; Koca, Nizameddin; Yılmaz, Yusuf (MDPI, 2024)

  Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and polycystic ovary syndrome (PCOS) share several pathophysiological mechanisms. While the prevalence of MASLD has been extensively studied in ...

• The relationship between liver fibrosis scores and ascending aortic dilatation 

  Duman, Hakan; Durak, Hüseyin; İpek, Emrah; Duman, Handan; Şahin, Müjgan Ayşenur (Medical University Press, 2024)

  Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is related to an increased atherosclerotic cardiovascular disease (ASCVD) risk. This study investigated a potential relationship between liver fibrosis scores ...

• Magnification of anxiety sensitivity, alexithymia, anger and bodily sensations in patients with migraine headache 

  Polat, Selim; Hocaoğlu, Çiçek; Kırbaş, Serkan; Tüfekçi, Ahmet (Cukurova University, 2024)

  Purpose: In this study, alexithymia, anxiety sensitivity, exaggerated physical sensations and anger expression in patients with migraine headache were compared with a healthy control group. Material and Methods: A total ...

• White tea consumption alleviates anthropometric and metabolic parameters in obese patients 

  Akyıldız, Kerimali; Yılmaz, Adnan; Avcı, Uğur; Toraman, Merve Nur; Yazıcı, Zihni Açar (MDPI, 2024)

  Background and Objectives: Obesity and related disorders are an increasing global health problem. Achieving and maintaining long-term weight loss through lifestyle changes and/or pharmacological interventions have not met ...

• New approaches based on inflammatory indexes in the evaluation of the neoplastic potential of colon polyps 

  Çiftel, Sedat; Çiftel, Serpil; Klisic, Aleksandra; Mercantepe, Filiz (MDPI, 2024)

  Colorectal polyps, precursors to colorectal cancer (CRC), require precise identification for appropriate diagnosis and therapy. This study aims to investigate the differences in hematological and inflammatory markers, ...

• Protective effects of trimetazidine and dexmedetomidine on liver injury in a mesenteric artery ischemia–reperfusion rat model via endoplasmic reticulum stress 

  Çiftel, Sedat; Mercantepe, Tolga; Aktepe, Rıza; Pınarbaş, Esra; Özden, Zülkar; Yılmaz, Adnan; Mercantepe, Filiz (MDPI, 2024)

  Background/Objectives: Acute mesenteric ischemia can lead to severe liver damage due to ischemia–reperfusion (I/R) injury. This study investigated the protective effects of trimetazidine (TMZ) and dexmedetomidine (DEX) ...

• Secukinumab may be an effective treatment option for axial spondyloarthritis and psoriatic arthritis patients with a history of malignancy: multicenter real-life experience from Turkey 

  Ocak, Tuğba; Yağız, Burcu; Ocak, Birol; Yoğurtçu, Özge; Başıbüyük, Fatma; Tezcan, Dilek; Ermurat, Selime; İnanç, Elif; Yamancan, Gülşah; Albayrak, Fatih; Sağır, Rabia Pişkin; Bayındır Akbaş, Ayşe Nur; Cüre, Osman; Coşkun, Belkıs Nihan; Yolbaş, Servet; Karasu, Uğur; Kısacık, Bünyamin; Koca, Süleyman Serdar; Sarı, İsmail; Akar, Servet; Pehlivan, Yavuz (MDPI, 2024)

  Background: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis. Treating axSpA and PsA patients with a history ...

• Investigating the hepatic response to orlistat and white tea in rats on a high-fat diet 

  Çiftel; Klisic, Aleksandra; Çiftel, Enver; Mercantepe, Tolga; Yılmaz, Adnan; Çiftel, Sedat; Pınarbaş, Esra; Toraman, Merve Nur; Mercantepe, Filiz (MDPI, 2024)

  High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and ...

• Cardiovascular risk in patients with ankylosing spondylitis 

  Klisic, Aleksandra; Kotur-Stevuljevic, Jelena; Cüre, Osman; Kızılkaya, Bayram; Çeliker, Fatma Beyazal; Er, Hüseyin; Mercantepe, Filiz (MDPI, 2024)

  Objectives: Ankylosing spondylitis (AS) is an autoinflammatory, chronic disease. Patients with AS are at increased risk of cardiovascular disease (CVD). The link between AS and subclinical atherosclerosis is multifactorial ...

• The nephroprotective effect of punica granatum peel extract on LPS-induced acute kidney injury 

  Şahin Aktura, Sena; Şahin, Kazım; Tümkaya, Levent; Mercantepe, Tolga; Topçu, Atilla; Pınarbaş, Esra; Yazıcı, Zihni Açar (MDPI, 2024)

  Sepsis is an exaggerated immune response resulting from systemic inflammation, which can damage tissues and organs. Acute kidney injury has been detected in at least one-third of patients with sepsis. Sepsis-associated ...

• Acute stroke organization in emergency services 

  Yazıcı, Mümin Murat (Nova Science Publishers, Inc., 2024)

  Health systems worldwide categorize health facilities according to the feasibility of acute stroke treatment and, if feasible, the level of this treatment. This type of organization starts with screening, identifying, and ...

• An effective treatment for progressive keratoconus with two-year outcomes: accelerated epithelium-on corneal cross-linking 

  Kaim, Muhammet; Okutucu, Murat; Fındık, Hüseyin; Uzun, Feyzahan (Pamukkale University, 2024)

  Purpose: Corneal collagen cross-linking (CXL) is a surgical technique for progressive keratoconus. There are several technical modifications with varying clinical outcomes. This study aimed to evaluate the long-term outcomes ...

• Clinical value of systemic immune inflammation and pan-immune inflammation in adenoid hypertrophy 

  Yemiş, Tuğba; Birinci, Mehmet; Çeliker, Metin; Balaban, Gökçe Aydın; Askeroğlu, Erdal Eren; Erdivanlı, Özlem Çelebi (Galenos Publishing, 2024)

  Aim: This study aimed to investigate the relationship between adenoid hypertrophy, the most common cause of obstructive sleep apnea (OSA) in children, with the systemic immune inflammation index (SII) and the pan-immune ...

• Biochemical markers and carotid intima-media thickness in relation to cardiovascular risk in young women 

  Klisic, Aleksandra; Kotur-Stevuljevic, Jelena; Gluscevic, Sanja; Şahin, Serap Baydur; Mercantepe, Filiz (Nature Research, 2024)

  Cardiovascular disease (CVD) is a major cause of death in the female population. The current study aimed to examine the relationship between CVD risk and novel endothelial dysfunction biomarkers [i.e., endocan, adiponectin ...

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