Kurum Yazarı "Yüce, Süleyman" TF, Temel Tıp Bilimleri Bölümü Koleksiyonu İçin Listeleme
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Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats
Cüre, Erkan; Cüre, Medine Cumhur; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İbrahim; Kırbaş, Aynur; Yılmaz, Arif; Yüce, Süleyman; Yücel, Ahmet Fikret (Hindawi Ltd, 2014)The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ... -
Biochemical and histopathological effects on the rat testis after exposure to electromagnetic field during fetal period
Şehitoğlu, İbrahim; Tümkaya, Levent; Kalkan, Yıldıray; Bedir, Recep; Cüre, Medine Cumhur; Zorba, Orhan Ünal; Cüre, Erkan; Yüce, Süleyman (Iniestares, S.A., 2015)OBJECTIVES: Electromagnetic radiation (ER) emitted from cell phones may exert a detrimental influence on human health and may affect the man reproductive system. We aimed to study the biological and morphological effects ... -
Clinical potential of resistin as a novel prognostic biomarker for cellulitis
Ertürk, Ayşe; Cüre, Medine Cumhur; Cüre, Erkan; Kurt, Aysel; Çiçek, Ayşegül Çopur; Yüce, Süleyman (Spandidos Publ Ltd, 2015)Cellulitis is an acute, subacute or chronic inflammation of the dermis and subdermal tissues, which is typically caused by bacteria, although other causes are possible. the present study aimed to evaluate the association ... -
Clinical significance of neutrophil gelatinase-associated lipocalin in crimean-congo hemorrhagic fever
Ertürk, Ayşe; Cüre, Erkan; Parlak, Emine; Cüre, Medine Cumhur; Şahin, Serap Baydur; Yüce, Süleyman (Hindawi Ltd, 2015)Neutrophil gelatinase-associated lipocalin (NGAL), which is an important prognostic marker for sepsis and inflammatory diseases, is mostly released from neutrophils. Crimean-Congo hemorrhagic fever (CCHF) patients are ... -
The effect of Gilbert’s syndrome on the dispersions of QT interval and P-wave: an observational study
Amaç: Gilbert sendromu (GS) aterosklerotik kalphastalığı sıklığını azaltır. Bu çalışmanın amacı P dalga dispersiyonu (Pd), QT dispersiyonu (QTd) gibi aritmi risk belirteçlerinin sağlıklı bireylerle kıyaslandığında GS’li ... -
Effect of infliximab against cisplatin-induced nephrotoxicity
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Şahin, Osman Zikrullah; Kalkan, Yıldıray; Yüce, Süleyman; Altuner, Durdu (Saudi Med J, 2014)Objectives: To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-alpha), prevents cisplatin (Cis)-induced nephrotoxicity. Methods: the study was performed in the Department of Internal ... -
Effect of infliximab on renal injury due to methotrexate in rat
Kırbaş, Aynur; Cüre, Medine Cumhur; Kalkan, Yıldıray; Cüre, Erkan; Tümkaya, Levent; Şahin, Osman Zikrullah; Yüce, Süleyman; Kızılkaya, Bayram; Pergel, Ahmet (Iranian Soc Nephrolgy, 2015)Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ... -
The effects of Gilbert's syndrome on the mean platelet volume and other hematological parameters
Cüre, Medine Cumhur; Cüre, Erkan; Kırbaş, Aynur; Çiçek, Aysegül Çopur; Yüce, Süleyman (Lippincott Williams & Wilkins, 2013)The protective effect of increased levels of indirect bilirubin on atherosclerotic heart disease in patients of Gilbert's syndrome is well known. the aim of the study was to investigate the effects of increased levels of ... -
Evaluation of aortic stiffness in Gilbert syndrome patients: a protective effect of elevated bilirubin levels
Yüce, Süleyman; Cüre, Erkan; Çiçek, Yüksel; Cüre, Medine Cumhur; Yılmaz, Arif; Kızılkaya, Bayram (2015)Amaç: Gilbert sendromu (GS) indirekt bilirubin artışıyla karakterize otozomal resesif bir hastalıktır. Gilbert sendromunda aterosklerotik kalp hastalığı insidansı azalmıştır. Biz bu çalışmada GS’nin varlığı ve nabız dalga ... -
The evaluation of relationship between adiponectin levels and epicardial adipose tissue thickness with low cardiac risk in Gilbert's syndrome: an observational study
Cüre, Erkan; Çiçek, Yüksel; Cüre, Medine Cumhur; Yüce, Süleyman; Kırbaş, Aynur; Yılmaz, Arif (Turkish Soc Cardiology, 2013)Amaç: Gilbert sendromlu (GS) hastalarda aterosklerotik kalp hastalıkları daha az sıklıkla görülmektedir. Bilirubinin antioksidan etkisi yanında serum adiponektin (APN) ve epikardiyal yağ doku (EYD) kalınlığının aterosklerotik ... -
Has the required importance been given to the diagnosis and treatment of prediabetes?
Yüce, Süleyman; Cüre, Erkan; Sezgin, Hacer; Cüre, Medine Cumhur; Algün, Ekrem (Isfahan University of Medical Sciences(IUMS), 2014)DEAR EDITOR, The incidence of prediabetes increases steadily due to increasing obesity, consumption of fast food and sedentary lifestyle. Diet, increasing physical activities and metformin/acarbose therapy are used in ... -
Mean platelet volume and vitamin D level
Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Yazıcı, Tarkan; Karakoyun, İnanç; Efe, Hasan (Korean Soc Laboratory Medicine, 2014)Background: Vitamin D deficiency and a high mean platelet volume (MPV) are related to cardiovascular disease. We investigated whether vitamin D deficiency is associated with high MPV. Methods: This study included 434 ... -
Nesfatin-1 and Vitamin D levels may be associated with systolic and diastolic blood pressure values and hearth rate in polycystic ovary syndrome
Şahin, Figen Kır; Şahin, Serap Baydur; Ural, Ülkü Mete; Cüre, Medine Cumhur; Şentürk, Şenol; Tekin, Yeşim Bayoğlu; Balık, Gülşah; Cüre, Erkan; Yüce, Süleyman; Kırbaş, Aynur (Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2015)Obesity, insulin resistance (IR), inflammation, and hyperandrogenism may lead to polycystic ovary syndrome (PCOS) and hypertension. Nesfatin-1 (N1) may be related to IR, obesity, and hypertension. Furthermore, a vitamin D ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Tümkaya, Levent; Aydın, İbrahim; Kırbaş, Aynur; Efe, Hasan; Kurt, Aysel; Yüce, Süleyman (Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Kalkan, Yıldıray; Yılmaz, Arif; Yüce, Süleyman (Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
Serum resistin levels may be new prognostic factor of crimean-congo hemorrhagic fever
Ertürk, Ayşe; Cüre, Erkan; Parlak, Emine; Cüre, Medine Cumhur; Yüce, Süleyman; Kızılkaya, Bayram (E-Century Publishing Corp, 2014)Crimean-Congo hemorrhagic fever (CCHF) virus can cause potentially fatal infections in humans. During this disease, cytokines are intensive released. Resistin which is a good marker of inflammation is an adipocytokine ... -
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
Cüre, Erkan; Cüre, Medine Cumhur; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İbrahim; Kırbaş, Aynur; Yılmaz, Arif; Yüce, Süleyman; Gökçe, Mehmet Fatih (Wolters Kluwer Medknow Publications, 2014)Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ... -
Topiramate has protective effect on renal injury
Cüre, Medine Cumhur; Cüre, Erkan; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İlkyaz; Kırbaş, Aynur; Efe, Hasan; Şehitoğlu, İbrahim; Yüce, Süleyman (Comenius Univ, 2015)Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ...