Başlık için FEF, Kimya Bölümü Koleksiyonu listeleme
Toplam kayıt 441, listelenen: 58-77
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Design and synthesis of benzimidazole derivatives as apoptosis-inducing agents by targeting Bcl-2 protein
(Springer, 2022)Bcl-2, an anti-apoptotic protein, is a well-known and appealing cancer therapy target. Novel series of benzimidazole derivatives were synthesized and tested for their activity as Bcl-2 inhibitors on T98G glioblastoma, PC3 ... -
Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
(Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Design, synthesis and biological evaluation of water soluble and non-aggregated silicon phthalocyanines, naphthalocyanines against A549, SNU-398, SK-MEL128, DU-145, BT-20 and HFC cell lines as potential anticancer agents
(Elsevier, 2021)Cancer has become an important public problem in worldwide since cancer incidence and mortality are growing rapidly. In this study, water soluble and non-aggregated silicon (IV) phthalocyanines and naphthalocyanines ... -
Design, synthesis, and biological evaluation of coumarin-triazole hybrid molecules as potential antitumor and pancreatic lipase agents
(Wiley-V C H Verlag Gmbh, 2017)The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ... -
Design, synthesis, and characterization of some new benzimidazole derivatives and biological evaluation
(Wiley, 2020)A new series of benzimidazole derivatives (1-15) containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and thiazolidinon rings have been synthesized. All new synthesized benzimidazole compounds were confirmed by ... -
Designing bipyridine-functionalized zirconium metal-organic frameworks as a platform for clean energy and other emerging applications
(Elsevier Science Sa, 2018)Metal-organic frameworks (MOFs) are a class of crystalline and porous materials with modular structural features. This modularity has allowed MOFs to be designed and synthesized with adjustable pore sizes and shapes leading ... -
Detection of Fe2+ in acetonitrile/water mixture by new 8-hydroxyquinolin based sensor through metal displacement mechanism
(Elsevier Science Bv, 2017)A 8-hydroxyquinoline-based (8-HQ) fluorescent ligand (2) was designed and synthesized by condensation of pyridine-2-carboxaldehide with 2-(quinolin-8-yloxy)acetohydrazide (1). Fluorometric titrations with various metal ... -
Determination of adsorptive properties of a Turkish Sepiolite for removal of Reactive Blue 15 anionic dye from aqueous solutions
(Elsevier, 2009)Reactive Blue 15 (RB 15) adsorption on the Turkish Sepiolite was carried out by batch equilibrium technique. IR spectrum and surface area measurement of the composite of dye-sepiolite (Turkish) pointed out that dye species ... -
Determination of biological activities and pka at drug active substance in some bisbenzimidazoles derivatives
(Raman Publ, 2016)Bisbenzimidazole derivatives have known different structures as drug active substance were evaluated for their biological activities such as antiviral and anti-tumor activities. in addition, acid dissociation constants ... -
Determination of color additive tartrazine (E 102) in food samples after dispersive solid phase extraction with a zirconium-based metal-organic framework (UiO-66(Zr)-(COOH)(2))
(Taylor & Francis Ltd, 2020)A new and rapid dispersive solid phase extraction method by using a green-synthesised UiO-66(Zr)-(COOH)(2) (Zr-BTeC) adsorbent with body-centred cubic (bcu) topology was developed for determination of tartrazine in food ... -
Determination of epinephrine in human serum using a Pt electrode modified by polyaniline-poly(3-methylthiophene)-poly(3,3 '-diaminobenzidine)
(Canadian Science Publishing, Nrc Research Press, 2015)A Pt electrode modified by polyaniline-poly(3-methylthiophene)-poly(3,3'-diaminobenzidine) was used for amperometric determination of epinephrine in a solution of NaHSO4/Na2SO4 (pH 2.0). For these studies, potentials between ... -
Determination of hydroquinone using Poly(3-methylthiophene) hynthesized electrochemically on Pt electrode in methylene chloride
(Wiley-Blackwell, 2014)Poly(3-methylthiophene) (P3MT) film was synthesized by potentiodynamic method on Pt electrode in methylene chloride solution containing 0.10M tetrabuthlammonium perchlorate supporting electrolyte and used for the determination ... -
Determination of protonation constants of some 3-alkyl(aryl)-4-(ptert- butyl(benzyl/benzyliden)amino)-4,5-dihydro-1H-1,2,4-triazole-5- one deriveatives with spectrophotometric method
(2011)The protonation constant values of different twelve 3-alkyl(aryl)-4-(p-t-butyl(benzyl/ benzyliden)amino)-4,5-dihydro-1H-1,2,4-triazole-5-one derivatives have been determined in ethanol %50 - water %50 mixtures by ... -
Determination of the pKa of Some triazole derivatives by the potentiometric method in dioxan-water mixtures
(2011)Stoichiometric protonation constants of some 3-alkyl(aryl)-4-(substituted benzylamino)-4,5-dihydro-1 H-1,2,4-triazol-5-ones derivatives were determined potentiometrically in 50% (v/v) dioxan-water mixtures at 25°C with an ... -
Determination of the pKa value of some 1,2,4-triazol derivatives in forty seven different solvents using semi-empirical quantum methods (PM7, PM6, PM6-DH2, RM1, PM3, AM1, and MNDO) by MOPAC computer program
(Ovidius University Press, 2023)In this study, we calculated the enthalpy (?H, kcal/mol), entropy (?S, cal/K.mol) and free energy (?G, kcal/mol) thermodynamic values of each molecule for forty-seven different solvent media according to semi-empirical ... -
Determination of the protonation constants of some 4-(substituted benzylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones by the potentiometric method in ethanol-water mixtures
(2007)To gain more information about the effect of solvent on 4,5-dihydro-1H-1,2,4-triazol-5-ones, the stoichiometric protonation constants of thirteen triazoles in ethanol-water mixtures were determined at an ionic strength of ... -
Determination of the protonation constants of triazole derivatives in non-aqueous solvents
(2009)Different 17 triazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, rert-butyl alcohol, N,N-dimethylformamide and acetonitrile), using Potentiometric method. ... -
Determining the levels of acrylamide in some traditional foods unique to Turkey and risk assessment
(Brieflands, 2022)In this study, exposure risk assessment was made by determining the acrylamide levels of some traditional foods frequently consumed by the Turkish society and registered geographical indication. For this purpose, acrylamide ... -
Developing a scaffold for urease inhibition based on benzothiazoles: Synthesis, docking analysis, and therapeutic potential
(Wiley-V C Verlag GMBH, 2021)The synthesis, in silico molecular docking, and in vitro urease inhibition studies of a novel series of benzothiazole derivatives are reported. The title compounds in the two series, namely, 2-({5-[(benzothiazol-2-ylthio ... -
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
(Wiley, 2024)In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ...
