Tıp Fakültesi: Recent submissions
Now showing items 101-120 of 2937
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Gastrointestinal system involvement characteristics in Covid -19 patients
(Pakistan Medical Association, 2025)Objective: To evaluate the involvement of gastrointestinal tract features in patients of coronavirus disease-2019, and to analyse the effects of these features on the development of critical illness, macrophage activation ... -
Ultrasound evaluation of gastric emptying and comparison with patient-reported risk factors in elective surgical patients
(MDPI, 2025)Background/Objectives: Despite standard preoperative fasting guidelines, residual gastric content can persist in some patients, increasing the risk of aspiration pneumonitis. Multiple patient-specific factors may predict ... -
Predicting semen analysis parameters from testicular ultrasonography images using deep learning algorithms: an innovative approach to male infertility diagnosis
(MDPI, 2025)Objectives: Semen analysis is universally regarded as the gold standard for diagnosing male infertility, while ultrasonography plays a vital role as a complementary diagnostic tool. This study aims to assess the effectiveness ... -
Differences in microorganism profile in periprosthetic joint infections of the knee in patients affected by chronic kidney disease
(Elsevier, 2025)Background: Periprosthetic joint infections (PJIs) are one of the most devastating complications of total knee arthroplasty (TKA). Patients who have chronic kidney disease (CKD) are more vulnerable to PJI. We aimed to ... -
Comparison of search and rescue operations involving emergency physicians in devastating earthquakes in Turkey: a 24-year experience study
(BMC, 2025)Background: In the 21st century, disasters (particularly earthquakes, which remain the leading cause of death) continue to be among the foremost issues requiring global emergency response. While the impact of advancing ... -
Medical management pathways for Cushing's disease in pituitary tumors centers of excellence (PTCOEs)
(Springer, 2025)PurposeA recent update of consensus guidelines for the management of Cushing's disease (CD) included indications for medical therapy. However, there is limited evidence regarding their implementation in clinical practice. ... -
The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome
(BMC, 2025)BackgroundPlacental syndrome, mainly composed of preeclampsia and fetal growth restriction, has an impact on the health of mother and baby dyads. While impaired placentation is central to their pathophysiology, the underlying ... -
Role of coagulation factors in hepatocellular carcinoma: a literature review
(MDPI, 2025)Hepatocyte carcinoma (HCC) is a globally prevalent neoplasm with profound effects on morbidity and mortality rates. This review summarizes the complex interactions between coagulation abnormalities and the pathophysiological ... -
Evaluation of retinal changes in women with different phenotypes of polycystic ovary syndrome
(MDPI, 2025)Background: The aim of our study was to evaluate the retinal nerve fiber layer (RNFL) and macular and choroidal thicknesses in women with different phenotypes of polycystic ovary syndrome (PCOS), and compare these measurements ... -
Investigation of ITGB3 heterogeneity to overcome trastuzumab resistance in HER2-positive breast cancer
(MDPI, 2025)HER2-positive breast cancer has an aggressive tumour progression among breast cancers characterized by the overexpression of HER2. Trastuzumab is an FDA-approved drug and has significantly improved outcomes for patients; ... -
Identification and characterization of a novel rat MAVS variant modulating NFκB signaling
(MDPI, 2025)The innate immune response serves as the primary defense against viral infections, with the recognition of viral nucleic acids by pattern recognition receptors (PRRs) initiating antiviral responses. Mitochondrial ... -
Is punica granatum efficient against sepsis? A comparative study of amifostine versus pomegranate
(MDPI, 2025)Sepsis is a clinical condition causing tissue damage as a result of infection and an exaggerated immune response. Sepsis causes 11 million deaths annually, a third of which are associated with acute lung injury (ALI). Rapid ... -
Investigation of the effects of fosfomycin in kidney damage caused by CLP-induced sepsis
(MDPI, 2025)Sepsis, a life-threatening condition characterized by dysregulated host responses to infection, often leads to multi-organ dysfunction, including kidney injury. Kidney damage in sepsis can have severe consequences and is ... -
Investigation of the preventive effect of methylsulfonylmethane on alveolar bone loss and oxidative stress in a rat model of periodontitis
(BMC, 2025)Background To investigate the preventive efficacy of methylsulfonylmethane (MSM) on alveolar bone destruction in rats with periodontitis. Methods Twenty-four male Sprague-Dawley rats were randomly divided into three groups: ... -
Effects of 5 G mobile phone network electromagnetic field exposure on testicular endoplasmic reticulum stress and the protective role of coenzyme Q10
(Elsevier, 2025)Aim. Nowadays, the electromagnetic field (EMF) has become an issue of electromagnetic pollution . This study aimed to determine the effect of 5 G Fr1 frequency band EMF waves on endoplasmic reticulum (ER) stress in testicular ... -
A pilot study assessing left ventricle diastolic function in the parasternal long-axis view
(eScholarship, 2025)Introduction: Spectral Doppler echocardiography is used to evaluate diastolic dysfunction of the heart. However, it is difficult to assess diastolic function with this modality in emergency department (ED) settings. Based ... -
Notch and hedgehog signalling axis drive senescence in HER2-positive breast cancer resistant to trastuzumab
(Istanbul University Press, 2024)Objective: Cellular senescence halts the proliferation of damaged or preneoplastic cells, playing a vital role in cancer control. In HER2-positive breast cancer, resistance to trastuzumab, a HER2-targeted monoclonal antibody, ... -
Evaluation of the frequency and clinical features of comorbid adult separation anxiety disorder in patients with generalized anxiety disorder
(ANP Publishing, 2024)Objective: The aim of this study is to examine the frequency and clinical features of comorbid Adult Separation Anxiety Disorder (ASAD) in patients with Generalized Anxiety Disorder (GAD). Method: A total of 80 patients ... -
The impact of the trigger day progesterone, luteinizing hormone and their interaction on live birth rates in GnRH antagonist cycles
(Wiley, 2025)Aim: This study aims to assess the impacts of various trigger day progesterone (P4) and luteinizing hormone (LH) levels on live birth rates (LBRs) in fresh in vitro fertilization (IVF) cycles, considering their elevation ...
