Güncel Gönderiler: FEF, Kimya Bölümü Koleksiyonu
Toplam kayıt 455, listelenen: 21-40
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Efficient, rapid, and high-yield synthesis of aryl Schiff base derivatives and their in vitro and in silico inhibition studies of hCA I, hCA II, AChE, and BuChE
(Wiley, 2024)This study reports a rapid and efficient synthesis of four novel aryl Schiff base derivatives. Biological activity and molecular modeling studies were conducted to evaluate the inhibitory effects of these compounds on human ... -
A facile ultrasonic synthesis approach to 3-H-quinazolinethione derivatives and their urease inhibition studies
(Taylor & Francis Ltd., 2024)In this study, a new series of 3H-quinazoline-4-thione derivatives were synthesized under ultrasonic irradiation conditions with high yield in a short time. The new compounds were characterized by FT-IR,H-1, and C-13 NMR ... -
Some schiff bases containing eugenol and guaiacol: Comparison of urease inhibition and anti-helicobacter pylori activities with Its azo analogs
(Springer, 2024)To improve and develop our monotherapeutic approach for Helicobacter pylori infection, some Schiff base compounds containing eugenol and guaiacol were synthesized and their antioxidant capacities, urease enzyme inhibition, ... -
Effect of environmental pollution on nutritional indices and the phenoloxidase activity of agelastica alni (Coleoptera: Chrysomelidae) larvae
(Springer, 2024)Abstract: The present study investigated the nutritional indices and immune responses of Agelastica alni L. larvae in heavy metal pollution (cadmium, zinc, copper, nickel, and iron). Larvae collected from 2 different ... -
Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity
(Elsevier, 2024)Existing drugs that are being used to treat type-2 diabetes mellitus are associated with several side effects; thus, exploring potential drug candidates is still an utter need these days. Hybrids of indenoquinoxaline and ... -
Synthesis of benzimidazoles containing piperazine ring as potential therapeutic agents against diabetes mellitus and antioxidant activities
(Elsevier, 2024)We synthesized a novel 6-(4-substitue-piperazin-1-yl)-2-aryl-1H-benzimidazole derivatives starting from 5-(4-substitue-piperazin-1-yl)-2-nitroaniline with different aldehydes. A quick "onepot" nitro reductive cyclization ... -
Synthesis and biological evaluation of coumarin-amino acid-benzotriazole conjugates
(Springer, 2024)Objective: It is aimed to synthesize new amino acid-conjugated coumarin-benzotriazole molecules and to investigate their acetylcholinesterase, urease, and lipase inhibition properties. Methods: Urease inhibitory activities ... -
Developing effective antimicrobial agents: synthesis and molecular docking study of ciprofloxacin-benzimidazole hybrids
(Wiley, 2024)In this study, we designed and synthesized some new ciprofloxacin-benzimidazole hybrid compounds and evaluated them for their antimicrobial activity against four Gram-positive (B. subtilis, B. megaterium, E. faecalis and ... -
Theoretical determination of electronic, geometric and spectroscopic properties of some 1,2,4-triazol derivatives
(2023)In this study, molecular geometric optimization of five 4,5-dihydro-1H-1,2,4-triazol-5-one derivative compounds was obtained using Density Functional Theory, (DFT, B3LYP)/ Hartree Fock, (HF, B3LYP) methods on the basis set ... -
Cellulose ester-based aerogel: lightweight and highly water-absorbent
(American Chemical Society, 2023)Cellulose was extracted from waste generated by pruning tea stem wastes. The interaction between pure cellulose and homophthalic acid produced a light (0.22 g·cm-3) and eco-friendly hybrid aerogel product that is highly ... -
Human health risk assessment of heavy metals accumulation in different genders and tissues of whiting fish (Merlangius merlangus euxinus Nordmann, 1840) from Rize, Turkey
(Elsevier, 2024)The contamination of fish resulting from marine pollution is a major concern, as it poses potential adverse effects on human health. Therefore, heavy metal concentrations (Cr, Fe, Ni, Cu, Zn, and Pb) in different genders ... -
Effect of Usnea longissima ethyl acetate extract on acute oxidative and inflammatory lung damage from Staphylococcus aureus infection in rats
(University of South Bohemia in Ceske Budejovice Faculty of Health and Social Sciences, 2023)The role of oxidants and proinflammatory cytokines in the pathogenesis of pneumonia caused by Staphylococcus aureus (S. aureus) has been demonstrated. The present study aims to investigate the protective effect of ethyl ... -
Synthesis of some benzimidazole-thiophene hybrids as potential urease and lipase inhibitors
(Springer Link, 2023)In this study, some benzimidazole-thiophene hybrid compounds containing isatin and salicyl moieties were synthesized and investigated for their urease and lipase inhibition properties. Most of the synthesized compounds ... -
Stereo- and Regio-selective benzo- and Benzohalo-conduritols: Anti-diabetes & anti-tumor activity investigation, kinetic and molecular docking studies
(Elsevier, 2023)In this study, benzoconduritols, benzohalogenoconduritol, and benzodihalogenoconduritols with conduritol-A and –C structures from oxo-norbornene derivative endo-10 b, exo-11 b cleavaged by Lewis acids (BBr3, BCl3, BF3· ... -
Multicomponent diastereoselective synthesis of tetrahydropyridines as α-amylase and α-glucosidase enzymes inhibitors
(2023)Background: Researchers seeking new drug candidates to treat diabetes mellitus have been exploring bioactive molecules found in nature, particularly tetrahydropyridines (THPs). Methods: A library of THPs (1–31) were ... -
A facile and sensitive coprecipitation method coupled with flame atomic absorption spectrometry for quantification of Cu(II) ions in complex matrices
(Serbian Chemical Society, 2023)In the present investigation, the application of an organic coprecipitant, 2-[5,6-dichloro-2-(2-bromobenzyl)-1H-benzimidazole-1-yl]acetohydrazide (DIBBA), for separation and preconcentration of Cu(II) ions in fruit and ... -
Benzimidazolone-piperazine/triazole/thiadiazole/furan/thiophene conjugates: Synthesis, in vitro urease inhibition, and in silico molecular docking studies
(Wiley, 2023)This study describes the synthesis, in vitro urease inhibition, and molecular docking studies of benzimidazolone derivatives incorporating the piperazine, triazole, thiadiazole, furan, thiophene, and thiosemicarbazide ... -
Diastereoselective synthesis, characterization, investigation of anticancer, antibacterial activities, in silico approaches and DNA/BSA binding affinities of novel pyrimidine-sugar derivatives
(Elsevier, 2023)Eighteen novel carbohydrate conjugates (1-9) and their tetra-O-acetyl derivatives (10-18) were synthesized in total and evaluated for their biological properties, including antimicrobial and anticancer functions, and ... -
Staphylococcus aureus bacteriophage 52 endolysin exhibits anti-biofilm and broad antibacterial activity against gram-positive bacteria
(Springer, 2023)Bacteriophage endolysins have been shown to hold great promise as new antibacterial agents for animal and human health in food preservation. In the present study, endolysin from Staphylococcus aureus subsp. aureus ATCC ... -
Microplastics in branded milk: Dietary exposure and risk assessment
(Elsevier, 2023)In this study, 14 packaged milk of various brands sold in the Türkiye market was examined. The microplastics were physically characterised under the microscope. Their vibrational spectra were recorded with the ATF/FT-IR ...