Kurum Yazarı "Uydu, Hüseyin Avni" Tıp Fakültesi İçin Listeleme
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Acute renal involvement in organophosphate poisoning: histological and immunochemical investigations
Kaya, Yasemin; Baş, Orhan; Hancı, Hatice; Çankaya, Soner; Nalbant,İsmail; Odacı, Ersan; Uydu, Hüseyin Avni; Aslan, Ali (Taylor & Francis Ltd, 2018)Purpose: Today, the long-term effects of partial exposure of cholinesterase on the kidney continue to be a research topic. in this study, we aimed to histopathologically investigate the possible effect of acute toxicity ... -
Association between plasma monocyte chemoattractant protein-1 levels and the extent of atherosclerotic peripheral artery disease
Şatıroğlu, Ömer; Uydu, Hüseyin Avni; Demir, Adem; Bostan, Mehmet; Atak, Mehtap; Bozkurt, Engin (2011)Peripheral artery disease occurs at advanced ages and accounts for substantial cardiovascular morbidity and mortality. Monocyte chemoattractant protein-1 (MCP-1), a member of the cysteine-cysteine family of chemokines, is ... -
The cardioprotective effects of perindopril in a model of polymicrobial sepsis: The role of radical oxygen species and the inflammation pathway
Topçu, Atilla; Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya K.; Tümkaya, Levent; Uydu, Hüseyin Avni (Wiley, 2022)Mortality rates associated with myocardial dysfunction due to sepsis and septic shock are generally high across the world. The present study focused on the antioxidant and anti-inflammatory effects of perindopril (PER) for ... -
Cholesterol forms and traditional lipid profile for projection of atherogenic dyslipidemia: lipoprotein subfractions and erythrocyte membrane cholesterol
Uydu, Hüseyin Avni; Bostan, Mehmet; Atak, Mehtap; Yılmaz, Adnan; Demir, Adem; Akcan, Buket; Sümer, Fatih; Baltaş, Nimet; Karadağ, Zakir; Uğurlu, Yavuz; Örem, Asım (Springer, 2014)Atherogenic dyslipidemia characterized by abnormal changes in plasma lipid profile such as low high-density lipoprotein (HDL) and increased triglyceride (TG) levels is strongly associated with atherosclerotic diseases. We ... -
Diagnostic value of serum signal peptide-CUB-EGF-like domain- containing protein 1 levels in patients with acute appendicitis
Altuntaş, Gürkan; Altuntaş, Mehmet; İmamoğlu, Melih; Çolakoğlu, Muhammed Kadri; Uydu, Hüseyin Avni; Bedir, Recep (Assoc Medica Brasileira, 2023)OBJECTIVE: Acute appendicitis is one of the most common surgical causes of an acute abdomen among patients admitted to the emergency room due to abdominal pain. The clinical diagnosis of acute appendicitis is usually ... -
Distribution of coronary artery risk factors: a regional analysis
Bostan, Mehmet; Şatıroğlu, Ömer; Uydu, Hüseyin Avni; Çiçek, Yüksel; Çanğa, Aytun; Karadağ, Zakir; Temiz, Ahmet; Uǧurlu, Yavuz; Atak, Mehtap; Bozkurt, Engin (2011)Amaç: Bu çalışmadaki amacımız, Rize ili ve civarında koroner arter risk faktörlerinin sıklık ve dağılımını incelemektir. Yöntem ve gereç: Bu gözlemsel çalışmaya, 452 hasta (333 erkek, 119 kadın) alındı. Hastaların demografi ... -
The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology
Baş, Orhan; Çankaya, Soner; Enginyurt, Özgür; Aslan, Ali; Uydu, Hüseyin Avni; Odacı, Ersan; Yılmaz, Ali; Demir, Adem; Gül, Tuba (Elsevier, 2019)Background: the most commonly used insecticides and pesticides worldwide are organophosphate compounds, chemicals that irreversibly inhibit the cholinesterase enzyme. Acute intoxication with cholinesterase inhibitors is ... -
The effect of imatinib administered in the prenatal period on testis development in rats
Suzan, Zehra Topal; Tümkaya, Levent; Mercantepe, Tolga; Atak, Muhammed; Uydu, Hüseyin Avni (Sage Publications Ltd, 2021)Background: the purpose of this study was to examine the effects of exposure to imatinib in the prenatal period on testis development in rats. Methods: Although all the study groups received intraperitoneal imatinib on ... -
Effect of white tea consumption on serum leptin, TNF-alpha and UCP1 gene expression in ovariectomized rats
Saral, Sinan; Saydam, Faruk; Dokumacıoğlu, Eda; Atak, Mehtap; Tümkaya, Levent; Uydu, Hüseyin Avni (John Libbey Eurotext Ltd., 2021)Background: Obesity and dyslipidemia due to estrogen deficiency are among the important health problems in menopausal women. Increasing evidence reports the anti-obesity and anti-hyperlipidemic properties of tea polyphenols. ... -
The effects of Atorvastatin Therapy on rheological characteristics of erythrocyte Membrane, serum lipid profile and oxidative status in patients with dyslipidemia
Uydu, Hüseyin Avni; Yıldırmış, Sermet; Örem, Cihan; Çalapoğlu, Mustafa; Alver, Ahmet; Kural, Birgül; Örem, Asım (Springer, 2012)The statins, most commonly used in the treatment of hyperlipidemia, have certain beneficial effects including improved endothelial function, plaque stability and decreased oxidative stress and inflammation, beyond their ... -
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
Şen, Ahmet; Erdivanlı, Başar; Tümkaya, Levent; Uydu, Hüseyin Avni; Mercantepe, Tolga; Batçık, Şule; Özdemir, Abdullah (Taylor & Francis Ltd., 2023)Background: The objective of this study was to investigate the effect of dexmedetomidine (Dex), a sedative drug with little or no depressant effect on respiratory centers, on secondary injury in rat brain tissue by means ... -
The effects of white tea (Camellia Sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis
Çakıroğlu, Şenay; Mercantepe, Tolga; Tümkaya, Levent; Uydu, Hüseyin Avni; Topçu, Atilla; Atak, Mehtap (2023)Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, ... -
Investigation of some biological active properties of Anzer bee-pollen
Efe, Hasan; Çakır, Hilal Ebru; Kolaylı, Sevgi; Yılmaz, Adnan; Uydu, Hüseyin Avni (Wiley-Blackwell, 2016)... -
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
Topçu, Atilla; Balık, Gülşah; Atak, Mehtap; Mercantepe, Tolga; Uydu, Hüseyin Avni; Tümkaya, Levent (Elsevier, 2019)Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ... -
An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats
Topçu, Atilla; Mercantepe, Filiz; Rakıcı, Sema; Tümkaya, Levent; Uydu, Hüseyin Avni; Mercantepe, Tolga (Springer, 2019)According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ... -
Lasting hepatotoxic effects of prenatal mobile phone exposure
Yılmaz, Adnan; Tümkaya, Levent; Akyıldız, Kerimali; Kalkan, Yıldıray; Bodur, Ali Fuat; Sargın, Fatma; Efe, Hasan; Uydu, Hüseyin Avni; Yazıcı, Zihni Açar (Taylor & Francis Ltd, 2017)Objective: in this study, the livers of rats born to mothers exposed to electromagnetic field (EMF) were examined 60 days postpartum for biochemical and histopathological changes.Methods: Pregnant rats were exposed to ... -
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
Batçık, Şule; Tümkaya, Levent; Mercantepe, Tolga; Atak, Mehtap; Topçu, Atilla; Uydu, Hüseyin Avni; Mercantepe, F. (Verduci Editore, 2022)OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ... -
Neuroprotective effects of Vaccinium myrtillus on damage-related brain injury
Özdemir, Abdullah; Mercantepe, Tolga; Erdivanlı, Başar; Şen, Ahmet; Mercantepe, Filiz; Tümkaya, Levent; Uydu, Hüseyin Avni (2023)Traumatic brain injury may trigger the secondary brain injury, which has the potential to be reversible and thus preventable. Anthocyanins are phylotherapeutic plants, which are reported to exhibit anti-inflammatory ... -
Pleiotropic effects of HDL subfractions and HDL-associated enzymes on protection against coronary artery disease
Bostan, Mehmet; Uydu, Hüseyin Avni; Karadağ, Zakir; Atak, Mehtap; Uğurlu, Yavuz; Ergül, Elif; Şatıroğlu, Ömer; Yılmaz, Adnan (Taylor & Francis Ltd, 2015)Objective High-density lipoprotein cholesterol (HDL-C) levels are inversely related to the risk of coronary artery disease (CAD). Alterations in HDL-C subclass distribution and HDL-associated enzyme activities may be more ...