Kurum Yazarı "Tomak, Yakup" Tıp Fakültesi İçin Listeleme
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Analysis of the effect of perioperative magnesium sulphate on minimal alveolar concentration of desflurane using bispectral index monitoring
Background. In this study we aimed to analyze the effect of perioperative magnesium sulphate (MgSO4) on minimal alveolar concentration (MAC) of desflurane using bispectral index (BIS) monitoring. Patients and methods. Sixty ... -
Anestezi yoğun bakım ünitesinde ventilatör ilişkili pnömoni hızları ve etken mikroorganizmaların dağılımı
Amaç: Yoğun Bakım Ünitelerinde en sık görülen nozokomiyal enfeksiyon pnömonidir. Nozokomiyal pnömonilerin önemli kısmını oluşturan ventilatör ilişkili pnömoniler (VİP) önemli morbidite ve mortalite nedenidir. VIP oranı ve ... -
Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality
Çilli, Aykut; Erdem, Hakan; Karakurt, Zuhal; Türkan, Hülya; Yazicioğlu-Mocin, Ozlem; Adıgüzel, Nalan; Güngör, Gökay; Bilge, Uğur; Taşcı, Cantürk; Yılmaz, Gülden; Öncül, Oral; Doğan Çelik, Aygül; Erdemli, Özcan; Öztoprak, Nefise; Samur, Anıl Aktaş; Tomak, Yakup; İnan, Asuman; Karaboğa, Burcu; Tok, Demet; Temur, Sibel; Öksüz, Hafize; Şentürk, Özgür; Büyükocak, Ünase; Yılmaz Karadağ, Fatma; Özcengiz, Dilek; Karakaş, Ahmet; Savaşcı, Ümit; Özgen Alpaydın, Aylin; Kılıç, Erol; Elaldi, Nazif; Bilgiç, Hayati (W B Saunders Co-Elsevier Inc, 2013)Purpose: the aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission ... -
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells
Kalkan, Yıldıray; Bostan, Habib; Tümkaya, Levent; Tomak, Yakup; Bostan, Mehmet; Yılmaz, Adnan; Türüt, Hasan; Temiz, Ahmet; Yalçın, Alper; Turan, Alparslan (Springer Link, 2012)Purpose: Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of ... -
Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Altuner, Durdu; Yılmaz, Adnan; Erdivanlı, Başar; Bedir, Recep; Yalçın, Alper; Turan, Alparslan (Sage Publications Inc, 2015)Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ... -
Effects of sugammadex and rocuronium mast cell number and degranulation in rat liver
Tomak, Yakup; Yılmaz, Adnan; Bostan, Habib; Tümkaya, Levent; Altuner, Durdu; Kalkan, Yıldıray; Erdivablı, Başar (Wiley, 2012)We investigated the effect of rocuronium- and sugammadex-induced mast cell increase and degranulation in rat portal triads. Forty-two rats, in six groups, received either rocuronium 1 mg.kg -1; sugammadex 15 mg.kg -1; ... -
Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study
Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Yılmaz, Adnan (Springer, 2012)Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ... -
Glutaminesupplemented parenteral nutritionto prevent ventilator- associated pneumonia in the intensive care unit
Aydoğmuş, Meltem Türkay; Tomak, Yakup; Tekin, Murat; Katı, İsmail; Hüseyinoğlu, Urfettin (Galenos Publishing House, 2012)Objective: Ventilator-associated pneumonia (VAP) is a form of nosocomial pneumonia that increases patient morbidity and mortality, length of hospita stay, and healthcare costs. Glutamine preserves the intestinal mucosal ... -
Hepatic effects of ketamine administration for 2 weeks in rats
Kalkan, Yıldıray; Tomak, Yakup; Altuner, Durdu; Tümkaya, Levent; Bostan, Habib; Yılmaz, Adnan; Ünal, D.; Kara, A.; Turan, A. (Sage Publishing, 2014)The aim of the present study was to investigate the long-term and high-dose application of ketamine on the liver by employing histologic and biochemical methods. A total of 30 male rats were randomly assigned to control ... -
Influence of intracoronary shunt on myocardial ischemic injury during off-pump coronary artery bypass surgery
Bozok, Şahin; İlhan, Gökhan; Karamustafa, H.; Karakişi, Sedat Ozan; Tüfekçi, N.; Tomak, Yakup; Bağcı, P.; Emir, M.; Şener, E. (2013)Aim. The aim of the study was to evaluate the role of intracoronary shunt during off-pump coronary artery bypass surgery in patients with isolated left anterior descending coronary artery lesion. Methods. Forty patients ... -
Internal urethrotomy under local urethral anaesthesia is feasible with sedation and analgesia
Uzun, Hakkı; Zorba, Orhan Ünal; Tomak, Yakup; Bostan, Habip; Kalkan, Mehmet (Kowsar Medical Publishing Company, 2012)Background: Urethral stricture is a common condition, and direct vision internal urethrotomy is prefered as the first treatment option by many urologists, for strictures shorter than 2 cm. This procedure is generally ... -
Intracranial chronic subdural hematoma occurring six months after spinal anaesthesia: a case report
İntrakranial kronik subdural hematomlar spinal anestezinin nadir görülen komplikasyonudur. Bu yazıda spinal anestezi ile ve sezaryenle doğum yapan 32 yaşındaki bir bayanda doğumdan 6 ay sonra gelişen bir cSDH olgusu ... -
Miyastenia gravisli bir olguda sugammadeks kullanımı
Tomak, Yakup; Bostan, Habib; Kazdal, Hızır (2011)Miyastenia gravis, postsinaptik asetilkolin reseptörlerine karşı antikor gelişimiyle karakterize otoimmün bir hastalıktır. Hastalarda nondepolarizan kas gevşeticilere karşı duyarlılık artmıştır. Sugammadeks, roküronyum ve ... -
A novel model approach for esophageal burns in rats: a comparison of three methods
Kalkan, Yıldıray; Tümkaya, Levent; Akdoğan, Remzi Adnan; Yücel, Ahmet Fikret; Tomak, Yakup; Şehitoğlu, İbrahim; Pergel, Ahmet; Kurt, Aysel (Sage Publications Inc, 2015)Background: Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure. Materials and methods: We conducted ... -
A randomized-controlled, double-blind comparison of the postoperative analgesic efficacy of caudal bupivacaine and levobupivacaine in minor pediatric surgery
Şen, Ahmet; Çolak, Mehmet Salih; Ertürk, Engin; Tomak, Yakup (Korean Society of Anesthesiologists, 2014)Background: We compared the postoperative analgesic efficacy of caudal levobupivacaine with bupivacaine in pediatric subumbilical surgery. Methods: Sixty American Society of Anesthesiologists I-II patients scheduled for ... -
Reversal of rocuronium-induced neuromuscular block with sugammadex and resulting histopathological effects in rat kidneys
Bostan, Habib; Kalkan, Yıldıray; Tomak, Yakup; Tümkaya, Levent; Altuner, Durdu; Yılmaz, Adnan; Erdivanlı, Başar; Bedir, Recep (Taylor & Francis, 2011)Background: This study investigated the effect of injection of rocuronium or sugammadex alone and rocuronium + sugammadex on urea, creatinine, electrolyte levels, and histopathological findings in rats. Methods: Thirty-six ... -
Role of cultural interaction in tianeptine abuse and different application methods
Tianeptine is a selective serotonin reuptake enhancer, possessing strong antidepressant and anxiolytic properties. Its relative lack of sedative, anticholinergic and cardiovascular side effects makes it a highly tolerable ... -
Steroid yapılı nondepolarizan nöromüsküler blokerlere bağlı allerjik reaksiyonlar ve tedavide sugammadeksin rolü
Tomak, Yakup; Erdivanlı, Başar; Şen, Ahmet (2013)Genel anestezi sırasında gelişen anafilaktik ve anafilaktoid reaksiyonların yarıdan fazlası kas gevşetici ajanlar nedeniyle oluşur. Teşhis ve uygun tedavide gecikme nedeniyle yüksek mortalite ve morbiditeyle sonuçlanan bu ... -
Sugammadex use in difficult intubation due to ankylosing spondylitis and severe restrictive respiratory disease
Tomak, Yakup; Bostan, Habib; Erdivanlı, Başar; Şen, Ahmet (2012)Bu yazıda, torasik spinal rekonstrüksiyon operasyonu planlanan, ankilozan spondilite bağlı ağır restriktif akciğer hastalığı ve zor entübasyon bulguları gösteren 50 yaşında erkek hastanın anestezi yönetimi tartışıldı. ...