Kurum Yazarı "Rakıcı, Sema Yılmaz" TF, Temel Tıp Bilimleri Bölümü Koleksiyonu İçin Listeleme
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Comparison of DNA isolation methods from mammalian sperm cells and development of a new protocol
Nalkıran, Hatice Sevim; Nalkıran, İhsan; Rakıcı, Sema Yılmaz; Tümkaya, Levent; Güzel, Ali İrfan (Effect Publishing Agency ( EPA ), 2021)Sperm DNA tightly packed with protamines makes the DNA isolation procedure from sperm cells long and laborious. Cell lysis is also a challenging step because of the disulfide bonds-rich membranes of the sperm cells. In ... -
COVID-19 vaccine immunity in oncology patients
Uslu, Gonca Hanedan; Rakıcı, Sema Yılmaz; Çiçek, Ayşegül Çopur; Yazıcı, Zihni Açar (AEPRESS Sro, 2023)BACKGROUND: To investigate the effect of vaccine types applied in our country against 2019 coronavirus disease on the formation of protective antibodies in oncology patients. MATERIALS AND METHODS: The data of 81 cancer ... -
The effects of coenzyme Q10 (CoQ10) on Ionizing radiation- induced pancreatic β-cell injury
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz (AVES, 2023)Objective: This study investigated the antioxidant effect of coenzyme Q10 on ionizing radiation induced oxidative damage in pancreatic & beta;-cells. Methods: Twenty-four male rats were assigned to 4 groups. Group 1 ... -
Evaluation of the protective effect of coenzyme Q10 against x-ray irradiation-induced ovarian injury
Tekin, Yeşim Bayoğlu; Tümkaya, Levent; Mercantepe, Tolga; Topal, Zehra Suzan; Samancı, Tuğba Çelik; Yılmaz, Hülya Kılıç; Rakıcı, Sema Yılmaz; Topçu, Atilla (Wiley, 2024)Aim: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. Methods: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group ... -
Investigation of a glioblastoma risk-associated SNP of the PTPRB Gene in familial glioblastoma
Sevim Nalkıran, Hatice; Rakıcı, Sema Yılmaz; Nalkıran, İhsan (Turkiye Klinikleri, 2023)Objective: To investigate the association of the single nucleotide polymorphism (SNP) rs2252784 in the protein tyrosine phos-phatase receptor type B (PTPRB) gene with familial glioblastoma multiforme (GBM). Material and ... -
Pelvic radiation-induced testicular damage: an experimental study at 1 gray
Rakıcı, Sema Yılmaz; Güzel, Ali İrfan; Tümkaya, Levent; Nalkıran, Hatice Sevim; Mercantepe, Tolga (Taylor & Francis Inc, 2020)Therapeutic radiation of the pelvic region has been shown to cause damage to testicular germ cells. in this study we aimed to evaluate the effects of a low therapeutic dose of 1 Gy on the induction of cellular and histological ... -
The protective effects of red ginseng and amifostine against renal damage caused by ionizing radiation
Yılmaz, Hamit; Karakoç, Yunus; Tümkaya, Levent; Mercantepe, Tolga; Sevinç, Hacer; Yılmaz, Adnan; Rakıcı, Sema Yılmaz (2022)This study aimed to elucidate the effects of amifostine (ethyol) (AM), a synthetic radioprotector, and red ginseng (RG), a natural radioprotective agent, against the toxic effect of ionizing radiation (IR) on kidney tissues ... -
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats
Rakıcı, Sema Yılmaz; Tümkaya, Levent; Erdivanlı, Özlem Çelebi; Yazıcı, Ufuk; Dursun, Engin; Arpa, Medeni; Mercantepe, Tolga (Taylor & Francis Ltd, 2019)Purpose: We investigated the radioprotective effect of endogenous melatonin release at different times associated with the circadian rhythm on head and neck radiotherapy. Materials and methods: Two groups of animals were ... -
Radioprotective effects of alpha 2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Çiftel, Serpil; Çiftel, Sedat (Springer, 2023)Comprehensive epidemiological analyses conducted in the last 30 years have revealed a link between radiation and DM. We aimed to determine the effects of dexmedetomidine pretreatment on radiation-induced pancreatic islet ... -
Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage
Dil, Eyüp; Tümkaya, Levent; Mercantepe, Tolga; Rakıcı, Sema Yılmaz; Yılmaz, Adnan; Samancı, Tuğba Çelik; Yazıcı, Zihni Açar (Verduci Publisher, 2023)OBJECTIVE: Approximately 70% of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of cancer, radiotherapy can also affect and damage surrounding healthy tissues in addition to ... -
Wernicke's encephalopathy in a patient with unresectable gastric carcinoma and literature review
Rakıcı, Sema Yılmaz; Erdemli, Sema Doğan; Yazıcı, Zihni Açar; Cengiz, Ercüment; Acar, Özlem Günay; Tufan, Gülnihal (E-Century Publishing Corp, 2015)Wernicke's encephalopathy (WE) is a disease classically associated with nutrition deficiency. It is characterized by typical symptoms like confusion, ataxia and ophthalmoparesis, and developes due to thiamine deficieny in ...